Search Results - "Pellizas, Claudia G."
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Endogenous thyrocyte-produced nitric oxide inhibits iodide uptake and thyroid-specific gene expression in FRTL-5 thyroid cells
Published in Journal of endocrinology (01-03-2007)“…Nitric oxide (NO) is a free radical that mediates a wide array of cell functions. It is generated from l-arginine by NO-synthase (NOS). Expression of NOS…”
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Functional Toll-like Receptor 4 Overexpression in Papillary Thyroid Cancer by MAPK/ERK-Induced ETS1 Transcriptional Activity
Published in Molecular cancer research (01-05-2018)“…Emerging evidence suggests that unregulated Toll-like receptor (TLR) signaling promotes tumor survival signals, thus favoring tumor progression. Here, the…”
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3
Tumor-stroma interaction increases CD147 expression in neoplastic B lymphocytes in chronic lymphocytic leukemia
Published in Blood cells, molecules, & diseases (01-05-2020)“…Chronic lymphocytic leukemia (CLL) microenvironment plays a critical role in disease pathogenesis. Matrix metalloproteinases (MMPs) are involved in CLL-B cell…”
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Antitumor Responses Stimulated by Dendritic Cells Are Improved by Triiodothyronine Binding to the Thyroid Hormone Receptor β
Published in Cancer research (Chicago, Ill.) (01-04-2015)“…Bidirectional cross-talk between the neuroendocrine and immune systems orchestrates immune responses in both physiologic and pathologic settings. In this…”
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5
Dissecting thyroid hormone transport and metabolism in dendritic cells
Published in Journal of endocrinology (01-02-2017)“…We reported thyroid hormone (TH) receptor expression in murine dendritic cells (DCs) and 3,5,3′-triiodothyronine (T3)-dependent stimulation of DC maturation…”
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Nuclear Factor (NF)-κB-dependent Thyroid Hormone Receptor β1 Expression Controls Dendritic Cell Function via Akt Signaling
Published in The Journal of biological chemistry (26-03-2010)“…Despite considerable progress in our understanding of the interplay between immune and endocrine systems, the role of thyroid hormones and their receptors in…”
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Cooperative nongenomic and genomic actions on thyroid hormone mediated-modulation of T cell proliferation involve up-regulation of thyroid hormone receptor and inducible nitric oxide synthase expression
Published in Journal of cellular physiology (01-12-2011)“…Thyroid hormones (THs) exert a broad range of actions on development, growth, and cell differentiation by both genomic and nongenomic mechanisms. THs regulate…”
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Differential expression of Low density lipoprotein Receptor–related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions
Published in Pathology, research and practice (01-01-2017)“…Metalloproteinases (MMPs) are relevant modulators of inflammation, tumor microenvironment, cancer invasion and metastasis. They can be regulated by the Low…”
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Control of dendritic cell maturation and function by triiodothyronine
Published in The FASEB journal (01-04-2008)“…Accumulating evidence indicates a functional crosstalk between immune and endocrine mechanisms in the modulation of innate and adaptive immunity. However, the…”
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10
Dexamethasone counteracts the immunostimulatory effects of triiodothyronine (T3) on dendritic cells
Published in Steroids (2012)“…► Effect of dexamethasone (Dex) on triiodothyronine (T3) action in dendritic cells (DC). ► Dex inhibits the immunostimulatory capacity of T3-matured DC. ► Dex…”
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17β-Estradiol stimulates the translocation of endogenous estrogen receptor α at the plasma membrane of normal anterior pituitary cells
Published in Molecular and cellular endocrinology (15-05-2012)“…► We show that about 8% of anterior pituitary cells expressed ERα in the plasmalemma. ► Short exposition to E2 and ERα agonist, PPT, increases the membrane ERα…”
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12
Congenital hypothyroidism with goitre caused by new mutations in the thyroglobulin gene
Published in Clinical endocrinology (Oxford) (01-09-2007)“…Summary Context Thyroid dyshormonogenesis is associated with mutations in the thyroglobulin (TG) gene and characterized by normal organification of iodide and…”
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13
Growth hormone treatment in children with idiopathic short stature: correlation of growth response with peripheral thyroid hormone action
Published in Clinical endocrinology (Oxford) (01-03-2011)“…Objective Idiopathic short stature (ISS) describes short children with normal GH secretion. Although GH treatment increases their heights, growth response to…”
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14
Bacterial Lipopolysaccharide Stimulates the Thyrotropin-Dependent Thyroglobulin Gene Expression at the Transcriptional Level by Involving the Transcription Factors Thyroid Transcription Factor-1 and Paired Box Domain Transcription Factor 8
Published in Endocrinology (Philadelphia) (01-07-2006)“…The bacterial lipopolysaccharide (LPS) is a biological activator that induces expression of multiple genes in several cell types. LPS has been proposed as an…”
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15
Differential modulation of liver and pituitary triiodothyronine and 9-cis retinoid acid receptors by insulin-like growth factor I in rats
Published in Thyroid (New York, N.Y.) (01-12-2002)“…Triiodothyronine (T(3)) exerts most of its effects through nuclear thyroid hormone receptors (TRs) that bind mainly as heterodimers with retinoid-X receptors…”
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Anaplastic thyroid cancer cell-secreted TGFβ1 plays a key role in inducing macrophage polarization of human monocytes
Published in American journal of cancer research (2024)“…Anaplastic thyroid cancer (ATC) is a clinically aggressive form of undifferentiated thyroid cancer with limited treatment options. Tumor-associated macrophages…”
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Somatotroph response to periodical IGF-I administration to male rats
Published in Acta histochemica (2000)“…Insulin-like growth factor I (IGF-I) downregulates growth hormone (GH) expression in pituitary cell cultures. However, in vivo different results were found…”
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18
Extracellular vesicles induce fibroblasts metalloproteinases expression in thyroid tumour microenvironment
Published in Journal of extracellular vesicles (01-01-2018)“…Background: The tumour microenvironment (TME), conformed by cellular and non-cellular components, promotes tumourigenesis in many solid malignancies…”
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19
Response of triiodothyronine-dependent enzyme activities to insulin-like growth factor I and growth hormone in cultured rat hepatocytes
Published in European journal of endocrinology (01-02-1996)“…Pellizas CG, Coleoni AH, Cabanillas AM, Masini-Repiso AM, Costamagna ME. Response of triiodothyronine-dependent enzyme activities to insulin-like growth factor…”
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20
17 beta -Estradiol stimulates the translocation of endogenous estrogen receptor alpha at the plasma membrane of normal anterior pituitary cells
Published in Molecular and cellular endocrinology (15-05-2012)“…In the present work we aimed at identifying ER alpha in the plasma membrane of normal anterior pituitary cells and investigated if 17 beta -estradiol was able…”
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