Search Results - "Pelia, Ranjit"

Single-cell transcriptomics of rectal organoids from individuals with perianal fistulizing Crohn’s disease reveals patient-specific signatures by Murthy, Shanta, Anbazhagan, Murugadas, Maddipatla, Sushma Chowdary, Kolachala, Vasantha L., Dodd, Anne, Pelia, Ranjit, Cutler, David J., Matthews, Jason D., Kugathasan, Subra

“…Perianal fistulizing Crohn’s disease (CD) is a severe gastrointestinal disorder causing extensive mucosal damage with limited treatment options. Severe…”
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Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization by Geem, Duke, Hercules, David, Pelia, Ranjit S, Venkateswaran, Suresh, Griffiths, Anne, Noe, Joshua D, Dotson, Jennifer L, Snapper, Scott, Rabizadeh, Shervin, Rosh, Joel R, Baldassano, Robert N, Markowitz, James F, Walters, Thomas D, Ananthakrishnan, Ashwin, Sharma, Garima, Denson, Lee A, Hyams, Jeffrey S, Kugathasan, Subra

“…The evolution of complicated pediatric Crohn's disease (CD) in the era of anti-tumor necrosis factor (aTNF) therapy continues to be described. Because CD…”
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Profiling non-coding RNA levels with clinical classifiers in pediatric Crohn's disease by Pelia, Ranjit, Venkateswaran, Suresh, Matthews, Jason D, Haberman, Yael, Cutler, David J, Hyams, Jeffrey S, Denson, Lee A, Kugathasan, Subra

“…Crohn's disease (CD) is a heritable chronic inflammatory disorder. Non-coding RNAs (ncRNAs) play an important role in epigenetic regulation by affecting gene…”
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Persistent Inflammation of the Rectum in Perianal Fistulizing Crohn's Disease Is Associated With Goblet Cell Function by Washburn, Savannah, Maddipatla, Sushma C, Murthy, Shanta, Dodd, Anne, Pelia, Ranjit S, Kolachala, Vasantha L, Geem, Duke, Matthews, Jason D, Gibson, Greg, Kugathasan, Subra

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866 PRO-INFLAMMATORY SIRPα-EXPRESSING MONOCYTES AND MACROPHAGES MEDIATE ANTI-TNF REFRACTORY CROHN'S DISEASE IN CHILDREN by Geem, Duke, Maddipatia, Sushma C., Pelia, Ranjit S., Matthews, Jason, Anbazhagan, Murugadas, Kolachala, Vasantha, Dodd, Ann, Kugathasan, Subra

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PRO-INFLAMMATORY SIRPα-EXPRESSING MONOCYTES AND MACROPHAGES MEDIATE ANTI-TNF REFRACTORY CROHN'S DISEASE IN CHILDREN by Geem, Duke, Maddipatla, Sushma, Pelia, Ranjit, Venkateswaran, Suresh, Matthews, Jason, Anbazhagan, Murugadas, Kolachala, Vasantha, Dodd, Anne, Kugathasan, Subra

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12: MUCOSAL BIOPSY DERIVED MESENCHYMAL STROMAL CELLS DISPLAY FITNESS AND FUNCTIONALITY TO USE AS AUTOLOGOUS CELLULAR PHARMACEUTICALS FOR INFLAMMATORY BOWEL DISEASE by Anbazhagan, Murugadas, Geem, Duke, Venkateswaran, Suresh, Pelia, Ranjit S., Kolachala, Vasantha, Dodd, Ann, Matthews, Jason, Chinnadurai, Raghavan, Kugathasan, Subra

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PRO-INFLAMMATORY SIRPα-EXPRESSING MONOCYTES AND MACROPHAGES MEDIATE ANTI-TNF REFRACTORY CROHN'S DISEASE IN CHILDREN by Geem, Duke, Maddipatla, Sushma, Pelia, Ranjit, Venkateswaran, Suresh, Matthews, Jason, Anbazhagan, Murugadas, Kolachala, Vasantha, Dodd, Anne, Kugathasan, Subra

“…Abstract BACKGROUND Crohn’s disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract with detrimental consequences on the pediatric…”
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Su1816 COMPARATIVE SINGLE-CELL RNA-SEQ ANALYSIS BETWEEN PATIENT-DERIVED MUCOSAL EPITHELIUM AND THEIR INTESTINAL ORGANOIDS by Murthy, Shanta, Maddipatia, Sushma C., Anbazhagan, Murugadas, Pelia, Ranjit S., Dodd, Ann, Kolachala, Vasantha, Geem, Duke, Cutler, David J., Matthews, Jason, Kugathasan, Subra

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Tu1759 ALTERED INFLAMMATORY MUCOSAL SIGNATURES WITHIN THEIR SPATIAL AND CELLULAR CONTEXT DURING ACTIVE, ILEAL CROHN'S DISEASE by Kolachala, Vasantha L., addip at la, Sushma C. M, Murthy, Shanta, Hwang, Yeonjoo, Dodd, Ann, Pelia, Ranjit S., Anbazhagan, Murugadas, Koti, Tarun, Yin, Hong, Lopez, Chrissy A., Cutler, David J., Qiu, Peng, Matthews, Jason, Kugathasan, Subra

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Su1562: PROFILING INFLAMED AND NON-INFLAMED CROHN'S DISEASE TISSUE USING SPATIAL TRANSCRIPTOMICS TO ANCHOR SINGLE CELL RNA-SEQ DATA REVEALING A CD74-MIF INTERACTION ACROSS MULTIPLE CELL TYPES by Kolachala, Vasantha, Maddipatia, Sushma C., Dodd, Ann, Pelia, Ranjit S., Venkateswaran, Suresh, Anbazhagan, Murugadas, Geem, Duke, yin, Julie, Qiu, Peng, Gibson, Greg, Matthews, Jason, Kugathasan, Subra

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Sa1590: RADIOGRAPHIC PROGRESSION AND THE EFFECT OF ANTI-TUMOR NECROSIS FACTOR IN CHILDREN WITH TREATMENT NAÏVE CROHN'S DISEASE by Scheel, Robert, Geem, Duke, Venkateswaran, Suresh, Pelia, Ranjit S., Alazraki, Adina, Dillman, Jonathan, Hyams, Jeffrey S., Denson, Lee A., Kugathasan, Subra

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Su1559: CELLULAR AND TRANSCRIPTIONAL DIVERSITY AMONGST CROHN'S DISEASE GROUPS BY SINGLE CELL TRANSCRIPTOMICS by Maddipatia, Sushma C., Kolachala, Vasantha, Venkateswaran, Suresh, Pelia, Ranjit S., Dodd, Ann, Anbazhagan, Murugadas, Geem, Duke, yin, Julie, Gibson, Greg, Matthews, Jason, Kugathasan, Subra, Qiu, Peng

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Tu1253 SINGLE CELL TRANSCRIPTOMIC ANALYSIS OF RECTAL HEALING PROFILES IN PERIANAL FISTULIZING CROHN'S DISEASE by Maddipatia, Sushma C., Murthy, Shanta, Dodd, Ann, Kolachala, Vasantha, Washburn, Savannah, Pelia, Ranjit S., Anbazhagan, Murugadas, Geem, Duke, Gibson, Greg, Qiu, Peng, Cutler, David J., Matthews, Jason, Kugathasan, Subra

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Su1563: GWAS OF INFLAMMATORY BOWEL DISEASE IN A SRI LANKAN POPULATION REVEALED DISTINCT AND SHARED IBD ALLELE ARCHITECTURE by Niriella, Madunil A., Venkateswaran, Suresh, Rajindrajith, Shaman, Kodisinghe, Kuleesha, Silva, Arjuna P. De, Silva, Hithanadura J. De, Yasara, Nirmani, Mettananda, Sachith, Pelia, Ranjit S., Gettler, Kyle, Cutler, David J., Cho, Judy H., Kugathasan, Subra

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Assessing Cellular and Transcriptional Diversity of Ileal Mucosa Among Treatment-Naïve and Treated Crohn’s Disease by Maddipatla, Sushma Chowdary, Kolachala, Vasantha L, Venkateswaran, Suresh, Dodd, Anne F, Pelia, Ranjit Singh, Geem, Duke, Yin, Hong, Sun, Yutong, Xu, Congmin, Mo, Angela, Kosters, Astrid, Yang, Junkai, Matthews, Jason D, Ghosn, Eliver, Kugathasan, Subra, Qiu, Peng

“…Abstract Background Crohn’s disease is a lifelong disease characterized by chronic inflammation of the gastrointestinal tract. Defining the cellular and…”
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Characterization of Intestinal Mesenchymal Stromal Cells From Patients With Inflammatory Bowel Disease for Autologous Cell Therapy by Anbazhagan, Murugadas, Geem, Duke, Venkateswaran, Suresh, Pelia, Ranjit, Kolachala, Vasantha L, Dodd, Anne, Maddipatla, Sushma C, Cutler, David J, Matthews, Jason D, Chinnadurai, Raghavan, Kugathasan, Subra

“…Therapy with mesenchymal stromal cells (MSCs) has shown promise in inflammatory bowel disease-leveraging their immunosuppressive and regenerative properties…”
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526: TIMING OF ANTI-TUMOR NECROSIS FACTOR ADMINISTRATION IMPACTS THE NATURAL HISTORY OF STRICTURING CROHN'S DISEASE IN CHILDREN by Geem, Duke, Hercules, David, Venkateswaran, Suresh, Pelia, Ranjit S., Hyams, Jeffrey S., Denson, Lee A., Kugathasan, Subra

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