Search Results - "Peixoto, Philippe A."

Asymmetric Hydroxylative Phenol Dearomatization Promoted by Chiral Binaphthylic and Biphenylic Iodanes by Bosset, Cyril, Coffinier, Romain, Peixoto, Philippe A., El Assal, Mourad, Miqueu, Karinne, Sotiropoulos, Jean-Marc, Pouységu, Laurent, Quideau, Stéphane

“…The long‐standing quest for chiral hypervalent organoiodine compounds (i.e., iodanes) as metal‐free reagents for asymmetric synthesis continues. Although…”
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Bioinspired Total Synthesis of (−)‐Vescalin: A Nonahydroxytriphenoylated C‐Glucosidic Ellagitannin by Richieu, Antoine, Peixoto, Philippe A., Pouységu, Laurent, Deffieux, Denis, Quideau, Stéphane

“…The first total synthesis of the 2,3,5‐O‐(S,R)‐nonahydroxytriphenoylated (NHTP) C‐glucosidic ellagitannin (−)‐vescalin was accomplished through a series of…”
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Flexible Total Synthesis of (±)-Aureothin, a Potent Antiproliferative Agent by Henrot, Matthias, Jean, Alexandre, Peixoto, Philippe A, Maddaluno, Jacques, De Paolis, Michaël

“…Amenable to late-stage preparation of analogues, a flexible and convergent total synthesis of (±)-aureothin is presented. The strategy was based on a…”
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Total Synthesis of (−)-Bacchopetiolone via an Asymmetric Hydroxylative Phenol Dearomatization/[4+2]-Dimerization Cascade Promoted by a Novel Salen-Type Chiral Iodane by Coffinier, Romain, Assal, Mourad El, Peixoto, Philippe A, Bosset, Cyril, Miqueu, Karinne, Sotiropoulos, Jean-Marc, Pouységu, Laurent, Quideau, Stéphane

“…The first total and biomimetic synthesis of the natural bis­(sesquiterpene) (−)-bacchopetiolone (revised structure) was completed through a highly…”
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ortho-Quinol Acetate Chemistry: Reactivity toward Aryl-Based Nucleophiles and Applications to the Synthesis of Natural Products by Companys, Simon, Pouységu, Laurent, Peixoto, Philippe A, Chassaing, Stefan, Quideau, Stéphane

“…Two model ortho-quinol acetates were easily prepared by iodane-mediated acetoxylative phenol dearomatization and evaluated for their reactivity toward various…”
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Bioinspired Total Synthesis of (−)‐Vescalin: A Nonahydroxytriphenoylated C‐Glucosidic Ellagitannin by Richieu, Antoine, Peixoto, Philippe A., Pouységu, Laurent, Deffieux, Denis, Quideau, Stéphane

“…The first total synthesis of the 2,3,5‐O‐(S,R)‐nonahydroxytriphenoylated (NHTP) C‐glucosidic ellagitannin (−)‐vescalin was accomplished through a series of…”
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Bispericyclic Diels–Alder Dimerization of ortho‐Quinols in Natural Product (Bio)Synthesis: Bioinspired Chemical 6‐Step Synthesis of (+)‐Maytenone by Peixoto, Philippe A., El Assal, Mourad, Chataigner, Isabelle, Castet, Frédéric, Cornu, Anaëlle, Coffinier, Romain, Bosset, Cyril, Deffieux, Denis, Pouységu, Laurent, Quideau, Stéphane

“…Many natural products of plant or microbial origins are derived from enzymatic dearomative oxygenation of 2‐alkylphenolic precursors into…”
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Blue LED Irradiation of Iodonium Ylides Gives Diradical Intermediates for Efficient Metal‐free Cyclopropanation with Alkenes by Chidley, Tristan, Jameel, Islam, Rizwan, Shafa, Peixoto, Philippe A., Pouységu, Laurent, Quideau, Stéphane, Hopkins, W. Scott, Murphy, Graham K.

“…A facile and highly chemoselective synthesis of doubly activated cyclopropanes is reported where mixtures of alkenes and β‐dicarbonyl‐derived iodonium ylides…”
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Synthesis of [7]Helicene Enantiomers and Exploratory Study of Their Conversion into Helically Chiral Iodoarenes and Iodanes by Antien, Kevin, Pouységu, Laurent, Deffieux, Denis, Massip, Stéphane, Peixoto, Philippe A., Quideau, Stéphane

“…The facile and convenient preparation of both enantiomers of a [7]helicene scaffold from inexpensive (l)‐(+)‐tartaric acid and 4‐methylstyrene is described…”
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Asymmetric Allenylation of Alkynes mediated by Chiral Organoselenated Reagents under Oxidative Conditions by Sun, Rongyu, Viaud, Emilie, Nomula, Rajesh, Naubron, Jean‐Valère, Daugey, Nicolas, Buffeteau, Thierry, Castet, Frédéric, Toullec, Patrick Y., Quideau, Stéphane, Peixoto, Philippe A.

“…Abstract The reactivity of novel chiral lactamide‐substituted diselenide‐based reagents under oxidative conditions was exploited to develop a metal‐free method…”
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Bio‐inspired Total Synthesis of Twelve Securinega Alkaloids: Structural Reassignments of (+)‐Virosine B and (−)‐Episecurinol A by Antien, Kevin, Lacambra, Aitor, Cossío, Fernando P., Massip, Stéphane, Deffieux, Denis, Pouységu, Laurent, Peixoto, Philippe A., Quideau, Stéphane

“…The so‐called Securinega alkaloids constitute a class of tetracyclic biologically active specialised metabolites isolated principally from subtropical plants…”
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Asymmetric Alkynylation of β‐Ketoesters and Naphthols Promoted by New Chiral Biphenylic Iodanes by Companys, Simon, Peixoto, Philippe A., Bosset, Cyril, Chassaing, Stefan, Miqueu, Karinne, Sotiropoulos, Jean‐Marc, Pouységu, Laurent, Quideau, Stéphane

“…The preparation of new chiral biphenylic λ3‐iodane reagents bearing transferable alkynyl ligands is described. These reagents transfer their carbon‐based…”
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Design and Synthesis of Epicocconone Analogues with Improved Fluorescence Properties by Peixoto, Philippe A, Boulangé, Agathe, Ball, Malcolm, Naudin, Bertrand, Alle, Thibault, Cosette, Pascal, Karuso, Peter, Franck, Xavier

“…Epicocconone is a natural latent fluorophore that is widely used in biotechnology because of its large Stokes shift and lack of fluorescence in its…”
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Synthesis of Scyphostatin Analogues through Hypervalent Iodine-Mediated Phenol Dearomatization by El Assal, Mourad, Peixoto, Philippe A, Coffinier, Romain, Garnier, Tony, Deffieux, Denis, Miqueu, Karinne, Sotiropoulos, Jean-Marc, Pouységu, Laurent, Quideau, Stéphane

“…A concise synthesis of two scyphostatin analogues is achieved from readily available ortho-substituted phenols. Key features include an asymmetric and…”
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Phenol Dearomatization with Hypervalent Iodine Reagents by Quideau, Stéphane, Pouységu, Laurent, Peixoto, Philippe A, Deffieux, Denis

“…This chapter highlights recent developments in phenol dearomatization using organoiodane reagents and a selection of applications in natural product synthesis…”
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Back Cover: Epicocconone–Hemicyanine Hybrids: Near Infrared Fluorophores for Protein Staining and Cell Imaging (Chem. Eur. J. 8/2017) by Karuso, Peter, Loa Kum Cheung, Wendy, Peixoto, Philippe A., Boulangé, Agathe, Franck, Xavier

“…The design, synthesis and characterization of a new family of long Stokes’ shift near infrared (NIR) fluorescent dyes obtained by hybridizing epicocconone and…”
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Diastereoselective IBX Oxidative Dearomatization of Phenols by Remote Induction: Towards the Epicocconone Core Framework by Boulangé, Agathe, Peixoto, Philippe A., Franck, Xavier

“…The IBX twist does it: Towards the synthesis of a recently isolated dihydropyranic azaphilone core framework, a 2‐iodoxybenzoic acid (IBX)‐mediated oxidative…”
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Asymmetric Hydroxylative Phenol Dearomatization Promoted by Chiral Binaphthylic and Biphenylic Iodanes by Bosset, Cyril, Coffinier, Romain, Peixoto, Philippe A., El Assal, Mourad, Miqueu, Karinne, Sotiropoulos, Jean-Marc, Pouységu, Laurent, Quideau, Stéphane

“…The long‐standing quest for chiral hypervalent organoiodine compounds (i.e., iodanes) as metal‐free reagents for asymmetric synthesis continues. Although…”
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The Role of Different Structural Motifs in the Ultrafast Dynamics of Second Generation Protein Stains by Chatterjee, Soumit, Karuso, Peter, Boulangé, Agathe, Peixoto, Philippe A, Franck, Xavier, Datta, Anindya

“…Engineering the properties of fluorescent probes through modifications of the fluorophore structure has become a subject of interest in recent times. By doing…”
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Formal Enantioselective Synthesis of Aplykurodinone-1 by Peixoto, Philippe A., Jean, Alexandre, Maddaluno, Jacques, De Paolis, Michaël

“…Step economy and simplicity were combined in the asymmetric formal synthesis of aplykurodinone‐1 (see scheme; TBS=tert‐butyldimethylsilyl). The key features of…”
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