Search Results - "Pejoski, David"

Vaccine Inoculation Route Modulates Early Immunity and Consequently Antigen-Specific Immune Response by Rosenbaum, Pierre, Tchitchek, Nicolas, Joly, Candie, Rodriguez Pozo, André, Stimmer, Lev, Langlois, Sébastien, Hocini, Hakim, Gosse, Leslie, Pejoski, David, Cosma, Antonio, Beignon, Anne-Sophie, Dereuddre-Bosquet, Nathalie, Levy, Yves, Le Grand, Roger, Martinon, Frédéric

“…Vaccination is one of the most efficient public healthcare measures to fight infectious diseases. Nevertheless, the immune mechanisms induced by vaccination…”
Get full text

SPADEVizR: an R package for visualization, analysis and integration of SPADE results by Gautreau, Guillaume, Pejoski, David, Le Grand, Roger, Cosma, Antonio, Beignon, Anne-Sophie, Tchitchek, Nicolas

“…Flow, hyperspectral and mass cytometry are experimental techniques measuring cell marker expressions at the single cell level. The recent increase of the…”
Get full text

The combination of ISCOMATRIX adjuvant and TLR agonists induces regression of established solid tumors in vivo by Silva, Anabel, Mount, Adele, Krstevska, Karoline, Pejoski, David, Hardy, Matthew P, Owczarek, Catherine, Scotney, Pierre, Maraskovsky, Eugene, Baz Morelli, Adriana

“…The development of therapeutic vaccines for treatment of established cancer has proven challenging. Cancer vaccines not only need to induce a robust tumor…”
Get full text

Identification of Vaccine-Altered Circulating B Cell Phenotypes Using Mass Cytometry and a Two-Step Clustering Analysis by Pejoski, David, Tchitchek, Nicolas, Rodriguez Pozo, André, Elhmouzi-Younes, Jamila, Yousfi-Bogniaho, Rahima, Rogez-Kreuz, Christine, Clayette, Pascal, Dereuddre-Bosquet, Nathalie, Lévy, Yves, Cosma, Antonio, Le Grand, Roger, Beignon, Anne-Sophie

“…Broadening our understanding of the abundance and phenotype of B cell subsets that are induced or perturbed by exogenous Ags will improve the vaccine…”
Get full text

Site-Specific DC Surface Signatures Influence CD4 + T Cell Co-stimulation and Lung-Homing by Pejoski, David, Ballester, Marie, Auderset, Floriane, Vono, Maria, Christensen, Dennis, Andersen, Peter, Lambert, Paul-Henri, Siegrist, Claire-Anne

“…Dendritic cells (DCs) that drain the gut and skin are known to favor the establishment of T cell populations that home to the original site of DC-antigen (Ag)…”
Get full text

C-type lectin receptor agonists elicit functional IL21-expressing Tfh cells and induce primary B cell responses in neonates by Vono, Maria, Mastelic-Gavillet, Beatris, Mohr, Elodie, Östensson, Malin, Persson, Josefine, Olafsdottir, Thorunn A, Lemeille, Sylvain, Pejoski, David, Hartley, Oliver, Christensen, Dennis, Andersen, Peter, Didierlaurent, Arnaud M, Harandi, Ali M, Lambert, Paul-Henri, Siegrist, Claire-Anne

“…C-type lectin receptor (CLR) agonists emerged as superior inducers of primary B cell responses in early life compared with Toll-like receptor (TLR) agonists,…”
Get full text

Corrigendum: Site-Specific DC Surface Signatures Influence CD4 + T Cell Co-stimulation and Lung-Homing by Pejoski, David, Ballester, Marie, Auderset, Floriane, Vono, Maria, Christensen, Dennis, Andersen, Peter, Lambert, Paul-Henri, Siegrist, Claire-Anne

“…[This corrects the article DOI: 10.3389/fimmu.2019.01650.]…”
Get full text

Global blood miRNA profiling unravels early signatures of immunogenicity of Ebola vaccine rVSVΔG-ZEBOV-GP by Vianello, Eleonora, Persson, Josefine, Andersson, Björn, van Veen, Suzanne, Dias, Thomaz Lüscher, Santoro, Francesco, Östensson, Malin, Obudulu, Ogonna, Agbajogu, Christopher, Torkzadeh, Sara, Agnandji, Selidji Todagbe, Ahmed, Rafi, Anderson, Jenna, Auderset, Floriane, Bejon, Philip, Borgianni, Luisa, Brosnahan, Jessica, Ciabattini, Annalisa, Engler, Olivier, Haks, Marielle C., Harandi, Ali M., Heppner, Donald Gray, Gerlini, Alice, Huttner, Angela, Kremsner, Peter G., Medaglini, Donata, Monath, Thomas, Ndungu, Francis, Njuguna, Patricia, Ottenhoff, Tom H.M., Pejoski, David, Page, Mark, Pozzi, Gianni, Santoro, Francesco, Siegrist, Claire-Anne, Dubey, Sheri, Eichberg, Micheal J., Gonzalez-Dias, Patrícia, Essone, Paulin Ndong, Kabwende, Lumeka, Kremsner, Peter Gottfried, Nakaya, Helder, Nakka, Sravya S., Haks, Mariëlle C., Persson, Josefine, Rothenberger, Sylvia, van Veen, Suzanne, Vianello, Eleonora, Nakaya, Helder I., Medaglini, Donata, Siegrist, Claire-Anne, Ottenhoff, Tom H.M., Harandi, Ali M.

“…The vectored Ebola vaccine rVSVΔG-ZEBOV-GP elicits protection against Ebola Virus Disease (EVD). In a study of forty-eight healthy adult volunteers who…”
Get full text

Transcriptomic signatures induced by the Ebola virus vaccine rVSVΔG-ZEBOV-GP in adult cohorts in Europe, Africa, and North America: a molecular biomarker study by Vianello, Eleonora, Gonzalez-Dias, Patricia, van Veen, Suzanne, Engele, Carmen G, Quinten, Edwin, Monath, Thomas P, Medaglini, Donata, Agnandij, Selidij T, Ahmed, Rafi, Anderson, Jenna, Auderset, Floriane, Bejon, Philip, Borgianni, Luisa, Brosnahan, Jessica, Ciabattini, Annalisa, Engler, Olivier, Haks, Mariëlle C, Harandi, Ali M, Heppner, Donald G, Gerlini, Alice, Huttner, Angela, Kremsner, Peter G, Medaglini, Donata, Monath, Thomas P, Ndungu, Francis M, Njuguna, Patricia, Ottenhoff, Tom H M, Pejoski, David, Page, Mark, Pozzi, Gianni, Santoro, Francesco, Siegrist, Claire-Anne, Dubey, Sheri, Eichberg, Michael, Ndong, Essone P, Lumeka, Kabwende, Nakaya, Helder I, Gonzales Dias Carvalho, Patricia, Rothenberger, Sylvia, Vianello, Eleonora, Nakka, Sravya S, van Veen, Suzanne, Santoro, Francesco, Huttner, Angela, Dubey, Sheri, Eichberg, Michael, Ndungu, Francis M, Kremsner, Peter G, Essone, Paulin N, Agnandji, Selidji Todagbe, Siegrist, Claire-Anne, Nakaya, Helder I, Ottenhoff, Tom H M, Haks, Mariëlle C

“…A recombinant vesicular stomatitis virus vector expressing the Zaire Ebola virus glycoprotein (rVSVΔG-ZEBOV-GP) vaccine has been reported as safe, immunogenic,…”
Get full text

A computational approach for phenotypic comparisons of cell populations in high-dimensional cytometry data by Platon, Ludovic, Pejoski, David, Gautreau, Guillaume, Targat, Brice, Le Grand, Roger, Beignon, Anne-Sophie, Tchitchek, Nicolas

“…•CytoCompare is an R package to compare the phenotypes of cytometry cell clusters.•A distance measure and a p-value is computed for each comparison of two…”
Get full text

Antibody responses to recombinant vesicular stomatitis virus-Zaire Ebolavirus vaccination for Ebola virus disease across doses and continents: 5-year durability by Huttner, Angela, Agnandji, Selidji Todagbe, Engler, Olivier, Hooper, Jay W, Kwilas, Steve, Ricks, Keersten, Clements, Tamara L, Jonsdottir, Hulda R, Nakka, Sravya Sowdamini, Rothenberger, Sylvia, Kremsner, Peter, Züst, Roland, Medaglini, Donata, Ottenhoff, Tom, Harandi, Ali M, Siegrist, Claire-Anne

“…To report 5-year persistence and avidity of antibodies produced by the live-attenuated recombinant vesicular stomatitis virus (rVSV) expressing the Zaire…”
Get more information

Vaccine Inoculation Route Modulates Early Immunity and Consequently Antigen-Specific Immune Response by Rosenbaum, Pierre, Tchitchek, Nicolas, Joly, Candie, Rodriguez Pozo, André, Stimmer, Lev, Langlois, Sébastien, Hocini, Hakim, Gosse, Leslie, Pejoski, David, Cosma, Antonio, Beignon, Anne-Sophie, Dereuddre-Bosquet, Nathalie, Levy, Yves, Le Grand, Roger, Martinon, Frédéric

“…Vaccination is one of the most efficient public healthcare measures to fight infectious diseases. Nevertheless, the immune mechanisms induced in vivo by…”
Get full text

Soluble proteins induce strong CD8+ T cell and antibody responses through electrostatic association with simple cationic or anionic lipopeptides that target TLR2 by Chua, Brendon Y, Pejoski, David, Turner, Stephen J, Zeng, Weiguang, Jackson, David C

“…The low immunogenicity exhibited by most soluble proteins is generally due to the absence of molecular signatures that are recognized by the immune system as…”
Get full text

A lipopeptide based on the M2 and HA proteins of influenza A viruses induces protective antibody by Pejoski, David, Zeng, Weiguang, Rockman, Steven, Brown, Lorena E, Jackson, David C

“…A conserved 15 amino‐acid residue sequence of the ectodomain of the M2 protein of influenza A virus (M2e) induces a strong antibody (Ab) response when…”
Get full text

Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination by Pejoski, David, de Rham, Casimir, Martinez-Murillo, Paola, Santoro, Francesco, Auderset, Floriane, Medaglini, Donata, Pozzi, Gianni, Vono, Maria, Lambert, Paul-Henri, Huttner, Angela, Haks, Mariëlle C., Ottenhoff, Tom H. M., Villard, Jean, Siegrist, Claire-Anne

“…The rVSV-ZEBOV Ebolavirus vaccine confers protection within days after immunization, suggesting the contribution of innate immune responses. We report…”
Get full text

Erratum: Author Correction: Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination by Pejoski, David, de Rham, Casimir, Martinez-Murillo, Paola, Santoro, Francesco, Auderset, Floriane, Medaglini, Donata, Pozzi, Gianni, Vono, Maria, Lambert, Paul-Henri, Huttner, Angela, Haks, Mariëlle C, Ottenhoff, Tom H M, Villard, Jean, Siegrist, Claire-Anne

Get full text

Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination by Pejoski, David, de Rham, Casimir, Martinez-Murillo, Paola, Santoro, Francesco, Auderset, Floriane, Medaglini, Donata, Pozzi, Gianni, Vono, Maria, Lambert, Paul-Henri, Huttner, Angela, Haks, Mariëlle C, Ottenhoff, Tom H M, Villard, Jean, Siegrist, Claire-Anne

“…The rVSV-ZEBOV Ebolavirus vaccine confers protection within days after immunization, suggesting the contribution of innate immune responses. We report…”
Get full text

Author Correction: Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination by Pejoski, David, de Rham, Casimir, Martinez-Murillo, Paola, Santoro, Francesco, Auderset, Floriane, Medaglini, Donata, Pozzi, Gianni, Vono, Maria, Lambert, Paul-Henri, Huttner, Angela, Haks, Mariëlle C., Ottenhoff, Tom H. M., Villard, Jean, Siegrist, Claire-Anne

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text

Electrostatic-mediated enhancement of protein antigen immunogenicity using charged TLR2-targeting lipopeptides by Chua, Brendon Y., Pejoski, David, Turner, Stephen J., Zeng, Weiguang, Jackson, David C.

“…The low immunogenicities exhibited by most soluble proteins are in general due to the absence of any molecular signatures that are recognized by the immune…”
Get full text