Search Results - "Pei, Jianqiu"
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1
Transplantation of murine neonatal cardiac macrophage improves adult cardiac repair
Published in Cellular & molecular immunology (01-02-2021)Get full text
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Loss of Phosphatase and Tensin Homolog Promotes Cardiomyocyte Proliferation and Cardiac Repair After Myocardial Infarction
Published in Circulation (New York, N.Y.) (01-12-2020)Get full text
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LncRNA LncHrt preserves cardiac metabolic homeostasis and heart function by modulating the LKB1-AMPK signaling pathway
Published in Basic research in cardiology (01-12-2021)“…Metabolic modulation is a promising therapeutic approach to prevent adverse remodeling of the ischemic heart. Because little is known about the involvement of…”
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4
Models for calcific aortic valve disease in vivo and in vitro
Published in Cell regeneration (01-03-2024)“…Calcific Aortic Valve Disease (CAVD) is prevalent among the elderly as the most common valvular heart disease. Currently, no pharmaceutical interventions can…”
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Long noncoding RNA Cfast regulates cardiac fibrosis
Published in Molecular therapy. Nucleic acids (05-03-2021)“…Cardiac fibrosis occurs in most cardiac diseases, which reduces cardiac muscle compliance, impairs both systolic and diastolic heart function and, ultimately,…”
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Lysophosphatidic Acid Receptor 3 Suppress Neutrophil Extracellular Traps Production and Thrombosis During Sepsis
Published in Frontiers in immunology (07-04-2022)“…Sepsis consists of life-threatening organ dysfunction resulting from a dysregulated response to infection. Recent studies have found that excessive neutrophil…”
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LPA3-mediated lysophosphatidic acid signaling promotes postnatal heart regeneration in mice
Published in Theranostics (01-01-2020)“…Background: Lysophosphatidic acid (LPA) is a small glycerophospholipid that acts as a potent extracellular signal in various biological processes and diseases…”
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A Novel LncRNA SNHG3 Promotes Osteoblast Differentiation Through BMP2 Upregulation in Aortic Valve Calcification
Published in JACC. Basic to translational science (01-09-2022)“…• The long noncoding RNA SNHG3 was upregulated in the leaflets of both patients and mice with calcific aortic valve disease. • SNHG3 can associate with EZH2 in…”
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Abstract We035: PTMA-MBD3 axis is a core heart regenerative driver in mammals
Published in Circulation research (02-08-2024)“…Abstract only Introduction: The adult mammalian heart has an extremely limited ability for regeneration after injury, whereas the fetal heart can steadily…”
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LPA2 Contributes to Vascular Endothelium Homeostasis and Cardiac Remodeling After Myocardial Infarction
Published in Circulation research (19-08-2022)“…RATIONALEMyocardial infarction (MI) is one of the most dangerous adverse cardiovascular events. Our previous study found that lysophosphatidic acid (LPA) is…”
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PROTECTIVE EFFECT OF LPA2 ON VASCULAR ENDOTHELIUM HOMEOSTASIS AND CARDIAC REMODELING AFTER MYOCARDIAL INFARCTION
Published in Journal of the American College of Cardiology (24-03-2020)Get full text
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A long noncoding RNA NR_045363 controls cardiomyocyte proliferation and cardiac repair
Published in Journal of molecular and cellular cardiology (01-02-2019)“…Long noncoding RNAs (lncRNAs) play important roles in the regulation of genes involved in cell proliferation. We have previously sought to more globally…”
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13
PDGFR-β Signaling Regulates Cardiomyocyte Proliferation and Myocardial Regeneration
Published in Cell reports (Cambridge) (23-07-2019)“…Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types. The role of PDGFR signaling…”
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14
Lysophosphatidic acid promotes thrombus stability by inducing rapid formation of neutrophil extracellular traps: A new mechanism of thrombosis
Published in Journal of thrombosis and haemostasis (01-08-2020)“…Background Lysophosphatidic acid (LPA), a bioactive phospholipid released by activated platelets, can induce platelet shape changes and aggregation, which may…”
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Hydrogen Sulfide Promotes Cardiomyocyte Proliferation and Heart Regeneration via ROS Scavenging
Published in Oxidative medicine and cellular longevity (2020)“…Neonatal mouse hearts can regenerate completely in 21 days after cardiac injury, providing an ideal model to exploring heart regenerative therapeutic targets…”
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LPA 2 Contributes to Vascular Endothelium Homeostasis and Cardiac Remodeling After Myocardial Infarction
Published in Circulation research (19-08-2022)“…Myocardial infarction (MI) is one of the most dangerous adverse cardiovascular events. Our previous study found that lysophosphatidic acid (LPA) is increased…”
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PO-01-181 LEFT BUNDLE BRANCH AREA PACING WITH OR WITHOUT CONDUCTION SYSTEM CAPTURE IN HEART FAILURE MODELS
Published in Heart rhythm (01-05-2024)Get full text
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Alleviates Septic Acute Lung Injury via Protective Endothelial Barrier Function Through Activation of PLC-PKC-FAK
Published in Journal of inflammation research (30-11-2023)“…Background: Increased endothelial permeability of pulmonary vessels is a primary pathological characteristic of septic acute lung injury (ALI). Previously,…”
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Transplantation of Neonatal Mouse Cardiac Macrophages into Adult Mice
Published in Journal of visualized experiments (20-03-2021)“…In an injured neonatal myocardium, macrophages facilitate cardiomyocyte proliferation and angiogenesis and promote heart regeneration. The present study…”
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Presence and impact of anemia in patients supported with left ventricular assist devices
Published in The Journal of heart and lung transplantation (01-09-2023)“…Data on anemia and its effects on patients supported with continuous-flow left ventricular assist devices (LVADs) are lacking. This study sought to describe…”
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