Search Results - "Pei, Heying"

Therapeutic efficacy of an injectable formulation of purinostat mesylate in SU-DHL-6 tumour model by Zhu, Zejiang, Wen, Jiaolin, Xu, Yaohui, Pei, Heying, Li, Dan, Tang, Minghai, Bai, Peng, He, Jun, Yang, Zhuang, Chen, Lijuan

“…Background: Previous studies have proven that Purinostat Mesylate (PM) is a new HDAC inhibitor and exhibits significant antitumor efficacy. However, the…”
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Discovery of a highly selective JAK3 inhibitor for the treatment of rheumatoid arthritis by Pei, Heying, He, Linhong, Shao, Mingfeng, Yang, Zhuang, Ran, Yan, Li, Dan, Zhou, Yuanyuan, Tang, Minghai, Wang, Taijin, Gong, Yanqiu, Chen, Xiaoxin, Yang, Shengyong, Xiang, Mingli, Chen, Lijuan

“…Janus tyrosine kinase 3 (JAK3) is expressed in lymphoid cells and is involved in the signalling of T cell functions. The development of a selective JAK3…”
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Studies on the anti-psoriasis effects and its mechanism of a dual JAK2/FLT3 inhibitor flonoltinib maleate by Zhu, Jiali, Yang, Tao, Tang, Minghai, Yang, Zhuang, Pei, Heying, Ye, Haoyu, Tang, Yu, Cheng, Zhixuan, Lin, Ping, Chen, Lijuan

“…Psoriasis is a chronic, inflammatory autoimmune disease mediated by T cells, and characterized with abnormal proliferation and differentiation of…”
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SKLB-23bb, A HDAC6-Selective Inhibitor, Exhibits Superior and Broad-Spectrum Antitumor Activity via Additionally Targeting Microtubules by Wang, Fang, Zheng, Li, Yi, Yuyao, Yang, Zhuang, Qiu, Qiang, Wang, Xiaoyan, Yan, Wei, Bai, Peng, Yang, Jianhong, Li, Dan, Pei, Heying, Niu, Ting, Ye, Haoyu, Nie, Chunlai, Hu, Yiguo, Yang, Shengyong, Wei, Yuquan, Chen, Lijuan

“…Our previous study reported that SKLB-23bb, an orally bioavailable HDAC6-selective inhibitor, exhibited superior antitumor efficiency both and in comparison…”
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Barbigerone reverses multidrug resistance in breast MCF‐7/ADR cells by Li, Xiuxia, Wan, Li, Wang, Fang, Pei, Heying, Zheng, Li, Wu, Wenshuang, Ye, Haoyu, Wang, Yanping, Chen, Lijuan

“…Development of agents to overcome multidrug resistance (MDR) is one of the important strategies in cancer chemotherapy, and P‐glycoprotein (P‐gp) correlates…”
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SKLB023 protects mice against acute liver injury by inhibiting proinflammatory cytokine production in both T cells and macrophages by Yu, Jia, Liu, Lili, Zhang, Huiming, Wu, Yating, Pei, Heying, Ma, Liang, Xiong, Anwen, Xie, Caifeng

“…Acute liver failure is a severe clinical syndrome accompanied with excessive inflammatory response. Our previous study demonstrated that SKLB023, a novel…”
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Honokiol Ameliorates Post-Myocardial Infarction Heart Failure Through Ucp3-Mediated Reactive Oxygen Species Inhibition by Liu, Jianyu, Tang, Minghai, Li, Tao, Su, Zhengying, Zhu, Zejiang, Dou, Caixia, Liu, Yan, Pei, Heying, Yang, Jianhong, Ye, Haoyu, Chen, Lijuan

“…Post-myocardial infarction heart failure (post-MI HF) is one of the leading global causes of death, and current prevention and treatment methods still cannot…”
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Anti-psoriatic effects of Honokiol through the inhibition of NF-κB and VEGFR-2 in animal model of K14-VEGF transgenic mouse by Wen, Jiaolin, Wang, Xianhuo, Pei, Heying, Xie, Caifeng, Qiu, Neng, Li, Shucai, Wang, Wenwen, Cheng, Xia, Chen, Lijuan

“…Honokiol (HK), a biphenolic neolignan isolated from Magnolia officinalis, has been reported to possess anti-inflammatory and anti-angiogenic activaties. In…”
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Corrigendum: Honokiol ameliorates post-myocardial infarction heart failure through Ucp3-mediated reactive oxygen species inhibition by Liu, Jianyu, Tang, Minghai, Li, Tao, Su, Zhengying, Zhu, Zejiang, Dou, Caixia, Liu, Yan, Pei, Heying, Yang, Jianhong, Ye, Haoyu, Chen, Lijuan

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Author Correction: Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells by Yang, Jianhong, Zhou, Yongzhao, Cheng, Xia, Fan, Yi, He, Shichao, Li, Shucai, Ye, Haoyu, Xie, Caifeng, Wu, Wenshuang, Li, Chunyan, Pei, Heying, Li, Luyuan, Wei, Zhe, Peng, Aihua, Wei, Yuquan, Li, Weimin, Chen, Lijuan

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Correction: Therapeutic potential of a synthetic FABP4 inhibitor 8g on atherosclerosis in ApoE-deficient mice: the inhibition of lipid accumulation and inflammation by Pei, Heying, Xie, Caifeng, Liu, Yibin, Shao, Mingfeng, Chen, Jinying, Li, Dan, Ma, Liang, Chen, Lijuan

“…Correction for 'Therapeutic potential of a synthetic FABP4 inhibitor 8g on atherosclerosis in ApoE-deficient mice: the inhibition of lipid accumulation and…”
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SKLB023 blocks joint inflammation and cartilage destruction in arthritis models via suppression of nuclear factor-kappa B activation in macrophage by Xie, Caifeng, Ma, Liang, Liu, Juan, Li, Xiuxia, Pei, Heying, Xiang, Mingli, Chen, Lijuan

“…Rheumatoid arthritis (RA) is the most common arthritis and is mainly characterized by symmetric polyarticular joint disorders. Our previous study demonstrated…”
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Gambogic acid exhibits anti-psoriatic efficacy through inhibition of angiogenesis and inflammation by Wen, Jiaolin, Pei, Heying, Wang, Xianhuo, Xie, Caifeng, Li, Shucai, Huang, Li, Qiu, Neng, Wang, Wenwen, Cheng, Xia, Chen, Lijuan

“…Summary Background Psoriasis is a chronic T cell-mediated inflammatory skin disease. Studies have shown that angiogenesis plays an important role in the…”
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Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells by Yang, Jianhong, Zhou, Yongzhao, Cheng, Xia, Fan, Yi, He, Shichao, Li, Shucai, Ye, Haoyu, Xie, Caifeng, Wu, Wenshuang, Li, Chunyan, Pei, Heying, Li, Luyuan, Wei, Zhe, Peng, Aihua, Wei, Yuquan, Li, Weimin, Chen, Lijuan

“…To overcome drug resistance caused by apoptosis deficiency in patients with non-small cell lung carcinoma (NSCLC), there is a need to identify other means of…”
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Non-toxic dose of liposomal honokiol suppresses metastasis of hepatocellular carcinoma through destabilizing EGFR and inhibiting the downstream pathways by Yang, Jianhong, Pei, Heying, Luo, Hong, Fu, Afu, Yang, Hansuo, Hu, Jia, Zhao, Chengjian, Chai, LuLu, Chen, Xiang, Shao, Ximing, Wang, Chunyu, Wu, Wenshuang, Wan, Li, Ye, Haoyu, Qiu, Qiang, Peng, Aihua, Wei, Yuquan, Yang, Li, Chen, Lijuan

“…At present, there is no specific anti-metastasis drug in HCC treatment. Drugs used for primary HCC tumors and tumor metastasis are very similar, among which…”
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Synthesis and biological evaluation of novel urea- and guanidine-based derivatives for the treatment of obesity-related hepatic steatosis by Liang, Xiaolin, Pei, Heying, Ma, Liang, Ran, Yan, Chen, Jinying, Wang, Guangcheng, Chen, Lijuan

“…Leptin, the product of the obese gene, is an adipocyte-secreted protein hormone playing a key role in the progression of obesity and hepatic steatosis. In this…”
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Pharmacological effects of the water fraction of key components in the traditional Chinese prescription Mai Tong Fang on 3T3-L1 adipocytes and ob/ob diabetic mice by Ma, Liang, Huang, Li, Pei, Heying, Liu, Zhuowei, Xie, Caifeng, Lei, Lei, Chen, Xiaoxin, Ye, Haoyu, Peng, Aihua, Chen, Lijuan

“…Mai Tong Fang (MTF), a Chinese herbal combination, has been used for the treatment of diabetic nephropathy in traditional medical clinics in China. However,…”
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Truncated bFGF-mediated cationic liposomal paclitaxel for tumor-targeted drug delivery: improved pharmacokinetics and biodistribution in tumor-bearing mice by Wang, Xianhuo, Deng, Linyu, Chen, Xiang, Pei, Heying, Cai, Lulu, Zhao, Xia, Wei, Yuquan, Chen, Lijuan

“…Fibroblast growth factor receptors, overexpressed on the surface of a variety of tumor cells and on tumor neovasculature, are potential targets for tumor- and…”
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Millepachine, a novel chalcone, induces G 2 /M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo by Wu, Wenshuang, Ye, Haoyu, Wan, Li, Han, Xiaolei, Wang, Guangcheng, Hu, Jia, Tang, Minhai, Duan, Xingmei, Fan, Yi, He, Shichao, Huang, Li, Pei, Heying, Wang, Xuewei, Li, Xiuxia, Xie, Caifeng, Zhang, Ronghong, Yuan, Zhu, Mao, Yongqiu, Wei, Yuquan, Chen, Lijuan

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Ethanol extract of Piper wallichii ameliorates DSS-induced ulcerative colitis in mice: Involvement of TLR4/NF-κB/COX-2 signaling pathway by Zhao, Jiajia, Wu, Rui, Wei, Panhong, Ma, Ziyan, Pei, Heying, Hu, Jingwen, Wen, Feiyan, Wan, Li

“…Piper wallichii (family: Piperaceae), a folk herbal medicine with anti-inflammatory and anti-thrombotic properties, has been traditionally used to treat…”
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