Search Results - "Peiffer, Daniel A"

High-resolution genomic profiling of chromosomal aberrations using Infinium whole-genome genotyping by Peiffer, Daniel A, Le, Jennie M, Steemers, Frank J, Chang, Weihua, Jenniges, Tony, Garcia, Francisco, Haden, Kirt, Li, Jiangzhen, Shaw, Chad A, Belmont, John, Cheung, Sau Wai, Shen, Richard M, Barker, David L, Gunderson, Kevin L

“…Array-CGH is a powerful tool for the detection of chromosomal aberrations. The introduction of high-density SNP genotyping technology to genomic profiling,…”
Get full text

Increased LIS1 expression affects human and mouse brain development by Lu, Xin-Yan, Horner, Michele, Day-Salvatore, Debra-Lynn, Sahoo, Trilochan, Withers, Marjorie A, Cheung, Sau Wai, Gunderson, Kevin L, Hunter, Jill V, Sapir, Tamar, Peiffer, Daniel A, Yanagawa, Yuchio, Reiner, Orly, Shchelochkov, Oleg A, Levy, Talia, Lupski, James R, Nezarati, Marjan M, Martinez, Salvador, Savage, Sarah K, Shinder, Vera, Harris, David J, Ann Shotts, Vern, Bi, Weimin, Amato, Stephen S, Beaudet, Arthur L, Zhang, Feng

“…James Lupski, Orly Reiner and colleagues report seven individuals with submicroscopic copy number gains in the 17p13.3 region, supported by additional studies…”
Get full text

Power to detect risk alleles using genome-wide tag SNP panels by Eberle, Michael A, Ng, Pauline C, Kuhn, Kenneth, Zhou, Lixin, Peiffer, Daniel A, Galver, Luana, Viaud-Martinez, Karine A, Lawley, Cynthia Taylor, Gunderson, Kevin L, Shen, Richard, Murray, Sarah S

“…Advances in high-throughput genotyping and the International HapMap Project have enabled association studies at the whole-genome level. We have constructed…”
Get full text

Deletion at fragile sites is a common and early event in Barrett's esophagus by Lai, Lisa A, Kostadinov, Rumen, Barrett, Michael T, Peiffer, Daniel A, Pokholok, Dimitry, Odze, Robert, Sanchez, Carissa A, Maley, Carlo C, Reid, Brian J, Gunderson, Kevin L, Rabinovitch, Peter S

“…Barrett's esophagus (BE) is a premalignant intermediate to esophageal adenocarcinoma, which develops in the context of chronic inflammation and exposure to…”
Get full text

Schnurri transcription factors from Drosophila and vertebrates can mediate Bmp signaling through a phylogenetically conserved mechanism by Yao, Li-Chin, Blitz, Ira L, Peiffer, Daniel A, Phin, Sopheap, Wang, Ying, Ogata, Souichi, Cho, Ken W Y, Arora, Kavita, Warrior, Rahul

“…Bone Morphogenetic Proteins (Bmps) are secreted growth factors that play crucial roles in animal development across the phylogenetic spectrum. Bmp signaling…”
Get full text

Phylogenetic footprinting and genome scanning identify vertebrate BMP response elements and new target genes by von Bubnoff, Andreas, Peiffer, Daniel A., Blitz, Ira L., Hayata, Tadayoshi, Ogata, Souichi, Zeng, Qiandong, Trunnell, Matthew, Cho, Ken W.Y.

“…The complex gene regulatory networks governed by growth factor signaling are still poorly understood. In order to accelerate the rate of progress in uncovering…”
Get full text

Speech delay and autism spectrum behaviors are frequently associated with duplication of the 7q11.23 Williams-Beuren syndrome region by Berg, Jonathan S, Brunetti-Pierri, Nicola, Peters, Sarika U, Kang, Sung-Hae L, Fong, Chin-to, Salamone, Jessica, Freedenberg, Debra, Hannig, Vickie L, Prock, Lisa Albers, Miller, David T, Raffalli, Peter, Harris, David J, Erickson, Robert P, Cunniff, Christopher, Clark, Gary D, Blazo, Maria A, Peiffer, Daniel A, Gunderson, Kevin L, Sahoo, Trilochan, Patel, Ankita, Lupski, James R, Beaudet, Arthur L, Cheung, Sau Wai

“…Williams-Beuren syndrome is among the most well-characterized microdeletion syndromes, caused by recurrent de novo microdeletions at 7q11.23 mediated by…”
Get full text

Genomic profiling of 766 cancer‐related genes in archived esophageal normal and carcinoma tissues by Chen, Jing, Guo, Liping, Peiffer, Daniel A., Zhou, Lixin, Chan, Owen Tsan Mo, Bibikova, Marina, Wickham‐Garcia, Eliza, Lu, Shih‐Hsin, Zhan, Qimin, Wang‐Rodriguez, Jessica, Jiang, Wei, Fan, Jian‐Bing

“…We employed the BeadArray™ technology to perform a genetic analysis in 33 formalin‐fixed, paraffin‐embedded (FFPE) human esophageal carcinomas, mostly…”
Get full text

Single nucleotide polymorphism-based genome-wide chromosome copy change, loss of heterozygosity, and aneuploidy in Barrett's esophagus neoplastic progression by Li, Xiaohong, Galipeau, Patricia C, Sanchez, Carissa A, Blount, Patricia L, Maley, Carlo C, Arnaudo, Jessica, Peiffer, Daniel A, Pokholok, Dmitry, Gunderson, Kevin L, Reid, Brian J

“…Chromosome copy gain, loss, and loss of heterozygosity (LOH) involving most chromosomes have been reported in many cancers; however, less is known about…”
Get full text

Design of tag SNP whole genome genotyping arrays by Peiffer, Daniel A, Gunderson, Kevin L

“…Whole genome association studies have recently been enabled by combining tag SNP information derived from the International HapMap project with novel whole…”
Get more information

Microarray optimizations: increasing spot accuracy and automated identification of true microarray signals by Tran, Peter H., Peiffer, Daniel A., Shin, Yongchol, Meek, Lauren M., Brody, James P., Cho, Ken W. Y.

“…In this paper, fluorescent microarray images and various analysis techniques are described to improve the microarray data acquisition processes. Signal…”
Get full text

Delineation of the proximal 3q microdeletion syndrome by Simovich, Marcia J., Bland, Steven D., Peiffer, Daniel A., Gunderson, Kevin L., Cheung, Sau Wai, Yatsenko, Svetlana A., Shinawi, Marwan

“…Interstitial deletions of the proximal long arm of chromosome 3 are very rare and a defined clinical phenotype is not established yet. We report on the…”
Get full text

Mosaic tetrasomy 12p with triplication of 12p detected by array-based comparative genomic hybridization of peripheral blood DNA by Powis, Zöe, Kang, Sung-Hae L., Cooper, M. Lance, Patel, Ankita, Peiffer, Daniel A., Hawkins, Anne, Heidenreich, Randall, Gunderson, Kevin L., Cheung, Sau W., Erickson, Robert P.

“…A patient whose dysmorphism at birth was not diagnostic for Pallister–Killian syndrome (PKS) was found to have mosaic tetrasomy 12p by an array‐based…”
Get full text

Identification of neural genes using Xenopus DNA microarrays by Shin, Yongchol, Kitayama, Atsushi, Koide, Tetsuya, Peiffer, Daniel A., Mochii, Makoto, Liao, Arnold, Ueno, Naoto, Cho, Ken W.Y.

“…To isolate novel genes regulating neural induction, we used a DNA microarray approach. As neural induction is thought to occur by means of the inhibition of…”
Get full text

A Xenopus DNA microarray approach to identify novel direct BMP target genes involved in early embryonic development by Peiffer, Daniel A., Von Bubnoff, Andreas, Shin, Yongchol, Kitayama, Atsushi, Mochii, Makoto, Ueno, Naoto, Cho, Ken W.Y.

“…Bone morphogenetic proteins (BMPs), a subgroup of the transforming growth factor‐beta (TGF‐β) superfamily, were originally isolated from bone on the basis of…”
Get full text

Mapping and sequencing of structural variation from eight human genomes by Eichler, Evan E, Kidd, Jeffrey M, Cooper, Gregory M, Donahue, William F, Hayden, Hillary S, Sampas, Nick, Graves, Tina, Hansen, Nancy, Teague, Brian, Alkan, Can, Antonacci, Francesca, Haugen, Eric, Zerr, Troy, Yamada, N. Alice, Tsang, Peter, Newman, Tera L, Tüzün, Eray, Cheng, Ze, Ebling, Heather M, Tusneem, Nadeem, David, Robert, Gillett, Will, Phelps, Karen A, Weaver, Molly, Saranga, David, Brand, Adrianne, Tao, Wei, Gustafson, Erik, McKernan, Kevin, Chen, Lin, Malig, Maika, Smith, Joshua D, Korn, Joshua M, McCarroll, Steven A, Altshuler, David A, Peiffer, Daniel A, Dorschner, Michael, Stamatoyannopoulos, John, Schwartz, David, Nickerson, Deborah A, Mullikin, James C, Wilson, Richard K, Bruhn, Laurakay, Olson, Maynard V, Kaul, Rajinder, Smith, Douglas R

“…Genetic variation among individual humans occurs on many different scales, ranging from gross alterations in the human karyotype to single nucleotide changes…”
Get full text

Increased LIS1 expression affects human and mouse brain development: Making diversity count by WEIMIN BI, SAPIR, Tamar, NEZARATI, Marjan M, SHOTTS, Vern Ann, AMATO, Stephen S, SAVAGE, Sarah K, HARRIS, David J, DAY-SALVATORE, Debra-Lynn, HORNER, Michele, LU, Xin-Yan, SAHOO, Trilochan, YANAGAWA, Yuchio, SHCHELOCHKOV, Oleg A, BEAUDET, Arthur L, SAU WAI CHEUNG, MARTINEZ, Salvador, LUPSKI, James R, REINER, Orly, FENG ZHANG, WITHERS, Marjorie A, HUNTER, Jill V, LEVY, Talia, SHINDER, Vera, PEIFFER, Daniel A, GUNDERSON, Kevin L

Get full text

SNP-based Genome-wide Chromosome Copy Change, LOH, and Aneuploidy in Barrett’s Esophagus Neoplastic Progression by Li, Xiaohong, Galipeau, Patricia C., Sanchez, Carissa A., Blount, Patricia L., Maley, Carlo C., Arnaudo, Jessica, Peiffer, Daniel A., Pokholok, Dmitry, Gunderson, Kevin L., Reid, Brian J.

Get full text

Mapping and sequencing of structural variation from eight human genomes: Making diversity count by KIDD, Jeffrey M, COOPER, Gregory M, HAUGEN, Eric, ZERR, Troy, YAMADA, N. Alice, TSANG, Peter, NEWMAN, Tera L, TÜZÜN, Eray, ZE CHENG, EBLING, Heather M, TUSNEEM, Nadeem, DAVID, Robert, DONAHUE, William F, GILLETT, Will, PHELPS, Karen A, WEAVER, Molly, SARANGA, David, BRAND, Adrianne, WEI TAO, GUSTAFSON, Erik, MCKERNAN, Kevin, LIN CHEN, MALIG, Maika, HAYDEN, Hillary S, SMITH, Joshua D, KORN, Joshua M, MCCARROLL, Steven A, ALTSHULER, David A, PEIFFER, Daniel A, DORSCHNER, Michael, STAMATOYANNOPOULOS, John, SCHWARTZ, David, NICKERSON, Deborah A, MULLIKIN, James C, SAMPAS, Nick, WILSON, Richard K, BRUHN, Laurakay, OLSON, Maynard V, KAUL, Rajinder, SMITH, Douglas R, EICHLER, Evan E, GRAVES, Tina, HANSEN, Nancy, TEAGUE, Brian, ALKAN, Can, ANTONACCI, Francesca

Get full text

Identification of neural genes usingXenopus DNA microarrays by Shin, Yongchul, Kitayama, Atsushi, Koide, Tetsuya, Peiffer, Daniel A., Mochii, Makoto, Liao, Arnold, Ueno, Naoto, Cho, Ken W.Y.

Get full text