Search Results - "Pei, Qiang"
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1
Asymmetric Deoxygenative Alkynylation of Tertiary Amides Enabled by Iridium/Copper Bimetallic Relay Catalysis
Published in Angewandte Chemie International Edition (13-12-2021)“…A variety of inert tertiary amides have been successfully transformed into synthetically important chiral propargylamines in high yields with good to excellent…”
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2
Rational Engineering of a Dynamic, Entropy‐Driven DNA Nanomachine for Intracellular MicroRNA Imaging
Published in Angewandte Chemie International Edition (24-07-2017)“…We rationally engineered an elegant entropy‐driven DNA nanomachine with three‐dimensional track and applied it for intracellular miRNAs imaging. The proposed…”
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3
Iridium‐Catalyzed Reductive Alkylations of Secondary Amides
Published in Angewandte Chemie International Edition (27-08-2018)“…Reported herein is the first direct, metal‐catalyzed reductive functionalization of secondary amides to give functionalized amines and heterocycles. The method…”
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4
Evans’ Chiral Auxiliary‐Based Asymmetric Synthetic Methodology and Its Modern Extensions
Published in European journal of organic chemistry (22-01-2024)“…Although the asymmetric catalysis has made a spurt of progress, the use of chiral auxiliaries remains crucial in asymmetric synthesis due to both the…”
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5
Enantioselective total syntheses of (+)-stemofoline and three congeners based on a biogenetic hypothesis
Published in Nature communications (20-10-2020)“…The powerful insecticidal and multi-drug-resistance-reversing activities displayed by the stemofoline group of alkaloids render them promising lead structures…”
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6
A highly integrated DNA nanomachine operating in living cells powered by an endogenous stimulus
Published in Chemical science (Cambridge) (2018)“…Synthetic molecular machines have received increasing attention because of their great ability to mimic natural biological motors and create novel modes of…”
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7
Enantioselective Reductive Cyanation and Phosphonylation of Secondary Amides by Iridium and Chiral Thiourea Sequential Catalysis
Published in Angewandte Chemie International Edition (12-04-2021)“…The combination of transition‐metal catalysis and organocatalysis increasingly offers chemists opportunities to realize diverse unprecedented chemical…”
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8
Direct Transformation of Secondary Amides into Secondary Amines: Triflic Anhydride Activated Reductive Alkylation
Published in Angewandte Chemie International Edition (13-08-2012)“…Versatile and mild: The first general method for the title transformation has been developed (see scheme; 2‐F‐Py=2‐fluoropyridine; Tf=trifluorosulfonyl). The…”
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9
Glycyrrhizin mitigates radiation‐induced acute lung injury by inhibiting the HMGB1/TLR4 signalling pathway
Published in Journal of cellular and molecular medicine (01-01-2020)“…Radiation‐induced lung injury (RILI) is the major complication of thoracic radiation therapy, and no effective treatment is available. This study explored the…”
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10
Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols
Published in Nature communications (29-01-2018)“…Enantiopure vicinal amino alcohols and derivatives are essential structural motifs in natural products and pharmaceutically active molecules, and serve as main…”
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11
Rapid Generation of Molecular Complexity by Chemical Synthesis: Highly Efficient Total Synthesis of Hexacyclic Alkaloid (−)‐Chaetominine and Its Biosynthetic Implications
Published in Chemical record (01-02-2019)“…The efficiency becomes a key issue in today's natural product total synthesis. While biomimetic synthesis is one of the most elegant strategies to achieve…”
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12
Concise Total Synthesis of (−)‐Quinocarcin Enabled by Catalytic Enantioselective Reductive 1,3‐Dipolar Cycloaddition of Secondary Amides
Published in Angewandte Chemie International Edition (19-06-2023)“…A concise asymmetric total synthesis of (−)‐quinocarcin has been accomplished with high step economy from commercially available starting materials. A…”
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13
Effect of thermal process on the key aroma components of green tea with chestnut‐like aroma
Published in Journal of the science of food and agriculture (30-01-2023)“…BACKGROUND Chestnut‐like aroma is one of the unique qualities of Chinese green tea and has become an important factor influencing consumer decisions. However,…”
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14
Catalytic enantioselective reductive alkynylation of amides enables one-pot syntheses of pyrrolidine, piperidine and indolizidine alkaloids
Published in Nature communications (06-10-2023)“…The primary objective in synthetic organic chemistry is to develop highly efficient, selective, and versatile synthetic methodologies, which are essential for…”
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15
Versatile One‐Pot Synthesis of Polysubstituted Cyclopent‐2‐enimines from α,β‐Unsaturated Amides: Imino‐Nazarov Reaction
Published in Angewandte Chemie International Edition (06-08-2018)“…The imino‐Nazarov cyclization of the polysubstituted pentan‐1,4‐diene‐3‐imines was realized. To this aim, a one‐pot procedure involving reductive…”
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16
A DNA Nanodevice-Based Platform with Diverse Capabilities
Published in Small (Weinheim an der Bergstrasse, Germany) (01-09-2023)“…Social biotic colonies often perform intricate tasks by interindividual communication and cooperation. Inspired by these biotic behaviors, a DNA nanodevice…”
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17
Ketone Synthesis by Direct, Orthogonal Chemoselective Hydroacylation of Alkenes with Amides: Use of Alkenes as Surrogates of Alkyl Carbanions
Published in Chinese journal of chemistry (01-08-2019)“…Summary of main observation and conclusion Direct functionalization of alkenes and direct transformation of carboxamides are two exciting areas that have…”
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18
Analysis of trends in testicular atrophy index values with age in patients with unilateral palpable cryptorchidism
Published in Asian journal of andrology (01-09-2022)“…Cryptorchidism affects the growth of testicular volume. Testicular volume is associated with reproductive function. The testicular atrophy index evaluates the…”
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19
Predictive Value of Eosinophil Cationic Protein in Nasal Secretions in Eosinophilic Chronic Rhinosinusitis
Published in The Laryngoscope (01-12-2023)“…To investigate the value of secretions Eosinophilic cationic protein (ECP) detection in the diagnosis of endotypes of Chronic rhinosinusitis (CRS) and its…”
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20
Two‐Step Catalytic Transformation of N‐Benzyllactams to Alkaloids (±)‐Solenopsin, (±)‐Solenopsin A, and (+)‐Julifloridine
Published in European journal of organic chemistry (09-01-2020)“…We report herein that the Ir and CuI bis‐metal catalyzed reductive alkynylation of amides, a method that we developed previously, can be extended to 6‐, 7‐,…”
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