Search Results - "Peluso, John J."

Cyclic Regulation of Sensory Perception by a Female Hormone Alters Behavior by Dey, Sandeepa, Chamero, Pablo, Pru, James K., Chien, Ming-Shan, Ibarra-Soria, Ximena, Spencer, Kathryn R., Logan, Darren W., Matsunami, Hiroaki, Peluso, John J., Stowers, Lisa

“…Females may display dramatically different behavior depending on their state of ovulation. This is thought to occur through sex-specific hormones acting on…”
Get full text

Multiplicity of Progesterone's Actions and Receptors in the Mammalian Ovary by PELUSO, John J

“…This minireview summarizes the role that progesterone (P4) plays in regulating granulosa and luteal cell function. These actions include the stimulation of P4…”
Get full text

Progesterone Signaling and Mammalian Ovarian Follicle Growth Mediated by Progesterone Receptor Membrane Component Family Members by Peluso, John J

“…How progesterone influences ovarian follicle growth is a difficult question to answer because ovarian cells synthesize progesterone and express not only the…”
Get full text

AG 205, a progesterone receptor membrane component 1 antagonist, ablates progesterone's ability to block oxidative stress-induced apoptosis of human granulosa/luteal cells by Will, Erica Anspach, Liu, Xiufang, Peluso, John J.

“…The present studies were designed to determine whether progesterone (P4)-progesterone receptor membrane component 1 (PGRMC1) signaling is able to attenuate the…”
Get full text

Progesterone receptor membrane component 1 and its role in ovarian follicle growth by Peluso, John J

“…Progesterone (P4) is synthesized in the ovary and acts directly on granulosa cells of developing ovarian follicles to suppress their rate of mitosis and…”
Get full text

Non-canonical progesterone signaling in granulosa cell function by Peluso, John J, Pru, James K

“…It has been known for over 3 decades that progesterone (P4) suppresses follicle growth. It has been assumed that P4 acts directly on granulosa cells of…”
Get full text

Progesterone Receptor Membrane Component-1 (PGRMC1) Is the Mediator of Progesterone’s Antiapoptotic Action in Spontaneously Immortalized Granulosa Cells As Revealed by PGRMC1 Small Interfering Ribonucleic Acid Treatment and Functional Analysis of PGRMC1 Mutations by Peluso, John J, Romak, Jonathan, Liu, Xiufang

“…Progesterone (P4) receptor membrane component-1 (PGRMC1) and its binding partner, plasminogen activator inhibitor 1 RNA binding protein (PAIRBP1) are thought…”
Get full text

Conditional Ablation of Progesterone Receptor Membrane Component 1 Results in Subfertility in the Female and Development of Endometrial Cysts by McCallum, Melissa L, Pru, Cindy A, Niikura, Yuichi, Yee, Siu-Pok, Lydon, John P, Peluso, John J, Pru, James K

“…Progesterone (P4) is essential for female fertility. The objective of this study was to evaluate the functional requirement of the nonclassical P4 receptor…”
Get full text

Progesterone Regulation of Progesterone Receptor Membrane Component 1 (PGRMC1) Sumoylation and Transcriptional Activity in Spontaneously Immortalized Granulosa Cells by Peluso, John J, Lodde, Valentina, Liu, Xiufang

“…Progesterone (P4) receptor membrane component (PGRMC)1 is detected as a 22-kDa band as well as higher molecular mass bands (>50 kDa) in spontaneously…”
Get full text

Supplementing culture medium with the weak acid, 5,5-dimethyl-2,4-oxazolidinedione (DMO) limits the development of aneuploid mouse embryos through a Trp53-dependent mechanism by Lowther, Katie M., Bartolucci, Alison F., Massey, Rachael E., Brown, Judy, Peluso, John J.

“…Purpose This study was designed to determine if DMO limits in vitro development of aneuploid-enriched mouse embryos by activating a Trp53 -dependent mechanism…”
Get full text

Progesterone receptor membrane component 1 deficiency attenuates growth while promoting chemosensitivity of human endometrial xenograft tumors by Friel, Anne M, Zhang, Ling, Pru, Cindy A, Clark, Nicole C, McCallum, Melissa L, Blok, Leen J, Shioda, Toshi, Peluso, John J, Rueda, Bo R, Pru, James K

“…Abstract Endometrial cancer is the leading gynecologic cancer in women in the United States with 52,630 women predicted to be diagnosed with the disease in…”
Get full text

Regulation of Ovarian Cancer Cell Viability and Sensitivity to Cisplatin by Progesterone Receptor Membrane Component-1 by Peluso, John J., Liu, Xiufang, Saunders, M. Melinda, Claffey, Kevin P., Phoenix, Kathryn

“…Context: Progesterone (P4) influences ovarian cancer cells by an unknown mechanism. Objective: The objective was to determine whether P4 acts through…”
Get full text

Progesterone Regulation of Human Granulosa/Luteal Cell Viability by an RU486-Independent Mechanism by Engmann, Lawrence, Losel, Ralf, Wehling, Martin, Peluso, John J.

“…Context: Progesterone (P4) inhibits human granulosa/luteal cell apoptosis by an unknown mechanism. Objective: Our objective was to assess the role of the…”
Get full text

PGRMC1/2 promote luteal vascularization and maintain the primordial follicles of mice by Peluso, John J, Liu, Xiufang, Uliasz, Tracy, Pru, Cindy A., Kelp, Nicole C., Pru, James

“…To determine whether conditional depletion of Progesterone Receptor Membrane Component (PGRMC) 1 and PGRMC2 affected ovarian follicle development, follicle…”
Get full text

The relationship between follicle development and progesterone receptor membrane component-1 expression in women undergoing in vitro fertilization by Elassar, Alyaa, M.D, Liu, Xiufang, Scranton, Victoria, Wu, Carol A., Ph.D, Peluso, John J., Ph.D

“…Objective To determine the relationship between progesterone receptor membrane component-1 (PGRMC1) expression and the outcome of IVF treatment. Design A…”
Get full text

Progesterone receptor membrane component 1 expression and putative function in bovine oocyte maturation, fertilization, and early embryonic development by Luciano, Alberto M, Lodde, Valentina, Franciosi, Federica, Ceciliani, Fabrizio, Peluso, John J

“…Although the mRNA that encodes progesterone receptor membrane component 1 (PGRMC1) is present in mammalian oocytes, nothing is known about either PGRMC1's…”
Get full text

Progesterone Receptor Membrane Component-1 Regulates the Development and Cisplatin Sensitivity of Human Ovarian Tumors in Athymic Nude Mice by Peluso, John J, Gawkowska, Anna, Liu, Xiufang, Shioda, Toshi, Pru, James K

“…To determine whether progesterone receptor membrane component 1 (PGRMC1) regulates the development and cisplatin (CDDP)-sensitivity of human ovarian tumors,…”
Get full text

Expression of progesterone receptor membrane component 1 and its partner serpine 1 mRNA binding protein in uterine and placental tissues of the mouse and human by Zhang, Ling, Kanda, Yoshiaki, Roberts, Drucilla J., Ecker, Jeffrey L., Losel, Ralf, Wehling, Martin, Peluso, John J., Pru, James K.

“…Although activation of the nuclear progesterone (P 4) receptor (PGR) is required for uterine function, some of the actions of P 4 are mediated through a…”
Get full text

Progestin and AdipoQ Receptor 7, Progesterone Membrane Receptor Component 1 (PGRMC1), and PGRMC2 and Their Role in Regulating Progesterone's Ability to Suppress Human Granulosa/Luteal Cells from Entering into the Cell Cycle by Sueldo, Carolina, Liu, Xiufang, Peluso, John J

“…The present studies were designed to determine the role of progesterone receptor membrane component 1 (PGRMC1), PGRMC2, progestin and adipoQ receptor 7…”
Get full text

Expression of Progesterone Receptor Membrane Component-2 Within the Immature Rat Ovary and Its Role in Regulating Mitosis and Apoptosis of Spontaneously Immortalized Granulosa Cells1 by Griffin, Daniel, Liu, Xiufang, Pru, Cindy, Pru, James K, Peluso, John J

“…Progesterone receptor membrane component 2 (Pgrmc2) mRNA was detected in the immature rat ovary. By 48 h after eCG, Pgrmc2 mRNA levels decreased by 40% and…”
Get full text