Search Results - "Peeters, Hanneke J. M."

EGFRvIII expression triggers a metabolic dependency and therapeutic vulnerability sensitive to autophagy inhibition by Jutten, Barry, Keulers, Tom G., Peeters, Hanneke J. M., Schaaf, Marco B. E., Savelkouls, Kim G. M., Compter, Inge, Clarijs, Ruud, Schijns, Olaf E. M. G., Ackermans, Linda, Teernstra, Onno P. M., Zonneveld, Marijke I., Colaris, Resi M. E., Dubois, Ludwig, Vooijs, Marc A., Bussink, Johan, Sotelo, Julio, Theys, Jan, Lammering, Guido, Rouschop, Kasper M. A.

“…Expression of EGFRvIII is frequently observed in glioblastoma and is associated with increased cellular proliferation, enhanced tolerance to metabolic…”
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GABARAPL1 is required for increased EGFR membrane expression during hypoxia by Keulers, Tom G, Schaaf, Marco B.E, Peeters, Hanneke J.M, Savelkouls, Kim G.M, Vooijs, Marc A, Bussink, Johan, Jutten, Barry, Rouschop, Kasper M.A

“…Abstract Background and purpose The epidermal growth factor receptor (EGFR) is overexpressed, amplified or mutated in various human epithelial tumors and…”
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Canonical autophagy does not contribute to cellular radioresistance by Schaaf, Marco B.E, Jutten, Barry, Keulers, Tom G, Savelkouls, Kim G.M, Peeters, Hanneke J.M, van den Beucken, Twan, van Schooten, Frederik-Jan, Godschalk, Roger W, Vooijs, Marc, Rouschop, Kasper M.A

“…Abstract Background (Pre)clinical studies indicate that autophagy inhibition increases response to anti-cancer therapies. Although promising, due to…”
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