Search Results - "Pelletier, J J"
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OARSI Clinical Trials Recommendations: Design and conduct of clinical trials for hand osteoarthritis
Published in Osteoarthritis and cartilage (01-05-2015)“…Summary Hand osteoarthritis (OA) is a very frequent disease, but yet understudied. However, a lot of works have been published in the past 10 years, and much…”
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Value of biomarkers in osteoarthritis: current status and perspectives
Published in Annals of the rheumatic diseases (01-11-2013)“…Osteoarthritis affects the whole joint structure with progressive changes in cartilage, menisci, ligaments and subchondral bone, and synovial inflammation…”
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Meniscal extrusion and bone marrow lesions are associated with incident and progressive knee osteoarthritis
Published in Osteoarthritis and cartilage (01-07-2017)“…Abstract Objective Whether meniscal extrusion and bone marrow lesions (BMLs) are independently associated with the risk of knee osteoarthritis (OA) is unknown…”
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Deletion of 12/15-lipoxygenase accelerates the development of aging-associated and instability-induced osteoarthritis
Published in Osteoarthritis and cartilage (01-10-2017)“…12/15-Lipoxygenase (12/15-LOX) catalyzes the generation of various anti-inflammatory lipid mediators, and has been implicated in several inflammatory and…”
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OARSI Clinical Trials Recommendations: Knee imaging in clinical trials in osteoarthritis
Published in Osteoarthritis and cartilage (01-05-2015)“…Summary Significant advances have occurred in our understanding of the pathogenesis of knee osteoarthritis (OA) and some recent trials have demonstrated the…”
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Gait risk factors for disease progression differ between non-traumatic and post-traumatic knee osteoarthritis
Published in Osteoarthritis and cartilage (01-11-2021)“…To examine if relationships between knee osteoarthritis (OA) progression with knee moments and muscle activation during gait vary between patients with…”
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Diagnostic validity and triage concordance of a physiotherapist compared to physicians' diagnoses for common knee disorders
Published in BMC musculoskeletal disorders (14-11-2017)“…Emergence of more autonomous roles for physiotherapists warrants more evidence regarding their diagnostic capabilities. Therefore, we aimed to evaluate…”
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Structural heterogeneities and mechanical behavior of amorphous alloys
Published in Progress in materials science (01-07-2019)“…Although the atomic structure of amorphous alloys, which lacks long-range translational symmetry, may appear homogeneous at the macroscopic scale, their local…”
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Journal Article Publication -
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Characterization of osteoarthritis in cats and meloxicam efficacy using objective chronic pain evaluation tools
Published in The veterinary journal (1997) (01-06-2013)“…This study aimed to characterize osteoarthritis (OA)-related chronic pain and disability in experimental cats with naturally occurring OA. Peak vertical ground…”
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OARSI Clinical Trials Recommendations: Hip imaging in clinical trials in osteoarthritis
Published in Osteoarthritis and cartilage (01-05-2015)“…Summary Imaging of hip in osteoarthritis (OA) has seen considerable progress in the past decade, with the introduction of new techniques that may be more…”
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The ratio adipsin/MCP-1 is strongly associated with structural changes and CRP/MCP-1 with symptoms in obese knee osteoarthritis subjects: data from the Osteoarthritis Initiative
Published in Osteoarthritis and cartilage (01-08-2019)“…There is a need to identify reliable biomarkers that can predict knee osteoarthritis (OA) progression. We investigated a panel of adipokines and some related…”
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Intrinsic Correlation between the Fraction of Liquidlike Zones and the β Relaxation in High-Entropy Metallic Glasses
Published in Physical review letters (21-10-2022)“…Lacking the structural information of crystalline solids, the origin of the relaxation dynamics of metallic glasses is unclear. Here, we report the evolution…”
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Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs
Published in Annals of the rheumatic diseases (01-06-2003)“…Dual 5-LOX/COX inhibitors are potential new drugs to treat inflammation. They act by blocking the formation of both prostaglandins and leucotrienes but do not…”
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Journal Article Book Review -
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Effects of chondroitin sulfate in the pathophysiology of the osteoarthritic joint: a narrative review
Published in Osteoarthritis and cartilage (01-06-2010)“…Summary Objective Osteoarthritis is a chronic disease characterized by irreversible damage to joint structures, including loss of articular cartilage,…”
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Relationship between alignment and cartilage thickness in patients with non-traumatic and post-traumatic knee osteoarthritis
Published in Osteoarthritis and cartilage (01-04-2019)“…To compare cartilage thickness between patients with non-traumatic and post-traumatic knee osteoarthritis (OA) and healthy controls and to determine if disease…”
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Cellular and molecular mechanisms of action of transcranial direct current stimulation: evidence from in vitro and in vivo models
Published in The international journal of neuropsychopharmacology (01-01-2015)“…Transcranial direct current stimulation is a noninvasive technique that has been experimentally tested for a number of psychiatric and neurological conditions…”
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The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the dog
Published in Osteoarthritis and cartilage (01-10-2010)“…Summary The dog is a common model for study of osteoarthritis (OA). Subjective histologic scoring systems have often served as the reference standard for…”
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Journal Article Conference Proceeding -
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Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI
Published in Annals of the rheumatic diseases (01-06-2009)“…In a multicentre study to explore the effects of licofelone as a disease-modifying osteoarthritis drug in comparison with naproxen in patients with knee…”
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Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Published in Annals of the rheumatic diseases (01-01-2016)“…To compare the efficacy and safety of chondroitin sulfate plus glucosamine hydrochloride (CS+GH) versus celecoxib in patients with knee osteoarthritis and…”
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Histone deacetylase inhibitors suppress interleukin-1β-induced nitric oxide and prostaglandin E2 production in human chondrocytes
Published in Osteoarthritis and cartilage (01-10-2008)“…Summary Objective Overproduction of nitric oxide (NO) and prostaglandin E2 (PGE2 ) plays an important role in the pathogenesis of osteoarthritis (OA). In the…”
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