Search Results - "Peh, CA"

Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis by Walsh, Michael, Merkel, Peter A, Peh, Chen-Au, Szpirt, Wladimir M, Puéchal, Xavier, Fujimoto, Shouichi, Hawley, Carmel M, Khalidi, Nader, Floßmann, Oliver, Wald, Ron, Girard, Louis P, Levin, Adeera, Gregorini, Gina, Harper, Lorraine, Clark, William F, Pagnoux, Christian, Specks, Ulrich, Smyth, Lucy, Tesar, Vladimir, Ito-Ihara, Toshiko, de Zoysa, Janak Rashme, Szczeklik, Wojciech, Flores-Suárez, Luis Felipe, Carette, Simon, Guillevin, Loïc, Pusey, Charles D, Casian, Alina L, Brezina, Biljana, Mazzetti, Andrea, McAlear, Carol A, Broadhurst, Elizabeth, Reidlinger, Donna, Mehta, Samir, Ives, Natalie, Jayne, David R.W

“…Among patients with severe antineutrophil cytoplasmic antibody–associated vasculitis, plasma exchange did not reduce the incidence of death or end-stage kidney…”
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Rituximab as therapy to induce remission after relapse in ANCA-associated vasculitis by Smith, Rona M, Jones, Rachel Bronwen, Specks, Ulrich, Bond, Simon, Nodale, Marianna, Aljayyousi, Reem, Andrews, Jacqueline, Bruchfeld, Annette, Camilleri, Brian, Carette, Simon, Cheung, Chee Kay, Derebail, Vimal, Doulton, Tim, Forbess, Lindsy, Fujimoto, Shouichi, Furuta, Shunsuke, Gewurz-Singer, Ora, Harper, Lorraine, Ito-Ihara, Toshiko, Khalidi, Nader, Klocke, Rainer, Koening, Curry, Komagata, Yoshinori, Langford, Carol, Lanyon, Peter, Luqmani, Raashid Ahmed, Makino, Hirofumi, McAlear, Carole A, Monach, Paul, Moreland, Larry W, Mynard, Kim, Nachman, Patrick, Pagnoux, Christian, Pearce, Fiona, Peh, Chen Au, Pusey, Charles, Ranganathan, Dwarakanathan, Rhee, Rennie L, Spiera, Robert, Sreih, Antoine G, Tesar, Vladimir, Walters, Giles, Weisman, Michael H, Wroe, Caroline, Merkel, Peter A, Jayne, David

“…Evaluation of rituximab and glucocorticoids as therapy to induce remission after relapse in ANCA-associated vasculitis (AAV) in a prospective observational…”
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Rituximab versus azathioprine for maintenance of remission for patients with ANCA-associated vasculitis and relapsing disease: an international randomised controlled trial by Smith, Rona M, Jones, Rachel B, Specks, Ulrich, Bond, Simon, Nodale, Marianna, Al-Jayyousi, Reem, Andrews, Jacqueline, Bruchfeld, Annette, Camilleri, Brian, Carette, Simon, Cheung, Chee Kay, Derebail, Vimal, Doulton, Tim, Ferraro, Alastair, Forbess, Lindsy, Fujimoto, Shouichi, Furuta, Shunsuke, Gewurz-Singer, Ora, Harper, Lorraine, Ito-Ihara, Toshiko, Khalidi, Nader, Klocke, Rainer, Koening, Curry, Komagata, Yoshinori, Langford, Carol, Lanyon, Peter, Luqmani, Raashid, McAlear, Carol, Moreland, Larry W, Mynard, Kim, Nachman, Patrick, Pagnoux, Christian, Peh, Chen Au, Pusey, Charles, Ranganathan, Dwarakanathan, Rhee, Rennie L, Spiera, Robert, Sreih, Antoine G, Tesar, Vladamir, Walters, Giles, Wroe, Caroline, Jayne, David, Merkel, Peter A

“…Following induction of remission with rituximab in anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) relapse rates are high, especially in…”
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Plasma Exchange for Renal Vasculitis and Idiopathic Rapidly Progressive Glomerulonephritis: A Meta-analysis by Walsh, Michael, MD, MSc, Catapano, Fausta, MD, PhD, Szpirt, Wladimir, MD, Thorlund, Kristian, MSc, Bruchfeld, Annette, MD, PhD, Guillevin, Loic, MD, Haubitz, Marion, MD, Merkel, Peter A., MD, MPH, Peh, Chen Au, MD, PhD, Pusey, Charles, DSc, Jayne, David, MD

“…Background Plasma exchange may be effective adjunctive treatment for renal vasculitis. We performed a systematic review and meta-analysis of randomized…”
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IgM ANCA in healthy individuals and in patients with ANCA-associated vasculitis by Jeffs, LS, Peh, CA, Nelson, A, Tan, PG, Davey, E, Chappell, K, Perkins, GB, Hurtado, PR

“…Low levels of IgM auto-antibodies have been reported in health and disease. IgM anti-neutrophil cytoplasmic antibodies (ANCA) have been reported in patients…”
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Optimization of the MHC Class I Peptide Cargo Is Dependent on Tapasin by Williams, Anthony P, Peh, Chen Au, Purcell, Anthony W, McCluskey, James, Elliott, Tim

“…The loading of MHC class I molecules with their peptide cargo is undertaken by a multimolecular peptide loading complex within the endoplasmic reticulum. We…”
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Lymphoblastoid cells express HLA‐B27 homodimers both intracellularly and at the cell surface following endosomal recycling by Bird, Lucy A., Peh, Chen Au, Kollnberger, Simon, Elliott, Tim, McMichael, Andrew J., Bowness, Paul

“…The MHC class I allele HLA‐B27 is very strongly associated with development of autoimmune spondyloarthritis, although the disease mechanism remains unknown…”
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HLA-B27–Restricted Antigen Presentation in the Absence of Tapasin Reveals Polymorphism in Mechanisms of HLA Class I Peptide Loading by Peh, Chen Au, Burrows, Scott R, Barnden, Megan, Khanna, Rajiv, Cresswell, Peter, Moss, Denis J, McCluskey, James

“…Tapasin is a resident ER protein believed to be critical for antigen presentation by HLA class I molecules. We demonstrate that allelic variation in MHC class…”
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GENETIC EVIDENCE OF EOSINOPHIL NUMBER UNDERPINNING PR3-AAV AND PLAUSIBLE HOST GENETIC PREDISPOSITION TO MICROBIAL DRIVERS OF DISEASE by Wong, L, Mescia, F, Alberici, F, Ball, MJ, Baslund, B, Brenchley, P, Bruchfeld, A, Cid, MC, Tervaert, JWC, Coulson, RMR, Farahi, N, Feighery, C, Gross, WL, Guillevin, L, Gunnarsson, I, Harper, L, Holle, JU, Hruskova, Z, Jayne, DRW, Lamprecht, P, Leslie, S, Little, MA, Martorana, D, Neumann, T, Ohlsson, S, Peh, CA, Pusey, CD, Quickert, S, Ramirez, GA, Rees, AJ, Rewerska, B, Salama, AD, Sanders, JSF, Savage, CO, Segelmark, M, Solans, R, Stegeman, CA, Szczeklik, W, Terrier, B, Tesar, V, Watts, RA, Wieczorek, S, Wilde, B, Zwerina, J, Vaglio, A, Lyons, PA, Smith, KGC

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Quantitative and Qualitative Influences of Tapasin on the Class I Peptide Repertoire by Purcell, Anthony W, Gorman, Jeffrey J, Garcia-Peydro, Marina, Paradela, Alberto, Burrows, Scott R, Talbo, Gert H, Laham, Nihay, Peh, Chen Au, Reynolds, Eric C, Lopez de Castro, Jose A, McCluskey, James

“…Tapasin is critical for efficient loading and surface expression of most HLA class I molecules. The high level surface expression of HLA-B*2705 on…”
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BK transplant nephropathy successfully treated with cidofovir by Keller, Lisa S., Peh, Chen Au, Nolan, James, Bannister, Kym M., Clarkson, Anthony R., Faull, Randall J.

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Rituximab use in systemic lupus erythematosus pneumonitis and a review of current reports by Lim, S. W., Gillis, D., Smith, W., Hissaria, P., Greville, H., Peh, C. A.

“…Rituximab is a chimeric monoclonal antibody specific for human CD20 that causes selective transient depletion of the CD20+ B‐cell subpopulation. We report the…”
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Distinct Functions of Tapasin Revealed by Polymorphism in MHC Class I Peptide Loading by Peh, Chen Au, Laham, Nihay, Burrows, Scott R, Zhu, Yong, McCluskey, James

“…Peptide assembly with class I molecules is orchestrated by multiple chaperones including tapasin, which bridges class I molecules with the TAP and is critical…”
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BRIEF COMMUNICATION: Rituximab use in systemic lupus erythematosus pneumonitis and a review of current reports by Lim, S W, Gillis, D, Smith, W, Hissaria, P, Greville, H, Peh, CA

“…Rituximab is a chimeric monoclonal antibody specific for human CD20 that causes selective transient depletion of the CD20 super(+) B-cell subpopulation. We…”
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Crystalloid deposits in the kidney by KELLER, LISA SUZANNE, FAULL, RANDALL JAMES, SMITH, PETER, SWIFT, JEFFREY, BANNISTER, KYM MALCOLM, OTTO, SOPHIE, PEH, CHEN AU

“…Light chain‐producing lymphoproliferative disorders such as multiple myeloma are frequently complicated by renal impairment. Typically, the renal biopsy of a…”
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Recurrent mesangial IgA nephritis following renal transplantation by Odum, J, Peh, C A, Clarkson, A R, Bannister, K M, Seymour, A E, Gillis, D, Thomas, A C, Mathew, T H, Woodroffe, A J

“…Recurrence of mesangial IgA deposits in renal allografts of patients whose original disease was primary IgA nephropathy (IgAN) has been studied. Forty-six…”
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Endogenous and exogenous factors contributing to the surface expression of HLA B27 on mutant APC by Purcell, Anthony W., Kelly, Alexandra J., Peh, Chen Au, Dudek, Nadine L., McCluskey, James

“…We have examined the expression of HLA B∗2705 in the mutant cell line 721.220, which lacks endogenous HLA A and B alleles and expresses a defective tapasin…”
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Human leukocyte antigen phenotype imposes complex constraints on the antigen-specific cytotoxic T lymphocyte repertoire by Burrows, S R, Silins, S L, Cross, S M, Peh, C A, Rischmueller, M, Burrows, J M, Elliott, S L, McCluskey, J

“…The memory response to the immunodominant Epstein-Barr virus (EBV) epitope FLRGRAYGL, which associates with HLA B8, is exceptionally restricted, being…”
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The cell biology of MHC class I antigen presentation by Williams, A., Peh, C. A., Elliott, T.

“…: MHC class I antigen presentation refers to the co‐ordinated activities of many intracellular pathways that promote the cell surface appearance of MHC class…”
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Treatment of IgA nephropathy by Peh, C A, Clarkson, A R

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