Search Results - "Pellacani, Annalisa"

2-Aminopyridine Analogs Inhibit Both Enzymes of the Glyoxylate Shunt in Pseudomonas aeruginosa by McVey, Alyssa C, Bartlett, Sean, Kajbaf, Mahmud, Pellacani, Annalisa, Gatta, Viviana, Tammela, Päivi, Spring, David R, Welch, Martin

“…is an opportunistic pathogen responsible for many hospital-acquired infections. can thrive in diverse infection scenarios by rewiring its central metabolism…”
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Discovery process and pharmacological characterization of a novel dual orexin 1 and orexin 2 receptor antagonist useful for treatment of sleep disorders by Di Fabio, Romano, Pellacani, Annalisa, Faedo, Stefania, Roth, Adelheid, Piccoli, Laura, Gerrard, Philip, Porter, Rod A., Johnson, Christopher N., Thewlis, Kevin, Donati, Daniele, Stasi, Luigi, Spada, Simone, Stemp, Geoffrey, Nash, David, Branch, Clive, Kindon, Leanda, Massagrande, Mario, Poffe, Alessandro, Braggio, Simone, Chiarparin, Elisabetta, Marchioro, Carla, Ratti, Emiliangelo, Corsi, Mauro

“…The hypothalamic peptides orexin-A and orexin-B are potent agonists of two G-protein coupled receptors, namely the OX1 and the OX2 receptor. These receptors…”
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1,2,4-Triazolyl 5‑Azaspiro[2.4]heptanes: Lead Identification and Early Lead Optimization of a New Series of Potent and Selective Dopamine D3 Receptor Antagonists by Micheli, Fabrizio, Bacchi, Alessia, Braggio, Simone, Castelletti, Laura, Cavallini, Palmina, Cavanni, Paolo, Cremonesi, Susanna, Dal Cin, Michele, Feriani, Aldo, Gehanne, Sylvie, Kajbaf, Mahmud, Marchió, Luciano, Nola, Selena, Oliosi, Beatrice, Pellacani, Annalisa, Perdonà, Elisabetta, Sava, Anna, Semeraro, Teresa, Tarsi, Luca, Tomelleri, Silvia, Wong, Andrea, Visentini, Filippo, Zonzini, Laura, Heidbreder, Christian

“…A novel series of 1,2,4-triazolyl 5-azaspiro[2.4]­heptanes with high affinity and selectivity at the dopamine (DA) D3 receptor (D3R) is described. Some of…”
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2-Methyl-3-furanyl-4H-1,2,4-triazol-3-ylthioamides: A new class of selective orexin 2 antagonists by Micheli, Fabrizio, Antolini, Marinella, Di Fabio, Romano, Pellacani, Annalisa, Pozzan, Alfonso

“…A new class of selective orexin 2 antagonist was identified among commercial products. Initial SAR obtained using commercial derivatives only is presented. A…”
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The antidepressant fluoxetine blocks the human small conductance calcium-activated potassium channels SK1, SK2 and SK3 by Terstappen, Georg C., Pellacani, Annalisa, Aldegheri, Laura, Graziani, Francesca, Carignani, Corrado, Pula, Giordano, Virginio, Caterina

“…The effects of fluoxetine (Prozac™) on the activity of human small-conductance calcium-activated potassium (SK) channels were investigated utilizing a…”
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In vitro study of the combination gemcitabine + fludarabine on freshly isolated chronic lymphocytic leukemia cells by Tosi, P, Pellacani, A, Zinzani, PL, Magagnoli, M, Visani, G, Tura, S

“…Istituto di Ematologia ed Oncologia Medica "L. e A. Seragnoli", Policlinico S. Orsola, via Massarenti, 9, 40138 Bologna, Italy ptosi@med.unibo.it BACKGROUND…”
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Inv(16) acute myeloid leukemia cells show an increased sensitivity to cytosine arabinoside in vitro by Tosi, Patrizia, Visani, Giuseppe, Ottaviani, Emanuela, Testoni, Nicoletta, Pellacani, Annalisa, Tura, Sante

“…: Karyotype represents the major independent prognostic factor for response and remission duration in acute leukemia. In particular, it has been reported that…”
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Reduction of heat‐shock protein‐70 after prolonged treatment with retinoids: Biological and clinical implications by Tosi, Patrizia, Visani, Giuseppe, Ottaviani, Emanuela, Gibellini, Davide, Pellacani, Annalisa, Tura, Sante

“…Heat shock proteins (HSPs) are a group of highly conserved polypeptides involved in cellular response to heat or other physical or chemical stresses. It has…”
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In vitro treatment with retinoids decreases bcl-2 protein expression and enhances dexamethasone-induced cytotoxicity and apoptosis in multiple myeloma cells by Tosi, Patrizia, Pellacani, Annalisa, Visani, Giuseppe, Ottaviani, Emanuela, Ronconi, Sonia, Zamagni, Elena, Benni, Monica, Cavo, Michele, Tura, Sante

“…:  All‐trans retinoic acid (ATRA) has been shown to inhibit in vitro growth of multiple myeloma (MM) cells, and this effect can be further potentiated by the…”
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All-trans retinoic acid at low concentration directly stimulates normal adult megakaryocytopoiesis in the presence of thrombopoietin or combined cytokines by Visani, Giuseppe, Ottaviani, Emanuela, Zauli, Giorgio, Tosi, Patrizia, Pellacani, Annalisa, Isidori, Alessandro, Pierpaoli, Sabina, Tura, Sante

“…:  In order to investigate the direct effects of retinoids on normal adult hematopoietic progenitors, purified CD34+ cells were seeded in serum‐free cultures…”
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Cytotoxic Combination of Loxoribine with Fludarabine and Mafosfamide on Freshly Isolated B-Chronic Lymphocytic Leukemia Cells by Pellacani, Annalisa, Tosi, Patrizia, Luigizinzani, Pier, Ottaviani, Emanuela, Albertini, Patrizia, Magagnoli, Massimo, Tura, Sante

“…Fludarabine has shown a definite clinical activity in B-cell chronic lymphocytic leukemia (B-CLL). Recently it has been demonstrated that loxoribine, a guanine…”
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Adenoviral mediated gene transfer can be accomplished in human myeloid cell lines and is inhibited by all-trans retinoic acid-induced differentiation by Tosi, P, Pellacani, A, Visani, G, Ottaviani, E, Tura, S

“…Institute of Hematology and Medical Oncology Seragnon, University of Bologna, Italy. BACKGROUND AND OBJECTIVE: Gene transfection could potentially represent a…”
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Loxoribine Affects Fludarabine Activity on Freshly Isolated B-chronic Lymphocytic Leukemia Cells by Tosi, Patrizia, Zinzani, Pier Luigi, Pellacani, Annalisa, Ottaviani, Emanuela, Magagnoli, Massimo, Tura, Sante

“…Purine analogues like fludarabine have been shown to be superior to conventional therapy for B-cell chronic lymphocytic leukemia (B-CLL). In order to improve…”
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Retinoids increase idarubicin cytotoxicity in human myeloid leukemia cell lines by Tosi, P, Visani, G, Ottaviani, E, Pellacani, A, Manfroi, S, Tura, S

“…All-trans-retinoic acid (ATRA) has proven useful in acute promyelocytic leukemia (APL). In order to reduce the side effects and to improve the efficacy of this…”
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