Search Results - "Pelletier, Stephane"

Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease by Malireddi, R K Subbarao, Gurung, Prajwal, Kesavardhana, Sannula, Samir, Parimal, Burton, Amanda, Mummareddy, Harisankeerth, Vogel, Peter, Pelletier, Stephane, Burgula, Sandeepta, Kanneganti, Thirumala-Devi

“…RIPK1 kinase activity has been shown to be essential to driving pyroptosis, apoptosis, and necroptosis. However, here we show a kinase activity-independent…”
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BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation by Llambi, Fabien, Wang, Yue-Ming, Victor, Bernadette, Yang, Mao, Schneider, Desiree M., Gingras, Sébastien, Parsons, Melissa J., Zheng, Janet H., Brown, Scott A., Pelletier, Stéphane, Moldoveanu, Tudor, Chen, Taosheng, Green, Douglas R.

“…The mitochondrial pathway of apoptosis is initiated by mitochondrial outer membrane permeabilization (MOMP). The BCL-2 family effectors BAX and BAK are thought…”
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SCYL pseudokinases in neuronal function and survival by Pelletier, Stephane

“…The generation of mice lacking SCYL1 or SCYL2 and the identification of Scyl1 as the causative gene in the motor neuron disease mouse model muscle…”
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Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration by Perciavalle, Rhonda M., Stewart, Daniel P., Koss, Brian, Lynch, John, Milasta, Sandra, Bathina, Madhavi, Temirov, Jamshid, Cleland, Megan M., Pelletier, Stéphane, Schuetz, John D., Youle, Richard J., Green, Douglas R., Opferman, Joseph T.

“…MCL-1, an anti-apoptotic BCL-2 family member that is essential for the survival of multiple cell lineages, is also among the most highly amplified genes in…”
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Rapid and robust optogenetic control of gene expression in Drosophila by di Pietro, Florencia, Herszterg, Sophie, Huang, Anqi, Bosveld, Floris, Alexandre, Cyrille, Sancéré, Lucas, Pelletier, Stéphane, Joudat, Amina, Kapoor, Varun, Vincent, Jean-Paul, Bellaïche, Yohanns

“…Deciphering gene function requires the ability to control gene expression in space and time. Binary systems such as the Gal4/UAS provide a powerful means to…”
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DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome by Samir, Parimal, Kesavardhana, Sannula, Patmore, Deanna M., Gingras, Sebastien, Malireddi, R. K. Subbarao, Karki, Rajendra, Guy, Clifford S., Briard, Benoit, Place, David E., Bhattacharya, Anannya, Sharma, Bhesh Raj, Nourse, Amanda, King, Sharon V., Pitre, Aaron, Burton, Amanda R., Pelletier, Stephane, Gilbertson, Richard J., Kanneganti, Thirumala-Devi

“…The cellular stress response has a vital role in regulating homeostasis by modulating cell survival and death. Stress granules are cytoplasmic compartments…”
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Apical stress fibers enable a scaling between cell mechanical response and area in epithelial tissue by López-Gay, Jesús M., Nunley, Hayden, Spencer, Meryl, di Pietro, Florencia, Guirao, Boris, Bosveld, Floris, Markova, Olga, Gaugue, Isabelle, Pelletier, Stéphane, Lubensky, David K., Bellaïche, Yohanns

“…Fiber tension enables tissue scaling Tissue development, homeostasis, and repair require cells to sense mechanical forces. Although many molecular actors…”
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Y-complex nucleoporins independently contribute to nuclear pore assembly and gene regulation in neuronal progenitors by Orniacki, Clarisse, Verrico, Annalisa, Pelletier, Stéphane, Souquet, Benoit, Coulpier, Fanny, Jourdren, Laurent, Benetti, Serena, Doye, Valérie

“…Besides assembling nuclear pore complexes, the conduits of nuclear transport, many nucleoporins also contribute to chromatin organization and gene expression,…”
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SCYL1 does not regulate REST expression and turnover by Gingras, Sebastien, Kuliyev, Emin, Pelletier, Stéphane

“…A recent study identified SCYL1 as one of the components of the oncogenic STP axis, which promotes triple-negative breast cancer by regulating degradation of…”
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Differential roles of caspase-1 and caspase-11 in infection and inflammation by Man, Si Ming, Karki, Rajendra, Briard, Benoit, Burton, Amanda, Gingras, Sebastien, Pelletier, Stephane, Kanneganti, Thirumala-Devi

“…Caspase-1, also known as interleukin-1β (IL-1β)-converting enzyme (ICE), regulates antimicrobial host defense, tissue repair, tumorigenesis, metabolism and…”
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A Small-Volume, Low-Cost, and Versatile Continuous Culture Device by Matteau, Dominick, Baby, Vincent, Pelletier, Stéphane, Rodrigue, Sébastien

“…Continuous culture devices can be used for various purposes such as establishing reproducible growth conditions or maintaining cell populations under a…”
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CRISPR-Cas9-mediated insertion of a short artificial intron for the generation of conditional alleles in mice by Cassidy, Annelise, Pelletier, Stephane

“…In this protocol, we describe the generation of conditional alleles in mice using the DECAI (DEgradation based on Cre-regulated Artificial Intron) approach. We…”
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The interaction between RIPK1 and FADD controls perinatal lethality and inflammation by Rodriguez, Diego A., Tummers, Bart, Shaw, Jeremy J.P., Quarato, Giovanni, Weinlich, Ricardo, Cripps, James, Fitzgerald, Patrick, Janke, Laura J., Pelletier, Stephane, Crawford, Jeremy Chase, Green, Douglas R.

“…Perturbation of the apoptosis and necroptosis pathways critically influences embryogenesis. Receptor-associated protein kinase-1 (RIPK1) interacts with…”
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Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression by Malireddi, R K Subbarao, Bynigeri, Ratnakar R, Kancharana, Balabhaskararao, Sharma, Bhesh Raj, Burton, Amanda R, Pelletier, Stephane, Kanneganti, Thirumala-Devi

“…Interleukin 1α (IL-1α) and IL-1β are the founding members of the IL-1 cytokine family, and these innate immune inflammatory mediators are critically important…”
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Matters of life and death: How estrogen and estrogen receptor binding to the immunoglobulin heavy chain locus may influence outcomes of infection, allergy, and autoimmune disease by Jones, Bart G., Penkert, Rhiannon R., Surman, Sherri L., Sealy, Robert E., Pelletier, Stephane, Xu, Beisi, Neale, Geoff, Maul, Robert W., Gearhart, Patricia J., Hurwitz, J.L.

“…•Males and females suffer differently from pathogens, allergies and autoimmunity.•ERα binds regulatory elements in the immunoglobulin heavy chain…”
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Generation of Casp8 Mice Using CRISPR-Cas9 Technology by Pelletier, Stephane, Tummers, Bart, Green, Douglas R.

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Generation of Casp8FL122/123GG Mice Using CRISPR-Cas9 Technology by Pelletier, Stephane, Tummers, Bart, Green, Douglas R.

“…The purpose of this protocol is to describe the generation of missense mutations in mice using CRISPR-Cas9 technology. The current protocol focuses on the…”
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One-step generation of a conditional allele in mice using a short artificial intron by Cassidy, Annelise M., Thomas, Destinée B., Kuliyev, Emin, Chen, Hanying, Pelletier, Stephane

“…Despite tremendous advances in genome editing technologies, generation of conditional alleles in mice has remained challenging. Recent studies in cells have…”
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Preconditioning for Edge-Preserving Image Super Resolution by Pelletier, S., Cooperstock, J. R.

“…We propose a simple preconditioning method for accelerating the solution of edge-preserving image super-resolution (SR) problems in which a linear…”
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Real-time free viewpoint video from a range sensor and color cameras by Pelletier, Stéphane, Cooperstock, Jeremy R.

“…We propose a method for computing a depth map at interactive rates from a set of closely spaced calibrated video cameras and a Time-of-Flight (ToF) camera. The…”
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