Search Results - "Pelageev, Dmitry"

Dimeric (Poly)Hydroxynaphthazarins, Metabolites of Echinoderms and Lichens: The History of the Synthesis and Structure Elucidation by Pelageev, Dmitry N, Borisova, Ksenia L, Anufriev, Victor Ph

“…This review provides information on the synthesis and revision of the structures of natural dimeric (poly)hydroxynaphthazarins, metabolites of echinoderms and…”
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Neuroprotective Effect of 1,4-Naphthoquinones in an In Vitro Model of Paraquat and 6-OHDA-Induced Neurotoxicity by Menchinskaya, Ekaterina, Chingizova, Ekaterina, Pislyagin, Evgeny, Likhatskaya, Galina, Sabutski, Yuri, Pelageev, Dmitry, Polonik, Sergei, Aminin, Dmitry

“…Targeted screening using the MTT cell viability test with a mini-library of natural and synthetic 1,4-naphthoquinones and their derivatives was performed in…”
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New Marine Fungal Deoxy-14,15-Dehydroisoaustamide Resensitizes Prostate Cancer Cells to Enzalutamide by Dyshlovoy, Sergey A, Zhuravleva, Olesya I, Hauschild, Jessica, Busenbender, Tobias, Pelageev, Dmitry N, Yurchenko, Anton N, Khudyakova, Yuliya V, Antonov, Alexandr S, Graefen, Markus, Bokemeyer, Carsten, von Amsberg, Gunhild

“…Marine fungi serve as a valuable source for new bioactive molecules bearing various biological activities. In this study, we report on the isolation of a new…”
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Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer by Dyshlovoy, Sergey A, Pelageev, Dmitry N, Hauschild, Jessica, Sabutskii, Yurii E, Khmelevskaya, Ekaterina A, Krisp, Christoph, Kaune, Moritz, Venz, Simone, Borisova, Ksenia L, Busenbender, Tobias, Denisenko, Vladimir A, Schlüter, Hartmut, Bokemeyer, Carsten, Graefen, Markus, Polonik, Sergey G, Anufriev, Victor Ph, Amsberg, Gunhild von

“…The phenomenon of high sugar consumption by tumor cells is known as Warburg effect. It results from a high glycolysis rate, used by tumors as preferred…”
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Synthesis, Cytotoxic Activity Evaluation and Quantitative Structure-ActivityAnalysis of Substituted 5,8-Dihydroxy-1,4-naphthoquinones and Their O- and S-Glycoside Derivatives Tested against Neuro-2a Cancer Cells by Polonik, Sergey, Likhatskaya, Galina, Sabutski, Yuri, Pelageev, Dmitry, Denisenko, Vladimir, Pislyagin, Evgeny, Chingizova, Ekaterina, Menchinskaya, Ekaterina, Aminin, Dmitry

“…Based on 6,7-substituted 2,5,8-trihydroxy-1,4-naphtoquinones (1,4-NQs) derived from sea urchins, five new acetyl-O-glucosides of NQs were prepared. A new…”
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Activity of New Synthetic (2-Chloroethylthio)-1,4-naphthoquinones in Prostate Cancer Cells by Dyshlovoy, Sergey A., Pelageev, Dmitry N., Jakob, Lea S., Borisova, Ksenia L., Hauschild, Jessica, Busenbender, Tobias, Kaune, Moritz, Khmelevskaya, Ekaterina A., Graefen, Markus, Bokemeyer, Carsten, Anufriev, Victor Ph, von Amsberg, Gunhild

“…Development of resistance to currently available standard therapies in advanced prostate cancer (PCa) emphasizes the need for novel therapeutic options. Here,…”
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Successful Targeting of the Warburg Effect in Prostate Cancer by Glucose-Conjugated 1,4-Naphthoquinones by Dyshlovoy, Sergey A, Pelageev, Dmitry N, Hauschild, Jessica, Borisova, Ksenia L, Kaune, Moritz, Krisp, Christoph, Venz, Simone, Sabutskii, Yurii E, Khmelevskaya, Ekaterina A, Busenbender, Tobias, Denisenko, Vladimir A, Pokhilo, Natalia D, Atopkina, Lyubov N, Graefen, Markus, Schlüter, Hartmut, Stonik, Valentin A, Bokemeyer, Carsten, Anufriev, Victor Ph, von Amsberg, Gunhild

“…Treatment of castration-resistant prostate cancer (CRPC) remains challenging due to the development of drug resistance. The Warburg effect describes the…”
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Quinone–carbohydrate nonglucoside conjugates as a new type of cytotoxic agents: Synthesis and determination of in vitro activity by Pelageev, Dmitry N., Dyshlovoy, Sergey A., Pokhilo, Nataly D., Denisenko, Vladimir A., Borisova, Ksenia L., Keller-von Amsberg, Gunhild, Bokemeyer, Carsten, Fedorov, Sergey N., Honecker, Friedemann, Anufriev, Victor Ph

“…We have found that 2-methoxy-1,4-naphthoquinones easily react with primary alcohols to produce the corresponding 2-alkoxyderivatives. Using this reaction, we…”
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New Antibacterial Chloro-Containing Polyketides from the Alga-Derived Fungus Asteromyces cruciatus KMM 4696 by Zhuravleva, Olesya I, Oleinikova, Galina K, Antonov, Alexandr S, Kirichuk, Natalia N, Pelageev, Dmitry N, Rasin, Anton B, Menshov, Alexander S, Popov, Roman S, Kim, Natalya Yu, Chingizova, Ekaterina A, Chingizov, Artur R, Volchkova, Olga O, von Amsberg, Gunhild, Dyshlovoy, Sergey A, Yurchenko, Ekaterina A, Guzhova, Irina V, Yurchenko, Anton N

“…Six new polyketides acrucipentyns A-F ( - ) were isolated from the alga-derived fungus KMM 4696. Their structures were established based on spectroscopic…”
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Concerning the structure of islandoquinone isolated from the lichen Cetraria islandica by Borisova, Ksenia L, Pelageev, Dmitry N, Kochergina, Tatiana Yu, Pokhilo, Nataly D, Pushilin, Michael A, Denisenko, Vladimir A, Berdyshev, Dmitry V, Anufriev, Victor Ph

“…An investigation of the oxidative coupling products of some substituted hydroxynaphthazarins led to a revision of the proposed structure of islandoquinone,…”
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A convenient synthetic approach to dioncoquinone B and related compounds by Khmelevskaya, Ekaterina A., Pelageev, Dmitry N.

“…[Display omitted] •Gram-scale synthesis.•Available inexpensive reagents.•Simple techniques. A total synthesis of dioncoquinone B and related compounds,…”
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A simple synthesis of natural spinazarins and their analogues by Pelageev, Dmitry N., Borisova, Ksenia L., Kovach, Svetlana M., Makhankov, Vyacheslav V., Anufriev, Victor Ph

“…[Display omitted] A short simple synthesis of spinazarins (2,3-dihydroxy-naphthazarins or 2,3,5,8-tetrahydroxy-1,4-naphtho-quinones) from available…”
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In vitro and in vivo investigations of novel 1,4-napthoquinone sulphomethylene carbohydrate conjugates in prostate cancer by Busenbender, Tobias, Dyshlovoy, Sergey, Kaune, Moritz, Boeckelmann, Lukas, Lange, Tobias, Schumacher, Udo, Pelageev, Dmitry N, Sabutskii, Yurii E, Borisova, Ksenia, Anufriev, Victor Ph, Graefen, Markus, Bokemeyer, Carsten, Von Amsberg, Gunhild

“…Abstract only 104 Background: The Warburg effect describes the ability of cancer cells to consume larger amounts of glucose in comparison to normal tissue, due…”
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Synthesis, Cytotoxic Activity Evaluation and Quantitative Structure-Activity Analysis of Substituted 5,8-Dihydroxy-1,4-Naphthoquinones and their O - and S -Glycoside Derivatives Tested Against Neuro-2a Cancer Cells by Polonik, Sergey, Likhatskaya, Galina, Sabutski, Yuri, Pelageev, Dmitry, Denisenko, Vladimir, Pislyagin, Evgeny, Chingizova, Ekaterina, Menchinskaya, Ekaterina, Aminin, Dmitry

“…Based on 6,7-substituted 2,5,8-trihydroxy-1,4-naphtoquinones (1,4-NQs) derived from sea urchins, five new acetyl- -glucosides of NQs were prepared. A new…”
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