Search Results - "Pei, Liming"

Mitochondrial Etiology of Neuropsychiatric Disorders by Pei, Liming, Wallace, Douglas C.

“…The brain has the highest mitochondrial energy demand of any organ. Therefore, subtle changes in mitochondrial energy production will preferentially affect the…”
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Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis by Chung, Ki Wung, Dhillon, Poonam, Huang, Shizheng, Sheng, Xin, Shrestha, Rojesh, Qiu, Chengxiang, Kaufman, Brett A, Park, Jihwan, Pei, Liming, Baur, Joseph, Palmer, Matthew, Susztak, Katalin

“…Fibrosis is the final common pathway leading to end-stage renal failure. By analyzing the kidneys of patients and animal models with fibrosis, we observed a…”
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Single-nucleus transcriptomic survey of cell diversity and functional maturation in postnatal mammalian hearts by Hu, Peng, Liu, Jian, Zhao, Juanjuan, Wilkins, Benjamin J, Lupino, Katherine, Wu, Hao, Pei, Liming

“…A fundamental challenge in understanding cardiac biology and disease is that the remarkable heterogeneity in cell type composition and functional states have…”
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Growth Differentiation Factor 15 Maturation Requires Proteolytic Cleavage by PCSK3, -5, and -6 by Li, Jing Jing, Liu, Jian, Lupino, Katherine, Liu, Xueyuan, Zhang, Lili, Pei, Liming

“…Growth differentiation factor 15 (GDF15) is a secreted protein with pleotropic functions from the transforming growth factor β (TGF-β) family. GDF15 is…”
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The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation by Dhillon, Poonam, Park, Jihwan, Hurtado del Pozo, Carmen, Li, Lingzhi, Doke, Tomohito, Huang, Shizheng, Zhao, Juanjuan, Kang, Hyun Mi, Shrestra, Rojesh, Balzer, Michael S., Chatterjee, Shatakshee, Prado, Patricia, Han, Seung Yub, Liu, Hongbo, Sheng, Xin, Dierickx, Pieterjan, Batmanov, Kirill, Romero, Juan P., Prósper, Felipe, Li, Mingyao, Pei, Liming, Kim, Junhyong, Montserrat, Nuria, Susztak, Katalin

“…Kidney disease is poorly understood because of the organ’s cellular diversity. We used single-cell RNA sequencing not only in resolving differences in injured…”
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Nuclear receptors: Decoding metabolic disease by Sonoda, Junichiro, Pei, Liming, Evans, Ronald M.

“…Nuclear receptors (NR) are a superfamily of ligand-activated transcription factors that regulate development, reproduction, and metabolism of lipids, drugs and…”
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GDF15 is a heart‐derived hormone that regulates body growth by Wang, Ting, Liu, Jian, McDonald, Caitlin, Lupino, Katherine, Zhai, Xiandun, Wilkins, Benjamin J, Hakonarson, Hakon, Pei, Liming

“…The endocrine system is crucial for maintaining whole‐body homeostasis. Little is known regarding endocrine hormones secreted by the heart other than…”
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Regulation of Macrophage Inflammatory Gene Expression by the Orphan Nuclear Receptor Nur77 by Pei, Liming, Castrillo, Antonio, Tontonoz, Peter

“…Members of the nuclear hormone receptor superfamily have emerged as important regulators of macrophage gene expression in inflammation and disease. Previous…”
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NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism by Tontonoz, Peter, Pei, Liming, Waki, Hironori, Vaitheesvaran, Bhavapriya, Wilpitz, Damien C, Kurland, Irwin J

“…Hepatic glucose production is crucial for glucose homeostasis, and its dysregulation contributes to the pathogenesis of diabetes. Here, we show that members of…”
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Induction of NR4A Orphan Nuclear Receptor Expression in Macrophages in Response to Inflammatory Stimuli by Pei, Liming, Castrillo, Antonio, Chen, Mingyi, Hoffmann, Alexander, Tontonoz, Peter

“…Oxidized lipids and inflammatory cytokines are believed to play a causal role in atherosclerosis through the regulation of gene expression in macrophages and…”
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Nur77 Coordinately Regulates Expression of Genes Linked to Glucose Metabolism in Skeletal Muscle by Chao, Lily C, Zhang, Zidong, Pei, Liming, Saito, Tsugumichi, Tontonoz, Peter, Pilch, Paul F

“…Innervation is important for normal metabolism in skeletal muscle, including insulin-sensitive glucose uptake. However, the transcription factors that…”
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Insulin Resistance and Altered Systemic Glucose Metabolism in Mice Lacking Nur77 by Chao, Lily C, Wroblewski, Kevin, Zhang, Zidong, Pei, Liming, Vergnes, Laurent, Ilkayeva, Olga R, Ding, Shi Ying, Reue, Karen, Watt, Matthew J, Newgard, Christopher B, Pilch, Paul F, Hevener, Andrea L, Tontonoz, Peter

“…Insulin Resistance and Altered Systemic Glucose Metabolism in Mice Lacking Nur77 Lily C. Chao 1 , Kevin Wroblewski 1 , Zidong Zhang 2 , Liming Pei 1 , Laurent…”
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Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice[S] by Chao, Lily C., Soto, Erin, Hong, Cynthia, Ito, Ayaka, Pei, Liming, Chawla, Ajay, Conneely, Orla M., Tangirala, Rajendra K., Evans, Ronald M., Tontonoz, Peter

“…The formation of the atherosclerotic lesion is a complex process influenced by an array of inflammatory and lipid metabolism pathways. We previously…”
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Impaired Development of Atherosclerosis in Hyperlipidemic Ldlr−/− and ApoE−/− Mice Transplanted With Abcg1−/− Bone Marrow by Baldán, Ángel, Pei, Liming, Lee, Richard, Tarr, Paul, Tangirala, Rajendra K, Weinstein, Michael M, Frank, Joy, Li, Andrew C, Tontonoz, Peter, Edwards, Peter A

“…OBJECTIVE—The lungs of Abcg1 mice accumulate macrophage foam cells that contain high levels of unesterified and esterified cholesterol, consistent with a role…”
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Synthetic LXR Ligand Inhibits the Development of Atherosclerosis in Mice by Joseph, Sean B., McKilligin, Elaine, Pei, Liming, Watson, Michael A., Collins, Alan R., Laffitte, Bryan A., Chen, Mingyi, Noh, Grace, Goodman, Joanne, Hagger, Graham N., Tran, Jonathan, Tippin, Tim K., Wang, Xuping, Lusis, Aldons J., Hsueh, Willa A., Law, Ronald E., Collins, Jon L., Willson, Timothy M., Tontonoz, Peter

“…The nuclear receptors LXRα and LXRβ have been implicated in the control of cholesterol and fatty acid metabolism in multiple cell types. Activation of these…”
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SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis by Nofsinger, Russell R, Li, Pingping, Hong, Suk-Hyun, Jonker, Johan W, Barish, Grant D, Ying, Hao, Cheng, Sheue-yann, LeBlanc, Mathias, Xu, Wei, Pei, Liming, Kang, Yeon-Joo, Nelson, Michael, Downes, Michael, Yu, Ruth T, Olefsky, Jerrold M, Lee, Chih-Hao, Evans, Ronald M

“…The nuclear receptor corepressor, silencing mediator of retinoid and thyroid hormone receptors (SMRT), is recruited by a plethora of transcription factors to…”
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Autoregulation of the Human Liver X Receptor α Promoter by Laffitte, Bryan A., Joseph, Sean B., Walczak, Robert, Pei, Liming, Wilpitz, Damien C., Collins, Jon L., Tontonoz, Peter

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papilla by BERRY, Rachel, HAREWOOD, Louise, DAVIES, Jamie A, EVANS, Ronald M, FITZPATRICK, David R, LIMING PEI, FISHER, Malcolm, BROWNSTEIN, David, ROSS, Allyson, ALAYNICK, William A, MOSS, Julie, HASTIE, Nicholas D, HOHENSTEIN, Peter

“…Congenital anomalies of the kidney and urinary tract (CAKUTs) are common disorders of human development affecting the renal parechyma, renal pelvis, ureter,…”
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Abstract 371: Cardiac Endocrinology: Biology of a Heart-derived Hormone That Regulates Body Growth by Pei, Liming

“…Abstract only The endocrine system is crucial for maintaining whole-body homeostasis. Little is known regarding endocrine hormones secreted by the heart other…”
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Transcription of the Vascular Endothelial Growth Factor Gene in Macrophages Is Regulated by Liver X Receptors by Walczak, Robert, Joseph, Sean B., Laffitte, Bryan A., Castrillo, Antonio, Pei, Liming, Tontonoz, Peter

“…Macrophages are an important source of angiogenic activity in wound healing, cancer, and chronic inflammation. Vascular endothelial growth factor (VEGF), a…”
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