Search Results - "Peikert, Tobias"

Efficacy of Remission-Induction Regimens for ANCA-Associated Vasculitis by Specks, Ulrich, Merkel, Peter A, Seo, Philip, Spiera, Robert, Langford, Carol A, Hoffman, Gary S, Kallenberg, Cees G.M, St. Clair, E. William, Fessler, Barri J, Ding, Linna, Viviano, Lisa, Tchao, Nadia K, Phippard, Deborah J, Asare, Adam L, Lim, Noha, Ikle, David, Jepson, Brett, Brunetta, Paul, Allen, Nancy B, Fervenza, Fernando C, Geetha, Duvuru, Keogh, Karina, Kissin, Eugene Y, Monach, Paul A, Peikert, Tobias, Stegeman, Coen, Ytterberg, Steven R, Mueller, Mark, Sejismundo, Lourdes P, Mieras, Kathleen, Stone, John H

“…This study of ANCA-associated vasculitis compared a single course of rituximab with conventional immunosuppression with cyclophosphamide followed by…”
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Active and latent tuberculosis infections in patients treated with immune checkpoint inhibitors in a non-endemic tuberculosis area by Stroh, Gregory R., Peikert, Tobias, Escalante, Patricio

“…Background Immune checkpoint inhibitors (ICIs) blocking inhibitory immune pathways (e.g., programmed cell death protein-1/-ligand1 [PD-1/PD-L1]) have…”
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Knowledge Gaps and Research Priorities in Immune Checkpoint Inhibitor-related Pneumonitis. An Official American Thoracic Society Research Statement by Sears, Catherine R, Peikert, Tobias, Possick, Jennifer D, Naidoo, Jarushka, Nishino, Mizuki, Patel, Sandip P, Camus, Philippe, Gaga, Mina, Garon, Edward B, Gould, Michael K, Limper, Andrew H, Montgrain, Philippe R, Travis, William D, Rivera, M Patricia

“…Immune checkpoint inhibitors (ICIs) have revolutionized cancer care but are associated with unique adverse events, including potentially life-threatening…”
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Heterogeneity of Programmed Cell Death Ligand 1 Expression in Multifocal Lung Cancer by Mansfield, Aaron S, Murphy, Stephen J, Peikert, Tobias, Yi, Eunhee S, Vasmatzis, George, Wigle, Dennis A, Aubry, Marie Christine

“…The expression of programmed cell death ligand 1 (PD-L1) provides limited predictive value in identifying patients most likely to respond to immunotherapy. As…”
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Clinical and Histopathologic Features of Immune Checkpoint Inhibitor-related Pneumonitis by Larsen, Brandon T, Chae, June M, Dixit, Anuj S, Hartman, Thomas E, Peikert, Tobias, Roden, Anja C

“…Immune checkpoint inhibitors (ICIs) have revolutionized oncology, but are associated with immune-related adverse events. Clinically, pneumonitis is a…”
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Risk assessment of latent tuberculosis infection through a multiplexed cytokine biosensor assay and machine learning feature selection by Robison, Heather M., Chapman, Cole A., Zhou, Haowen, Erskine, Courtney L., Theel, Elitza, Peikert, Tobias, Lindestam Arlehamn, Cecilia S., Sette, Alessandro, Bushell, Colleen, Welge, Michael, Zhu, Ruoqing, Bailey, Ryan C., Escalante, Patricio

“…Accurate detection and risk stratification of latent tuberculosis infection (LTBI) remains a major clinical and public health problem. We hypothesize that…”
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Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis by Stone, John H, Merkel, Peter A, Spiera, Robert, Seo, Philip, Langford, Carol A, Hoffman, Gary S, Kallenberg, Cees G.M, St. Clair, E. William, Turkiewicz, Anthony, Tchao, Nadia K, Webber, Lisa, Ding, Linna, Sejismundo, Lourdes P, Mieras, Kathleen, Weitzenkamp, David, Ikle, David, Seyfert-Margolis, Vicki, Mueller, Mark, Brunetta, Paul, Allen, Nancy B, Fervenza, Fernando C, Geetha, Duvuru, Keogh, Karina A, Kissin, Eugene Y, Monach, Paul A, Peikert, Tobias, Stegeman, Coen, Ytterberg, Steven R, Specks, Ulrich

“…This multicenter, randomized, double-blind, double-dummy, noninferiority trial compared rituximab with cyclophosphamide for remission induction in…”
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Assessment of interobserver concordance in radiomic tools for lung nodule classification, with a focus on BRODERS and SILA by Al-Ghoula, Faysal, Patel, Khushbu, Falde, Sam, Rajagopalan, Srinivasan, Bartholmai, Brian, Maldonado, Fabien, Peikert, Tobias

“…While CT lung cancer screening reduces lung cancer-specific mortality, there are remaining challenges. Radiomic tools promiss to address these challenges,…”
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The Role of Vascular Endothelial Growth Factor in the Pathogenesis, Diagnosis and Treatment of Malignant Pleural Effusion by Bradshaw, Michael, Mansfield, Aaron, Peikert, Tobias

“…Malignant pleural effusions (MPEs) are a significant source of cancer-related morbidity. Over 150,000 patients in the United States suffer from breathlessness…”
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Progress in the Management of Malignant Pleural Mesothelioma in 2017 by McCambridge, Amanda J, Napolitano, Andrea, Mansfield, Aaron S, Fennell, Dean A, Sekido, Yoshitaka, Nowak, Anna K, Reungwetwattana, Thanyanan, Mao, Weimin, Pass, Harvey I, Carbone, Michele, Yang, Haining, Peikert, Tobias

“…Malignant pleural mesothelioma (MPM) is an uncommon, almost universally fatal, asbestos-induced malignancy. New and effective strategies for diagnosis,…”
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Scientific Advances and New Frontiers in Mesothelioma Therapeutics by Mutti, Luciano, Peikert, Tobias, Robinson, Bruce W S, Scherpereel, Arnaud, Tsao, Anne S, de Perrot, Marc, Woodard, Gavitt A, Jablons, David M, Wiens, Jacinta, Hirsch, Fred R, Yang, Haining, Carbone, Michele, Thomas, Anish, Hassan, Raffit

“…Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer that arises from the mesothelial surface of the pleural and peritoneal cavities, the…”
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Identification of independent primary tumors and intrapulmonary metastases using DNA rearrangements in non-small-cell lung cancer by Murphy, Stephen J, Aubry, Marie-Christine, Harris, Faye R, Halling, Geoffrey C, Johnson, Sarah H, Terra, Simone, Drucker, Travis M, Asiedu, Michael K, Kipp, Benjamin R, Yi, Eunhee S, Peikert, Tobias, Yang, Ping, Vasmatzis, George, Wigle, Dennis A

“…Distinguishing independent primary tumors from intrapulmonary metastases in non-small-cell carcinoma remains a clinical dilemma with significant clinical…”
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Neoantigenic Potential of Complex Chromosomal Rearrangements in Mesothelioma by Mansfield, Aaron S, Peikert, Tobias, Smadbeck, James B, Udell, Julia B M, Garcia-Rivera, Enrique, Elsbernd, Laura, Erskine, Courtney L, Van Keulen, Virginia P, Kosari, Farhad, Murphy, Stephen J, Ren, Hongzheng, Serla, Vishnu V, Schaefer Klein, Janet L, Karagouga, Giannoula, Harris, Faye R, Sosa, Carlos, Johnson, Sarah H, Nevala, Wendy, Markovic, Svetomir N, Bungum, Aaron O, Edell, Eric S, Dong, Haidong, Cheville, John C, Aubry, Marie Christine, Jen, Jin, Vasmatzis, George

“…Malignant pleural mesothelioma is a disease primarily associated with exposure to the carcinogen asbestos. Whereas other carcinogen-related tumors are…”
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Novel high-resolution computed tomography-based radiomic classifier for screen-identified pulmonary nodules in the National Lung Screening Trial by Peikert, Tobias, Duan, Fenghai, Rajagopalan, Srinivasan, Karwoski, Ronald A, Clay, Ryan, Robb, Richard A, Qin, Ziling, Sicks, JoRean, Bartholmai, Brian J, Maldonado, Fabien

“…Optimization of the clinical management of screen-detected lung nodules is needed to avoid unnecessary diagnostic interventions. Herein we demonstrate the…”
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Evaluation of Computer-Aided Nodule Assessment and Risk Yield (CANARY) in Korean patients for prediction of invasiveness of ground-glass opacity nodule by Lee, Juyoung, Bartholmai, Brian, Peikert, Tobias, Chun, Jaehee, Kim, Hojin, Kim, Jin Sung, Park, Seong Yong

“…Differentiating the invasiveness of ground-glass nodules (GGN) is clinically important, and several institutions have attempted to develop their own solutions…”
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A method for identification and analysis of non-overlapping myeloid immunophenotypes in humans by Gustafson, Michael P, Lin, Yi, Maas, Mary L, Van Keulen, Virginia P, Johnston, Patrick B, Peikert, Tobias, Gastineau, Dennis A, Dietz, Allan B

“…The development of flow cytometric biomarkers in human studies and clinical trials has been slowed by inconsistent sample processing, use of cell surface…”
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Multiparameter immunoprofiling for the diagnosis and differentiation of progressive versus nonprogressive nontuberculous mycobacterial lung disease-A pilot study by Marty, Paige K, Pathakumari, Balaji, Cox, Thomas M, Van Keulen, Virginia P, Erskine, Courtney L, Shah, Maleeha, Vadiyala, Mounika, Arias-Sanchez, Pedro, Karnakoti, Snigdha, Pennington, Kelly M, Theel, Elitza S, Lindestam Arlehamn, Cecilia S, Peikert, Tobias, Escalante, Patricio

“…Clinical prediction of nontuberculous mycobacteria lung disease (NTM-LD) progression remains challenging. We aimed to evaluate antigen-specific immunoprofiling…”
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Systematic review of response rates of sarcomatoid malignant pleural mesotheliomas in clinical trials by Mansfield, Aaron S, Symanowski, James T, Peikert, Tobias

“…Highlights • We compared overall response rates by subtypes in mesothelioma. • In a systematic review of 30 trials, 21.9% of patients responded to therapy. •…”
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Catheter based treatments for fibrosing mediastinitis by Fender, Erin A., Widmer, R. Jay, Knavel Koepsel, Erica M., Welby, John P., Kern, Ryan, Peikert, Tobias, Bjarnason, Haraldur, Holmes, David R.

“…Fibrosing mediastinitis is a rare, often debilitating and potentially lethal disease characterized by an exuberant fibroinflammatory response within the…”
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Longitudinal lung cancer prediction convolutional neural network model improves the classification of indeterminate pulmonary nodules by Paez, Rafael, Kammer, Michael N., Balar, Aneri, Lakhani, Dhairya A., Knight, Michael, Rowe, Dianna, Xiao, David, Heideman, Brent E., Antic, Sanja L., Chen, Heidi, Chen, Sheau-Chiann, Peikert, Tobias, Sandler, Kim L., Landman, Bennett A., Deppen, Stephen A., Grogan, Eric L., Maldonado, Fabien

“…A deep learning model (LCP CNN) for the stratification of indeterminate pulmonary nodules (IPNs) demonstrated better discrimination than commonly used clinical…”
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