Search Results - "Pelletier, Jean"

Efficacy and safety of topical NSAIDs in the management of osteoarthritis: Evidence from real-life setting trials and surveys by Rannou, François, MD, PhD, Pelletier, Jean-Pierre, MD, Martel-Pelletier, Johanne, PhD

“…Abstract Topical non-steroidal anti-inflammatory drugs (NSAIDs) are recommended in international and national guidelines as an early treatment option for the…”
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A Phase II Trial of Lutikizumab, an Anti–Interleukin‐1α/β Dual Variable Domain Immunoglobulin, in Knee Osteoarthritis Patients With Synovitis by Fleischmann, Roy M., Bliddal, Henning, Blanco, Francisco J., Schnitzer, Thomas J., Peterfy, Charles, Chen, Su, Wang, Li, Feng, Sheng, Conaghan, Philip G., Berenbaum, Francis, Pelletier, Jean‐Pierre, Martel‐Pelletier, Johanne, Vaeterlein, Ole, Kaeley, Gurjit S., Liu, Wei, Kosloski, Matthew P., Levy, Gwen, Zhang, Lanju, Medema, Jeroen K., Levesque, Marc C.

“…Objective To assess the efficacy and safety of the anti–interleukin‐1α/β (anti–IL‐1α/β) dual variable domain immunoglobulin lutikizumab (ABT‐981) in patients…”
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Machine-learning-based patient-specific prediction models for knee osteoarthritis by Jamshidi, Afshin, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne

“…Osteoarthritis (OA) is an extremely common musculoskeletal disease. However, current guidelines are not well suited for diagnosing patients in the early stages…”
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Is perfectionism a killer of creative thinking? A test of the model of excellencism and perfectionism by Goulet‐Pelletier, Jean‐Christophe, Gaudreau, Patrick, Cousineau, Denis

“…The standards that a person pursue in life can be set in a rigid or flexible way. The recent literature has emphasized a distinction between high and realistic…”
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Machine Learning–Based Individualized Survival Prediction Model for Total Knee Replacement in Osteoarthritis: Data From the Osteoarthritis Initiative by Jamshidi, Afshin, Pelletier, Jean‐Pierre, Labbe, Aurelie, Abram, François, Martel‐Pelletier, Johanne, Droit, Arnaud

“…Objective By using machine learning, our study aimed to build a model to predict risk and time to total knee replacement (TKR) of an osteoarthritic knee…”
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Role of proinflammatory cytokines in the pathophysiology of osteoarthritis by Martel-Pelletier, Johanne, Kapoor, Mohit, Lajeunesse, Daniel, Pelletier, Jean-Pierre, Fahmi, Hassan

“…The etiology and pathogenesis of osteoarthritis (OA) are poorly understood, although proinflammatory cytokines are known to be critically implicated in the…”
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Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis by Zhang, Yue, Vasheghani, Faezeh, Li, Ying-Hua, Blati, Meryem, Simeone, Kayla, Fahmi, Hassan, Lussier, Bertrand, Roughley, Peter, Lagares, David, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Kapoor, Mohit

“…Mammalian target of rapamycin (mTOR) (a serine/threonine protein kinase) is a major repressor of autophagy, a cell survival mechanism. The specific in vivo…”
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Virtual reality therapy for refractory auditory verbal hallucinations in schizophrenia: A pilot clinical trial by Percie du Sert, Olivier, Potvin, Stéphane, Lipp, Olivier, Dellazizzo, Laura, Laurelli, Mélanie, Breton, Richard, Lalonde, Pierre, Phraxayavong, Kingsada, O'Connor, Kieron, Pelletier, Jean-François, Boukhalfi, Tarik, Renaud, Patrice, Dumais, Alexandre

“…Schizophrenia is a chronic and severe mental illness that poses significant challenges. While many pharmacological and psychosocial interventions are…”
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An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: A report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) by Bruyère, Olivier, PhD, Cooper, Cyrus, MD, PhD, Pelletier, Jean-Pierre, MD, PhD, Branco, Jaime, MD, Luisa Brandi, Maria, MD, Guillemin, Francis, MD, PhD, Hochberg, Marc C., MD, PhD, Kanis, John A., MD, Kvien, Tore K., MD, PhD, Martel-Pelletier, Johanne, PhD, Rizzoli, René, MD, PhD, Silverman, Stuart, MD, Reginster, Jean-Yves, MD, PhD

“…Abstract Objectives Existing practice guidelines for osteoarthritis (OA) analyze the evidence behind each proposed treatment but do not prioritize the…”
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Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice by Leduc-Gaudet, Jean-Philippe, Picard, Martin, St-Jean Pelletier, Félix, Sgarioto, Nicolas, Auger, Marie-Joëlle, Vallée, Joanne, Robitaille, Richard, St-Pierre, David H, Gouspillou, Gilles

“…Skeletal muscle aging is associated with a progressive decline in muscle mass and strength, a process termed sarcopenia. Evidence suggests that accumulation of…”
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Efficacy and safety of oral NSAIDs and analgesics in the management of osteoarthritis: Evidence from real-life setting trials and surveys by Pelletier, Jean-Pierre, MD, Martel-Pelletier, Johanne, PhD, Rannou, François, MD, PhD, Cooper, Cyrus, MD, PhD

“…Abstract Non-steroidal anti-inflammatory drugs (NSAIDs) are at the cornerstone of treatment for osteoarthritis (OA). In recent years, the widespread use of…”
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Using ex vivo culture to assess dynamic phenotype changes in human prostate macrophages following exposure to therapeutic drugs by Boibessot, Clovis, Joncas, France-Hélène, Park, Aerin, Berrehail, Zohra, Pelletier, Jean-François, Gris, Typhaine, Bergeron, Alain, Toren, Paul

“…Within the prostate tumor microenvironment (TME) there are complex multi-faceted and dynamic communication occurring between cancer cells and immune cells…”
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Relaxation of Bulk Metallic Glasses Studied by Mechanical Spectroscopy by Qiao, Jichao, Pelletier, Jean-Marc, Casalini, Riccardo

“…The relaxational dynamics in metallic glasses (MGs) is investigated by using mechanical spectroscopy. The spectra show that in MGs there are two relaxations:…”
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Exploring Creative Spaces Predict Domain‐Specific Creative Achievements by Goulet‐Pelletier, Jean‐Christophe, Cousineau, Denis

“…ABSTRACT This study aimed to understand the factors predicting creative activities and creative achievements among university students. Based on a recently…”
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Role of Lipocalin‐Type Prostaglandin D Synthase in Experimental Osteoarthritis by Najar, Mehdi, Ouhaddi, Yassine, Paré, Frédéric, Lussier, Bertrand, Urade, Yoshihiro, Kapoor, Mohit, Pelletier, Jean‐Pierre, Martel‐Pelletier, Johanne, Benderdour, Mohamed, Fahmi, Hassan

“…Objective Lipocalin‐type prostaglandin D synthase (L‐PGDS) catalyzes the formation of prostaglandin D2 (PGD2), which has important roles in inflammation and…”
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An updated algorithm recommendation for the management of knee osteoarthritis from the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) by Bruyère, Olivier, Honvo, Germain, Veronese, Nicola, Arden, Nigel K., Branco, Jaime, Curtis, Elizabeth M., Al-Daghri, Nasser M., Herrero-Beaumont, Gabriel, Martel-Pelletier, Johanne, Pelletier, Jean-Pierre, Rannou, François, Rizzoli, René, Roth, Roland, Uebelhart, Daniel, Cooper, Cyrus, Reginster, Jean-Yves

“…The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) sought to revisit the 2014…”
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Effect of Intravenous Zoledronic Acid on Tibiofemoral Cartilage Volume Among Patients With Knee Osteoarthritis With Bone Marrow Lesions: A Randomized Clinical Trial by Cai, Guoqi, Aitken, Dawn, Laslett, Laura L, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Hill, Catherine, March, Lyn, Wluka, Anita E, Wang, Yuanyuan, Antony, Benny, Blizzard, Leigh, Winzenberg, Tania, Cicuttini, Flavia, Jones, Graeme

“…A proof-of-principle study suggested that intravenous zoledronic acid may reduce knee pain and the size of bone marrow lesions in people with knee…”
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Explainable artificial intelligence models for predicting risk of suicide using health administrative data in Quebec by Gholi Zadeh Kharrat, Fatemeh, Gagne, Christian, Lesage, Alain, Gariépy, Geneviève, Pelletier, Jean-François, Brousseau-Paradis, Camille, Rochette, Louis, Pelletier, Eric, Lévesque, Pascale, Mohammed, Mada, Wang, JianLi

“…Suicide is a complex, multidimensional event, and a significant challenge for prevention globally. Artificial intelligence (AI) and machine learning (ML) have…”
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Comparison of the Response to Rituximab between Myelin Oligodendrocyte Glycoprotein and Aquaporin‐4 Antibody Diseases by Durozard, Pierre, Rico, Audrey, Boutiere, Clémence, Maarouf, Adil, Lacroix, Romaric, Cointe, Sylvie, Fritz, Shirley, Brunet, Corinne, Pelletier, Jean, Marignier, Romain, Audoin, Bertrand

“…Objective To compare response to rituximab (RTX) between adult patients positive for myelin oligodendrocyte glycoprotein (MOG) and aquaporin‐4 (AQP4)…”
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Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes by Tardif, Ginette, Hum, David, Pelletier, Jean-Pierre, Duval, Nicolas, Martel-Pelletier, Johanne

“…MMP-13 and IGFBP-5 are important factors involved in osteoarthritis (OA). We investigated whether two highly predicted microRNAs (miRNAs), miR-140 and miR-27a,…”
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