Search Results - "Peñarroya, Alfonso"
-
1
Epigenetic Study of Cohort of Monozygotic Twins With Hypertrophic Cardiomyopathy Due to MYBPC3 (Cardiac Myosin-Binding Protein C)
Published in Journal of the American Heart Association (05-11-2024)“…Hypertrophic cardiomyopathy is an autosomal dominant cardiac disease. The mechanisms that determine its variable expressivity are poorly understood…”
Get full text
Journal Article -
2
HepGentox: a novel promising HepG2 reportergene-assay for the detection of genotoxic substances in complex mixtures
Published in PeerJ (San Francisco, CA) (27-07-2021)“…In risk assessment, genotoxicity is a key factor to determine the safety for the consumer. Most genotoxicity assays were developed for the assessment of pure…”
Get full text
Journal Article -
3
Enhanced Detection of Viral RNA Species Using FokI-Assisted Digestion of DNA Duplexes and DNA/RNA Hybrids
Published in Analytical chemistry (Washington) (10-05-2022)“…The accurate detection of nucleic acids from certain biological pathogens is critical for the diagnosis of human diseases. However, amplified detection of RNA…”
Get full text
Journal Article -
4
A multiomic atlas of the aging hippocampus reveals molecular changes in response to environmental enrichment
Published in Nature communications (16-07-2024)“…Aging involves the deterioration of organismal function, leading to the emergence of multiple pathologies. Environmental stimuli, including lifestyle, can…”
Get full text
Journal Article -
5
Physical exercise shapes the mouse brain epigenome
Published in Molecular metabolism (Germany) (01-12-2021)“…To analyze the genome-wide epigenomic and transcriptomic changes induced by long term resistance or endurance training in the hippocampus of wild-type mice. We…”
Get full text
Journal Article -
6
CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer
Published in Clinical epigenetics (24-08-2023)“…Background Promoter hypermethylation of tumour suppressor genes is frequently observed during the malignant transformation of colorectal cancer (CRC). However,…”
Get full text
Journal Article -
7
Classification of follicular-patterned thyroid lesions using a minimal set of epigenetic biomarkers
Published in European journal of endocrinology (01-09-2022)“…Objective The minimally invasive fine-needle aspiration cytology (FNAC) is the current gold standard for the diagnosis of thyroid nodule malignancy. However,…”
Get full text
Journal Article