Search Results - "Pellegrino, Carla M."
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Novel Selective Neuropeptide Y2 Receptor PEGylated Peptide Agonists Reduce Food Intake and Body Weight in Mice
Published in Journal of medicinal chemistry (03-05-2007)“…Selective activation of the NPY2 receptor to suppress appetite provides an approach to obesity management. Selective NPY2 PEGylated peptide agonists are…”
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Journal Article -
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Contribution of site-specific PEGylation to the dipeptidyl peptidase IV stability of glucose-dependent insulinotropic polypeptide
Published in Bioorganic & medicinal chemistry letters (15-09-2005)“…Potent and DPPIV-stable PEGylated GIP peptides are reported. The effects of PEGylation of glucose-dependent insulinotropic polypeptide (GIP) on potency and…”
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Journal Article -
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Engineering of a VPAC2 Receptor Peptide Agonist To Impart Dipeptidyl Peptidase IV Stability and Enhance in Vivo Glucose Disposal
Published in Journal of medicinal chemistry (14-12-2006)“…VPAC2P-PEG is a VPAC2 receptor agonist peptide that acts as a glucose-dependent insulin secretagogue. Proteolysis by DPPIV may contribute to the in vivo…”
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Journal Article