Search Results - "Pelloux, V"

Mutational analysis of melanocortin-4 receptor, agouti-related protein, and α-melanocyte-stimulating hormone genes in severely obese children by Dubern, Béatrice, Clément, Karine, Pelloux, Véronique, Froguel, Philippe, Girardet, Jean-Philippe, Guy-Grand, Bernard, Tounian, Patrick

“…Objective: To search for mutations in melanocortin pathway elements, that is, the melanocortin-4 receptor (MC4R ), agouti-related protein (AGRP ), and…”
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A genetic variation in the 5 'flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity by OTABE, S, CLEMENT, K, DINA, C, PELLOUX, V, GUY-GRAND, B, FROGUEL, P, VASSEUR, F

“…In obese French Caucasian subjects we previously described a silent UCP3 Tyr99Tyr mutation, associated with body mass index. We hypothesised that an unknown…”
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PO37 Dysregulation of SMRT/GPS2 Corepressor Complex Is Associated with Adipose Tissue Inflammation in Human Obesity by Toubal, A, Allili, R, Pelloux, V, Barsh, G, Clément, K, Treuter, E, Venteclef, N

“…Introduction Obesity has become a global epidemic and is one the most significant public health challenges of the 21st century. In recent years, more and more…”
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A polymorphism in the 5' untranslated region of the human ob gene is associated with low leptin levels by HAGER, J, CLEMENT, K, NORTH, M, FROGUEL, P, FRANCKE, S, DINA, C, RAISON, J, LAHLOU, N, RICH, N, PELLOUX, V, BASDEVANT, A, GUY-GRAND, B

“…To search the human ob gene for mutations and evaluate their role in massive obesity. Direct mutation screening of the gene and case-control association study…”
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Microarray profiling of human white adipose tissue after exogenous leptin injection by Taleb, S., Van Haaften, R., Henegar, C., Hukshorn, C., Cancello, R., Pelloux, V., Hanczar, B., Viguerie, N., Langin, D., Evelo, C., Zucker, J., Clément, K., Saris, W. H. M.

“…Background  Leptin is a secreted adipocyte hormone that plays a key role in the regulation of body weight homeostasis. The leptin effect on human white adipose…”
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Adipose tissue gene expression in patients with a loss of function mutation in the leptin receptor by Clément, K, Vega, N, Laville, M, Pelloux, V, Guy-Grand, B, Basdevant, A, Vidal, H

“…BACKGROUND: In order to maintain body weight regulation, leptin directly or indirectly signals nutritional changes to key organs, but little is known about its…”
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A sib-pair analysis study of 15 candidate genes in French families with morbid obesity: indication for linkage with islet 1 locus on chromosome 5q by CLEMENT, K, DINA, C, BASDEVANT, A, CHASTANG, N, PELLOUX, V, LAHLOU, N, BERLAN, M, LANGIN, D, GUY-GRAND, B, FROGUEL, P

“…A sib-pair analysis study of 15 candidate genes in French families with morbid obesity: indication for linkage with islet 1 locus on chromosome 5q. K Clément ,…”
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Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity by Bravo-San Pedro, José M, Sica, Valentina, Martins, Isabelle, Pol, Jonathan, Loos, Friedemann, Maiuri, Maria Chiara, Durand, Sylvère, Bossut, Noélie, Aprahamian, Fanny, Anagnostopoulos, Gerasimos, Niso-Santano, Mireia, Aranda, Fernando, Ramírez-Pardo, Ignacio, Lallement, Justine, Denom, Jessica, Boedec, Erwan, Gorwood, Philip, Ramoz, Nicolas, Clément, Karine, Pelloux, Veronique, Rohia, Alili, Pattou, François, Raverdy, Violeta, Caiazzo, Robert, Denis, Raphaël G P, Boya, Patricia, Galluzzi, Lorenzo, Madeo, Frank, Migrenne-Li, Stéphanie, Cruciani-Guglielmacci, Céline, Tavernarakis, Nektarios, López-Otín, Carlos, Magnan, Christophe, Kroemer, Guido

“…Autophagy facilitates the adaptation to nutritional stress. Here, we show that short-term starvation of cultured cells or mice caused the autophagy-dependent…”
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SMRT-GPS2 corepressor pathway dysregulation coincides with obesity-linked adipocyte inflammation by Toubal, Amine, Clément, Karine, Fan, Rongrong, Ancel, Patricia, Pelloux, Veronique, Rouault, Christine, Veyrie, Nicolas, Hartemann, Agnes, Treuter, Eckardt, Venteclef, Nicolas

“…Low-grade chronic inflammation is a major characteristic of obesity and results from deregulated white adipose tissue function. Consequently, there is interest…”
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Cathepsin S inhibition lowers blood glucose levels in mice by Lafarge, Jean-Charles, Pini, Maria, Pelloux, Véronique, Orasanu, Gabriela, Hartmann, Guido, Venteclef, Nicolas, Sulpice, Thierry, Shi, Guo-Ping, Clément, Karine, Guerre-Millo, Michèle

“…Aims/hypothesis Cathepsin S (CatS) belongs to a family of proteases that have been implicated in several disease processes. We previously identified CatS as a…”
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Needle and surgical biopsy techniques differentially affect adipose tissue gene expression profiles by Mutch, David M, Tordjman, Joan, Pelloux, Véronique, Hanczar, Blaise, Henegar, Corneliu, Poitou, Christine, Veyrie, Nicolas, Zucker, Jean-Daniel, Clément, Karine

“…Adipose tissue gene expression analysis in humans now provides a tremendous means to discover the physiopathologic gene targets critical for our understanding…”
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A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction by Froguel, Philippe, Clément, Karine, Vaisse, Christian, Lahlou, Najiba, Cabrol, Sylvie, Pelloux, Veronique, Cassuto, Dominique, Gourmelen, Micheline, Dina, Christian, Chambaz, Jean, Lacorte, Jean-Marc, Basdevant, Arnaud, Bougnères, Pierre, Lebouc, Yves, Guy-Grand, Bernard

“…The adipocyte-specific hormone leptin, the product of the obese (ob) gene,regulates adipose-tissue mass through hypothalamic effects on satiety and energy…”
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Adipose gene expression prior to weight loss can differentiate and weakly predict dietary responders by Mutch, David M, Temanni, M Ramzi, Henegar, Corneliu, Combes, Florence, Pelloux, Véronique, Holst, Claus, Sørensen, Thorkild I A, Astrup, Arne, Martinez, J Alfredo, Saris, Wim H M, Viguerie, Nathalie, Langin, Dominique, Zucker, Jean-Daniel, Clément, Karine

“…The ability to identify obese individuals who will successfully lose weight in response to dietary intervention will revolutionize disease management…”
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Gene expression profiling of human skeletal muscle in response to stabilized weight loss by Larrouy, Dominique, Barbe, Pierre, Valle, Carine, Déjean, Sébastien, Pelloux, Véronique, Thalamas, Claire, Bastard, Jean-Philippe, Le Bouil, Anne, Diquet, Bertrand, Clément, Karine, Langin, Dominique, Viguerie, Nathalie

“…BACKGROUND:Diet-induced weight reduction promotes a decrease in resting energy expenditure that could partly explain the difficulty in maintaining reduced body…”
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Fréquence des mutations des gènes de la voie leptine/mélanocortines dans l’obésité sévère by Le Beyec-Le Bihan, J., Christine Poitou-Bernert, C., Karsenty, A., Pelloux, V., Lacorte, J.M., Tounian, P., Oppert, J.M., Clement, K., Dubern, B.

“…Clinique. La voie leptine/mélanocortines joue un rôle critique dans le contrôle hypothalamique de la prise alimentaire. Des mutations sur les gènes de cette…”
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Identification de gènes candidats par séquençage d’exome dans l’obésité syndromique by Huvenne, H., Trégouët, D.-A., Pelloux, V., Alili, R., Clément, K., Poitou, C., Dubern, B.

“…Les obésités syndromiques sont des modèles d’obésité sévère à début précoce, associée à une atteinte multiviscérale (retard mental, dysmorphie, atteintes…”
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Dysregulation of SMRT/GPS2 Corepressor Complex Is Associated with Adipose Tissue Inflammation in Human Obesity by Toubal, A, Allili, R, Pelloux, V, Barsh, G, Clement, K, Treuter, E, Venteclef, N

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SFP CO-69 - Inflammation systémique et tissulaire dans le syndrome de Prader-Willi by Lacroix, D., Moutel, S., Coupaye, M., Pelloux, V., Clément, K., Poitou, C., Dubern, B.

“…Le syndrome de Prader-Willi (SPW) représente un modèle de développement extrême et précoce du tissu adipeux (TA). Le but de ce travail était d’étudier les…”
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Subeutaneous adipose gene expression prior to weight loss can differentiate and weakly predict dietary responders by Martinez, J.A, Viguerie, N, Holst, C, Saris, W.H.M, Astrup, A, Langin, D, Temanni, M.R, Clement, K, Zucker, J.D, Pelloux, V, Sorensen, T.I.A, Henegar, C, Match, D.M, Combes, F

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Association between CST3 rs2424577 Polymorphism and Corpulence Related Phenotypes during Lifetime in Populations of European Ancestry by Hooton, Henri, Dubern, Beatrice, Henegar, Corneliu, Paternoster, Lavinia, Nohr, Ellen A., Alili, Rohia, Rousseau, Francis, Pelloux, Veronique, Galan, Pilar, Hercberg, Serge, Arner, Peter, Sørensen, Thorkild I.A., Clément, Karine

“…Objective: Cystatin C, a protein coded by CST3 gene, is implicated in adipose tissue biology. Our hypothesis is that common variants in CST3 gene could play a…”
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