Search Results - "Peinado, H."
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In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells
Published in Nature communications (08-10-2020)“…Fusion oncogenes (FOs) are common in many cancer types and are powerful drivers of tumor development. Because their expression is exclusive to cancer cells and…”
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Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization
Published in Oncogene (19-02-2015)“…Epithelial–mesenchymal transition (EMT) has been associated with increased aggressiveness and acquisition of migratory properties providing tumor cells with…”
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Polyethylene glycol improves current methods for circulating extracellular vesicle-derived DNA isolation
Published in Journal of translational medicine (11-03-2019)“…Extracellular vesicles (EVs) are small membrane-bound vesicles which play an important role in cell-to-cell communication. Their molecular cargo analysis is…”
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Snail silencing effectively suppresses tumour growth and invasiveness
Published in Oncogene (22-03-2007)“…The transcription factor Snail has been recently proposed as an important mediator of tumour invasion because of its role in downregulation of E-cadherin and…”
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The new deal: a potential role for secreted vesicles in innate immunity and tumor progression
Published in Frontiers in immunology (2015)“…Tumors must evade the immune system to survive and metastasize, although the mechanisms that lead to tumor immunoediting and their evasion of immune…”
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Mast cells and exosomes in hyperoxia-induced neonatal lung disease
Published in American journal of physiology. Lung cellular and molecular physiology (01-06-2016)“…Chronic lung disease of prematurity (CLD) is a frequent sequela of premature birth and oxygen toxicity is a major associated risk factor. Impaired…”
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Human prostasomes from normozoospermic and non‐normozoospermic men show a differential protein expression pattern
Published in Andrology (Oxford) (01-07-2018)“…Summary Prostasomes are exosomes such as extracellular vesicles, produced in the prostatic epithelium and released into the seminal plasma, that play an…”
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ΔNp73 and Δ133p53 in liquid biopsy as early diagnostic markers for colorectal cancer
Published in Annals of oncology (01-07-2019)Get full text
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Electrical percolation and fluidity of conductive recycled mortar cement: graphite powder: recycled sand with addition of industrial waste carbon fiber
Published in Carbon Letters (01-08-2021)“…The use of recycled materials, such as the fine recycled aggregate made from concrete waste and carbon fiber (CF) product of industrial waste, for the…”
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A spotlight on cancer researchers in Spain: new paradigms and disruptive ideas
Published in Clinical & translational oncology (01-06-2020)Get full text
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11
Transcriptional regulation of cadherins during development and carcinogenesis
Published in The International journal of developmental biology (2004)“…The cadherin superfamily of Ca(2+)-dependent homophilic adhesion molecules plays a critical role in regulating cell-to-cell interactions. During development,…”
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435 LOXL2 as a new marker of basal-like phenotype in breast cancer
Published in European journal of cancer supplements (2010)Get full text
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Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions
Published in The Journal of biological chemistry (06-06-2003)“…The Snail transcription factor has been described recently as a strong repressor of E-cadherin in epithelial cell lines, where its stable expression leads to…”
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Neutrophils instruct homeostatic and pathological states in naive tissues
Published in The Journal of experimental medicine (05-11-2018)“…Immune protection relies on the capacity of neutrophils to infiltrate challenged tissues. Naive tissues, in contrast, are believed to remain free of these…”
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The new deal a potentia role for secretec vesicles in innate immunity and tumor progression
Published in Frontiers in immunology (24-02-2015)Get full text
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Lipid‐induced lysosomal damage after demyelination corrupts microglia protective function in lysosomal storage disorders
Published in The EMBO journal (15-01-2019)“…Neuropathic lysosomal storage disorders (LSDs) present with activated pro‐inflammatory microglia. However, anti‐inflammatory treatment failed to improve…”
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Snail Mediates E-Cadherin Repression by the Recruitment of the Sin3A/Histone Deacetylase 1 (HDAC1)/HDAC2 Complex
Published in Molecular and Cellular Biology (01-01-2004)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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P-315ΔNp73 and Δ133p53 in liquid biopsy as early diagnostic markers for colorectal cancer
Published in Annals of oncology (01-07-2019)Get full text
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The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors
Published in Journal of cell science (01-02-2003)“…Transcriptional repression mechanisms have emerged as one of the crucial processes for the downregulation of E-cadherin expression during development and…”
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