Search Results - "Pelosi Giuseppe"
-
1
Lack of imbalance between the master regulators TTF1/NKX2-1 and ΔNp63/p40 implies adverse prognosis in non-small cell lung cancer
Published in Scientific reports (30-01-2024)“…The transcription factors TTF1/NKX2-1 and ΔNp63/p40 are the counterposed molecular markers associated with the main Non-Small Cell Lung Cancer subtypes: TTF1…”
Get full text
Journal Article -
2
Clinical Response of Carcinomas Harboring the BRD4-NUT Oncoprotein to the Targeted Bromodomain Inhibitor OTX015/MK-8628
Published in Cancer discovery (01-05-2016)“…The antineoplastic, prodifferentiative effects of bromodomain and extra-terminal (BET) bromodomain (BRD) inhibitors were initially discovered in NUT midline…”
Get more information
Journal Article -
3
Morphologic and molecular classification of lung neuroendocrine neoplasms
Published in Virchows Archiv : an international journal of pathology (2021)“…Neuroendocrine neoplasms (NENs) of the lung encompass neuroendocrine tumors (NETs) composed of typical (TC) and atypical (AC) carcinoids and full-fledged…”
Get full text
Journal Article -
4
p40 (ΔNp63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma
Published in Modern pathology (01-03-2012)“…Immunohistochemistry has recently emerged as a powerful ancillary tool for differentiating lung adenocarcinoma and squamous cell carcinoma—a distinction with…”
Get full text
Journal Article -
5
TNM staging system of colorectal carcinoma: a critical appraisal of challenging issues
Published in Archives of pathology & laboratory medicine (1976) (01-06-2010)“…Colorectal cancer is the leading cause of morbidity and death among gastrointestinal tumors and ranks fourth after lung, breast, and ovarian cancers. Despite a…”
Get full text
Journal Article -
6
Comorbidities in idiopathic pulmonary fibrosis: an underestimated issue
Published in European respiratory review (30-09-2019)“…Idiopathic pulmonary fibrosis (IPF) is a progressive and fibrosing lung disease with a poor prognosis. Between 60% and 70% of IPF patients die of IPF; the…”
Get full text
Journal Article -
7
Alterations of the Notch pathway in lung cancer
Published in Proceedings of the National Academy of Sciences - PNAS (29-12-2009)“…Notch signaling regulates cell specification and homeostasis of stem cell compartments, and it is counteracted by the cell fate determinant Numb. Both Numb and…”
Get full text
Journal Article -
8
Acetyl-L-Carnitine downregulates invasion (CXCR4/CXCL12, MMP-9) and angiogenesis (VEGF, CXCL8) pathways in prostate cancer cells: rationale for prevention and interception strategies
Published in Journal of experimental & clinical cancer research (12-11-2019)“…Prostate cancer (PCa) is a leading cause of cancer-related death in males worldwide. Exacerbated inflammation and angiogenesis have been largely demonstrated…”
Get full text
Journal Article -
9
Establishment of patient derived xenografts as functional testing of lung cancer aggressiveness
Published in Scientific reports (27-07-2017)“…Despite many years of research efforts, lung cancer still remains the leading cause of cancer deaths worldwide. Objective of this study was to set up a…”
Get full text
Journal Article -
10
-
11
Overcoming Resistance to Checkpoint Inhibitors: Natural Killer Cells in Non-Small Cell Lung Cancer
Published in Frontiers in oncology (31-05-2022)“…Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatments over the last 10 years, with even increasing indications in many neoplasms. Non-small…”
Get full text
Journal Article -
12
Aggressive early-stage lung adenocarcinoma is characterized by epithelial cell plasticity with acquirement of stem-like traits and immune evasion phenotype
Published in Oncogene (05-08-2021)“…Lung adenocarcinoma (LUAD) is the main non-small-cell lung cancer diagnosed in ~40–50% of all lung cancer cases. Despite the improvements in early detection…”
Get full text
Journal Article -
13
Molecular Pathology of Well-Differentiated Pulmonary and Thymic Neuroendocrine Tumors: What Do Pathologists Need to Know?
Published in Endocrine pathology (01-03-2021)“…Thoracic (pulmonary and thymic) neuroendocrine tumors are well-differentiated epithelial neuroendocrine neoplasms that are classified into typical and atypical…”
Get full text
Journal Article -
14
A Subset of Large Cell Neuroendocrine Carcinomas in the Gastroenteropancreatic Tract May Evolve from Pre-existing Well-Differentiated Neuroendocrine Tumors
Published in Endocrine pathology (01-09-2021)“…In the gastro-entero-pancreatic (GEP) tract, neuroendocrine neoplasms (NENs) include well differentiated neuroendocrine tumors (NETs) and high-grade NE…”
Get full text
Journal Article -
15
Classification of pulmonary neuroendocrine tumors: new insights
Published in Translational lung cancer research (01-10-2017)“…Neuroendocrine tumors of the lung (Lu-NETs) embrace a heterogeneous family of neoplasms classified into four histological variants, namely typical carcinoid…”
Get full text
Journal Article -
16
Continuous Beam Steering For Phaseless Direction-of-Arrival Estimations
Published in IEEE antennas and wireless propagation letters (01-12-2019)“…This letter presents a system capable of continuous beam steering for direction-of-arrival (DoA) estimation operating at 2.45 GHz, based on the use of a…”
Get full text
Journal Article -
17
The differential diagnosis between pleural sarcomatoid mesothelioma and spindle cell/pleomorphic (sarcomatoid) carcinomas of the lung: evidence-based guidelines from the International Mesothelioma Panel and the MESOPATH National Reference Center
Published in Human pathology (01-09-2017)“…Immunohistochemistry is used to distinguish sarcomatoid malignant mesotheliomas (SMM) from spindle cell and pleomorphic carcinomas (SPC) but there are no…”
Get full text
Journal Article -
18
Transformation Optics Combined With Line-Integrals for Fast and Efficient Mode Matching Analysis of Waveguide Devices
Published in IEEE journal of microwaves (01-07-2023)“…Mode matching method is here applied to waveguide fields calculated in a transformation optics framework. The proposed approach allows to obtain modes in terms…”
Get full text
Journal Article -
19
Exact conic section arc elements in 2D and 2.5D FEM using a coordinate transformation
Published in IET microwaves, antennas & propagation (01-07-2021)“…This study introduces the conic section arc elements in 2D and 2.5D finite element method (FEM). Elements are obtained by deforming an edge in a standard…”
Get full text
Journal Article -
20
Mammalian target of rapamycin signaling activation patterns in neuroendocrine tumors of the lung
Published in Endocrine-related cancer (01-12-2010)“…Among alternative therapeutic strategies in clinically aggressive neuroendocrine tumors (NETs) of the lung, promising results have been obtained in…”
Get full text
Journal Article