Search Results - "Pelaprat, D"

Distribution, cellular localization and functional role of CCR2 chemokine receptors in adult rat brain by Banisadr, G., Quéraud‐Lesaux, F., Boutterin, M. C., Pélaprat, D., Zalc, B., Rostène, W., Haour, F., Mélik Parsadaniantz, S.

“…Recent studies demonstrated that the chemokine monocyte chemoattractant protein‐1 (MCP‐1)/CCL2 and its receptor, CCR2, play important roles in various brain…”
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Blockade of 12-lipoxygenase expression protects cortical neurons from apoptosis induced by beta-amyloid peptide by Lebeau, A, Terro, F, Rostene, W, Pelaprat, D

“…The cyclo-oxygenase (COX) and lipoxygenase (LOX) pathways belong to the eicosanoid synthesis pathway, a major component of the chronic inflammatory process…”
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Cellular distribution of neurotensin receptors in rat brain: Immunohistochemical study using an antipeptide antibody against the cloned high affinity receptor by Boudin, H., Pélaprat, D., Rostène, W., Beaudet, A.

“…Receptors for the neuropeptide, neurotensin, were localized by immunohistochemistry in the rat brain by using an antibody raised against a sequence of the…”
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Baicalein protects cortical neurons from β-amyloid (25-35) induced toxicity by Lebeau, Antony, Esclaire, Françoise, Rostène, William, Pélaprat, Didier

“…Accumulation of amyloid β peptide (Aβ) has been suggested to contribute to neurodegeneration in Alzheimer's disease (AD). Since chronic inflammation occurs in…”
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Correlative Ultrastructural Distribution of Neurotensin Receptor Proteins and Binding Sites in the Rat Substantia Nigra by Boudin, H, Pelaprat, D, Rostene, W, Pickel, V. M, Beaudet, A

“…Neurotensin (NT) produces various stimulatory effects on dopaminergic neurons of the rat substantia nigra. To gain insight into the subcellular substrate for…”
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High-affinity neurotensin receptors in the rat nucleus accumbens: Subcellular targeting and relation to endogenous ligand by Pickel, Virginia M., Chan, June, Delle Donne, Karen T., Boudin, Hèlène, Pélaprat, Didier, Rosténe, William

“…Neurotensin is present in selective mesolimbic dopaminergic projections to the nucleus accumbens (NAc) shell but also is synthesized locally in this region and…”
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In vivo and in vitro structure-activity studies with peptide and pseudopeptide neurotensin analogs suggest the existence of distinct central neurotensin receptor subtypes by Labbé-Jullié, C, Dubuc, I, Brouard, A, Doulut, S, Bourdel, E, Pelaprat, D, Mazella, J, Martinez, J, Rostène, W, Costentin, J

“…The present study was designed to compare, with respect to structure-activity relationships, the receptors that subserve the hypothermic and analgesic effects…”
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Characterization of binding sites of a new neurotensin receptor antagonist, [ [formula omitted]]SR 142948A, in the rat brain by Betancur, Catalina, Canton, Maryse, Burgos, Alain, Labeeuw, Bernard, Gully, Danielle, Rostène, William, Pélaprat, Didier

“…The present study describes the characterization of the binding properties and autoradiographic distribution of a new nonpeptide antagonist of neurotensin…”
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Interactions between neurotensin receptors and G proteins by Pelaprat, Didier

“…Three neurotensin (NT) receptors have been cloned to date, two of which, NTS1 and NTS2, belong to the family of seven transmembrane domain receptors coupled to…”
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Immunologic differentiation of two high-affinity neurotensin receptor isoforms in the developing rat brain by Boudin, Hélène, Lazaroff, Brigitte, Bachelet, Claude-Marie, Pélaprat, Didier, Rostène, William, Beaudet, Alain

“…Earlier studies have demonstrated overexpression of NT1 neurotensin receptors in rat brain during the first 2 weeks of life. To gain insight into this…”
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Characterization and distribution of binding sites for a new neurotensin receptor antagonist ligand, [3H]SR 48692, in the guinea pig brain by Betancur, C, Canton, M, Gully, D, Vela, G, Pélaprat, D, Rostène, W

“…SR 48692, a selective nonpeptide antagonist of neurotensin (NT) receptors was developed recently. In the present work we studied the binding properties of the…”
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Differential ontogenetic patterns of levocabastine-sensitive neurotensin NT2 receptors and of NT1 receptors in the rat brain revealed by in situ hybridization by Lépée-Lorgeoux, I, Betancur, C, Rostène, W, Pélaprat, D

“…The postnatal ontogeny of the levocabastine-sensitive neurotensin receptor (NT2) mRNA was studied by in situ hybridization in the rat brain and compared with…”
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Evidence for neurotensin autoreceptors and relationship of neurotensin and its receptors with tyrosine hydroxylase-positive neurons in rat primary hypothalamic cultures by Bachelet, C M, Scarcériaux, V, Rostène, W, Pélaprat, D

“…Neurotensin is present in high quantity in the hypothalamus, where it regulates pituitary hormone secretion. A relationship between dopaminergic and…”
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Cyclic Cholecystokinin Analogues with High Selectivity for Central Receptors by Charpentier, Bruno, Pelaprat, Didier, Durieux, Christiane, Dor, Adeline, Reibaud, Michel, Blanchard, Jean-Charles, Roques, Bernard P.

“…Taking as a model the N-terminal folding of the cholecystokinin tyrosine-sulfated octapeptide [CCK-8; Asp-Tyr-(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH$_{2}$] deduced…”
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Neurotensin receptor down-regulation induced by dexamethasone and forskolin in rat hypothalamic cultures is mediated by endogenous neurotensin by Scarcériaux, V, Souazé, F, Bachelet, C M, Forgez, P, Bourdel, E, Martinez, J, Rostène, W, Pélaprat, D

“…Neurotensin (NT) has been shown to be involved in neuroendocrine regulation, and the presence of both the peptide and its receptors has been demonstrated in…”
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Immunological recognition of different forms of the neurotensin receptor in transfected cells and rat brain by Boudin, H, Grauz-Guyon, A, Faure, M P, Forgez, P, Lhiaubet, A M, Dennis, M, Beaudet, A, Rostene, W, Pelaprat, D

“…In this work, the molecular forms of the rat neurotensin receptor (NTR) expressed in transfected Chinese hamster ovary (CHO) cells, in infected Sf9 insect…”
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Neurotensin receptor interaction with dopaminergic systems in the guinea-pig brain shown by neurotensin receptor antagonists by Azzi, M, Gully, D, Heaulme, M, Bérod, A, Pélaprat, D, Kitabgi, P, Boigegrain, R, Maffrand, J P, LeFur, G, Rostène, W

“…Neurotensin has been suggested to be involved in neurological and mental disorders associated with altered dopaminergic transmission. The lack of a potent…”
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In-vitro development of corneal epithelial cells on a new hydrogel for epikeratoplasty by Maury, F, Honiger, J, Pelaprat, D, Baudrimont, M, Borderie, V, Rostene, W, Laroche, L

“…This study demonstrates the adhesion and growth of bovine corneal epithelial cells on the surface of a new hydrogel. The hydrogel, containing 78% of water and…”
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Steroid effects on brain functions : an example of the action of glucocorticoids on central dopaminergic and neurotensinergic systems by ROSTENE, W, SARRIEAU, A, BEROD, A, NICOT, A, SCARCERIAUX, V, BETANCUR, C, GULLY, D, MEANEY, M, ROWE, W, DE KLOET, R, PELAPRAT, D

“…It is now clearly established that steroid hormones released from peripheral endocrine glands may, through specific receptors in the brain, directly regulate…”
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Pharmacological and molecular characterization of the neurotensin receptor expressed in Sf9 cells by Boudin, Hélène, Labrecque, Jean, Lhiaubet, Anne-Marie, Dennis, Michael, Rostène, William, Pélaprat, Didier

“…The rat neurotensin receptor was expressed in Spodoptera frugiperda insect (Sf9) cells using infection with a recombinant baculovirus. Immunoblot experiments…”
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