Search Results - "Pelhate, M."

Peptides of arachnid venoms with insecticidal activity targeting sodium channels by De Lima, M.E., Figueiredo, S.G., Pimenta, A.M.C., Santos, D.M., Borges, M.H., Cordeiro, M.N., Richardson, M., Oliveira, L.C., Stankiewicz, M., Pelhate, M.

“…Arachnids have a venom apparatus and secrete a complex chemical mixture of low molecular mass organic molecules, enzymes and polypeptide neurotoxins designed…”
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Functional Expression and Genetic Alteration of an Alpha Scorpion Neurotoxin by Zilberberg, Noam, Gordon, Dalia, Pelhate, Marcel, Adams, Michael E, Norris, Timothy M, Zlotkin, Eliahu, Gurevitz, Michael

“…The alpha neurotoxin LqhαIT is toxic to both insects and mammals but exhibits a bioactivity ratio favoring insects (insect/mammal ∼2). With the objective of…”
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The toxin Tx4(6-1) from the spider Phoneutria nigriventer slows down Na + current inactivation in insect CNS via binding to receptor site 3 by de Lima, M.E, Stankiewicz, M, Hamon, A, de Figueiredo, S.G, Cordeiro, M.N, Diniz, C.R, Martin-Eauclaire, M.-F, Pelhate, M

“…Tx4(6-1) a neurotoxic peptide from the venom of the aggressive South American ‘armed’ spider Phoneutria nigriventer, has been previously isolated and…”
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Biophysical properties of scorpion α-toxin-sensitive background sodium channel contributing to the pacemaker activity in insect neurosecretory cells (DUM neurons) by Lapied, B., Stankiewicz, M., Grolleau, F., Rochat, H., Zlotkin, E., Pelhate, M.

“…A scorpion α‐toxin‐sensitive background sodium channel was characterized in short‐term cultured adult cockroach dorsal unpaired median (DUM) neurons using the…”
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A scorpion venom neurotoxin paralytic to insects that affects sodium current inactivation: purification, primary structure, and mode of action by Eitan, Michal, Fowler, Elizabeth, Herrmann, Rafael, Duval, Alain, Pelhate, Marcel, Zlotkin, Eliahu

“…A new toxin, Lqh alpha IT, which caused a unique mode of paralysis of blowfly larvae, was purified from the venom of the scorpion Leiurus quinquestriatus…”
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Primary structure and electrophysiological characterization of two almost identical isoforms of toxin from Isometrus vittatus (family: Buthidae) scorpion venom by Coronas, F.V, Stankiewicz, M, Batista, C.V.F, Giraud, S, Alam, J.M, Possani, L.D, Mebs, D, Pelhate, M

“…Two almost identical proteins with 70 amino acid residues each, closely packed by four disufide bridges, and molecular masses of 7899.5 and 7884.7 were…”
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Anatomy and targets of dorsal unpaired median neurones in the terminal abdominal ganglion of the male cockroach Periplaneta americana L by Sinakevitch, I.G., Geffard, M., Pelhate, M., Lapied, B.

“…The morphology of the Dorsal Unpaired Median (DUM) neurones in the Terminal Abdominal Ganglion (TAG) of the adult male cockroach Periplaneta americana were…”
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Insect background sodium channel as a new target for scorpion alpha toxin by Stankiewicz, Maria, Grolleau, Françoise, Rochat, Hervé, Zlotkin, Eliahu, Pelhate, Marcel, Lapied, Bruno

“…The effects of an anti‐insect scorpion alpha toxin, LqhαIT, isolated from the venom of the Israeli scorpion Leiurus quinquestriatus hebraeus was studied on…”
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Actions of insect toxin and other toxins derived from the venom of the scorpion Androctonus australis on isolated giant axons of the cockroach (Periplaneta americana) by Pelhate, M, Zlotkin, E

“…1. Insect toxin, mammal toxins I and II and crustacean toxin were obtained from the venom of the scorpion Androctonus australis. Their effects on the isolated…”
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Bot IT2, a toxin paralytic to insects from the Buthus occitanus tunetanus venom modifying the activity of insect sodium channels by Stankiewicz, M., Grolleau, F., Lapied, B., Borchani, L., El Ayeb, M., Pelhate, M.

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An excitatory and a depressant insect toxin from scorpion venom both affect sodium conductance and possess a common binding site by Zlotkin, E, Kadouri, D, Gordon, D, Pelhate, M, Martin, M F, Rochat, H

“…Two insect selective toxins were purified by gel-permeation and ion-exchange chromatographies from the venom of the scorpion, Leiurus quinquestriatus…”
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Octopaminergic dorsal unpaired median (DUM) neurones innervating the colleterial glands of the female cockroach Periplaneta americana by Sinakevitch, I, I, Geffard, M, Pelhate, M, Lapied, B

“…The musculature of the colleterial glands receives innervation from branch 4B4a of the nerves designated 4B, which arise from the posterior part of the…”
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Patch-clamp study of the properties of the sodium current in cockroach single isolated adult aminergic neurones by LAPIED, B, MALECOT, C. O, PELHATE, M

“…The properties of the fast Na+ inward current of the aminergic neurosecretory dorsal unpaired median (DUM) cells isolated from the sixth abdominal ganglion of…”
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Purification of two depressant insect neurotoxins and their gene cloning from the scorpion Buthus martensi Karsch by Wang, C-G., Ling, M-H., Chi, C-W., Wang, D-C., Stankiewicz, M., Pelhate, M.

“…:  Insect‐specific neurotoxins are important components of scorpion venoms. In this study, two toxins from the scorpion Buthus martensi Karsch (BmK) were…”
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A neosynthesis of sodium channels is involved in the evolution of the sodium current in isolated adult DUM neurons by TRIBUT, F, LAPIED, B, DUVAL, A, PELHATE, M

“…Short-term culture of isolated adult dorsal unpaired median (DUM) neurons of the cockroach Periplaneta americana has been used to study the evolution of the…”
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A Possible Explanation for a Neurotoxic Effect of the Anticancer Agent Oxaliplatin on Neuronal Voltage-Gated Sodium Channels by Grolleau, Francoise, Gamelin, Laurence, Boisdron-Celle, Michele, Lapied, Bruno, Pelhate, Marcel, Gamelin, Erick

“…  1 Laboratoire de Neurophysiologie Unité Propre de Recherche de l'Enseignement Supérieur Equipe d'Accueil (UPRES EA) 2647, Université d'Angers, Unité de…”
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Selective inhibition of potassium current in the giant axon of the cockroach by Pelhate, M, Pichon, Y

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A Recombinant Insect‐Specific α‐Toxin of Buthus occitanus tunetanus Scorpion Confers Protection Against Homologous Mammal Toxins by Bouhaouala‐Zahar, Balkiss, Ducancel, Frédérique, Zenouaki, Ilham, Khalifa, Rym, Borchani, Lamia, Pelhate, Marcel, Boulain, Jean‐Claude, Ayeb, Mohamed, Ménez, André, Karoui, Habib

“…We have constructed a cDNA library from venom glands of the scorpion Buthus occitanus tunetanus and cloned a DNA sequence that encodes an α‐toxin. This clone…”
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Action of calycanthine on nervous transmission in cockroach central nervous system by Adjibadé, Y, Hue, B, Pelhate, M, Anton, R

“…Calycanthine, the principal alkaloid of the order Calycanthaceae, has been isolated from a species of the genus Psychotria (Rubiaceae) occurring in some…”
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Structure-activity relationships of aminopyridines and derivates on axonal K+ conductance by Pelhate, M, Malécot, C O

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