Search Results - "Peers, S."

Chitosan hydrogels for sustained drug delivery by Peers, S., Montembault, A., Ladavière, C.

“…Sustainable and controlled delivery of drugs is at the centre of a huge amount of undertaken researches. The ability of hydrogels, high water content…”
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Chitosan hydrogels incorporating colloids for sustained drug delivery by Peers, S., Montembault, A., Ladavière, C.

“…In today's biomedical research, a huge effort is being made towards the development of efficient drug delivery systems, achieving sustainable and controlled…”
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Embedment of liposomes into chitosan physical hydrogel for the delayed release of antibiotics or anaesthetics, and its first ESEM characterization by Peers, S., Alcouffe, P., Montembault, A., Ladavière, C.

“…[Display omitted] •An original liposomes/chitosan hydrogel assembly was prepared by using a reproducible process.•An antibiotic (rifampicin) or an anaesthetic…”
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Effects of hypoxia and oxidative stress on expression of neprilysin in human neuroblastoma cells and rat cortical neurones and astrocytes by Fisk, Lilia, Nalivaeva, Natalia N, Boyle, John P, Peers, Christopher S, Turner, Anthony J

“…Pathogenesis of Alzheimer's disease (AD), which is characterised by accumulation of extracellular deposits of beta-amyloid peptide (Abeta) in the brain, has…”
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Proteomic biomarkers for acute interstitial lung disease in gefitinib-treated Japanese lung cancer patients by Nyberg, Fredrik, Ogiwara, Atsushi, Harbron, Chris G, Kawakami, Takao, Nagasaka, Keiko, Takami, Sachiko, Wada, Kazuya, Tu, Hsiao-Kun, Otsuji, Makiko, Kyono, Yutaka, Dobashi, Tae, Komatsu, Yasuhiko, Kihara, Makoto, Akimoto, Shingo, Peers, Ian S, South, Marie C, Higenbottam, Tim, Fukuoka, Masahiro, Nakata, Koichiro, Ohe, Yuichiro, Kudoh, Shoji, Clausen, Ib Groth, Nishimura, Toshihide, Marko-Varga, György, Kato, Harubumi

“…Interstitial lung disease (ILD) events have been reported in Japanese non-small-cell lung cancer (NSCLC) patients receiving EGFR tyrosine kinase inhibitors. We…”
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Biodistribution and dosimetry of (99m)Tc-RP527, a gastrin-releasing peptide (GRP) agonist for the visualization of GRP receptor-expressing malignancies by Van de Wiele, C, Dumont, F, Dierckx, R A, Peers, S H, Thornback, J R, Slegers, G, Thierens, H

“…The aim of this study was to determine the human biodistribution and radiation dosimetry of (99m)Tc-RP527, a promising radioligand for the visualization of…”
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Characterisation of the guinea pig model of osteoarthritis by in vivo three-dimensional magnetic resonance imaging by Tessier, J.J, Bowyer, J, Brownrigg, N.J, Peers, I.S, Westwood, F.R, Waterton, J.C, Maciewicz, R.A

“…Objective: To characterise longitudinal changes in joint integrity and cartilage volume in vivo in the guinea pig spontaneous osteoarthritis (OA) model by…”
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In search of preclinical robustness by Peers, Ian S., Ceuppens, Peter R., Harbron, Chris

“…Systematic engagement of statisticians in preclinical research could help address the weaknesses that are undermining the likelihood of subsequent success in…”
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The Future of EU Treaty Amendments by Peers, Steve

“…Given the continued relevance of the issue of Treaty amendments and the complexity of the legal issues resulting from the different forms of Treaty amendment,…”
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Personalized Medicine and Proteomics:  Lessons from Non-Small Cell Lung Cancer by Marko-Varga, György, Ogiwara, Atsushi, Nishimura, Toshihide, Kawamura, Takeshi, Fujii, Kiyonaga, Kawakami, Takao, Kyono, Yutaka, Tu, Hsiao-kun, Anyoji, Hisae, Kanazawa, Mitsuhiro, Akimoto, Shingo, Hirano, Takashi, Tsuboi, Masahiro, Nishio, Kazuto, Hada, Shuji, Jiang, Haiyi, Fukuoka, Masahiro, Nakata, Kouichiro, Nishiwaki, Yutaka, Kunito, Hideo, Peers, Ian S, Harbron, Chris G, South, Marie C, Higenbottam, Tim, Nyberg, Fredrik, Kudoh, Shoji, Kato, Harubumi

“…Personalized medicine allows the selection of treatments best suited to an individual patient and disease phenotype. To implement personalized medicine,…”
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Is there a role for agonist gastrin-releasing peptide receptor radioligands in tumour imaging? by VAN DE WIELE, C, DUMONT, F, VAN BELLE, S, SLEGERS, G, PEERS, S H, DIERCKX, R A

“…Gastrin-releasing peptide (GRP) has been shown to be a tumour growth stimulating agent for a number of normal and human cancer cell lines. The tumour growth…”
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Can you trust your animal study data? by Peers, Ian S., South, Marie C., Ceuppens, Peter R., Bright, Jonathan D., Pilling, Elizabeth

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Single Dose of the Antivascular Agent, ZD6126 (N-Acetylcoichinol-O-Phosphate), Reduces Perfusion for at Least 96 Hours in the GH3 Prolactinoma Rat Tumor Model by McIntyre, Dominick J.O., Robinson, Simon P., Howe, Franklyn A., Griffiths, John R., Ryan, Anderson J., Blakey, David C., Peers, Ian S., Waterton, John C.

“…Tumor vasculature is an attractive therapeutic target as it differs structurally from normal vasculature, and the destruction of a single vessel can lead to…”
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Human Recombinant Lipocortin 1 Has Acute Local Anti-Inflammatory Properties in the Rat Paw Edema Test by Cirino, G., Peers, S. H., Flower, R. J., Browning, J. L., Pepinsky, R. B.

“…Human recombinant lipocortin 1 has been tested for anti-inflammatory activity in a conventional model of acute inflammation. Microgram amounts of the protein,…”
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ASSAY OPTIMIZATION AND REGULATION OF UREASE ACTIVITY IN TWO MARINE DIATOMS by Peers, Graham S., Milligan, Allen J., Harrison, Paul J.

“…An in vitro urease enzyme assay was developed for the marine diatoms Thalassiosira pseudonana Hasle et Heimdal (clone 3H) and T. weissflogii (Grunow) Fryxell…”
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Protection from neurodegeneration in the 6-hydroxydopamine (6-OHDA) model of Parkinson's with novel 1-hydroxypyridin-2-one metal chelators by Workman, David G, Tsatsanis, Andrew, Lewis, Frank W, Boyle, John P, Mousadoust, Maryam, Hettiarachchi, Nishani T, Hunter, Michael, Peers, Chris S, Tétard, David, Duce, James A

“…Brain iron accumulation has been associated with inciting the generation of oxidative stress in a host of chronic neurological diseases, including Parkinson's…”
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Ca(2+) stores and capacitative Ca(2+) entry in human neuroblastoma (SH-SY5Y) cells expressing a familial Alzheimer's disease presenilin-1 mutation by Smith, I F, Boyle, J P, Vaughan, P F T, Pearson, H A, Cowburn, R F, Peers, C S

“…Presenilins are involved in the proteolytic production of Alzheimer's amyloid peptides, but are also known to regulate Ca(2+) homeostasis in various cells…”
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Anti-inflammatory lipocortin 1 production by peripheral blood leucocytes in response to hydrocortisone by Goulding, N J, Godolphin, J L, Sharland, P R, Peers, S H, Sampson, M, Maddison, P J, Flower, R J

“…The presence and amount of the anti-inflammatory protein lipocortin 1 was determined in plasma and peripheral blood leucocytes by a highly specific,…”
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Sex steroids affect glucocorticoid response to chronic inflammation and to interleukin-1 by Da Silva, J A, Peers, S H, Perretti, M, Willoughby, D A

“…The influence of gender and sex hormones upon both the hypothalamic-pituitary-adrenal (HPA) axis and the immune and inflammatory responses is well recognized,…”
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Serum corticosterone, interleukin‐1 and tumour necrosis factor in rat experimental endotoxaemia: comparison between Lewis and Wistar strains by Perretti, M., Duncan, G.S., Flower, R.J., Peers, S.H.

“…1 Circulating corticosterone, interleukin‐1 (IL‐1) and tumour necrosis factor‐α (TNFα) activities in serum of Lewis and Wistar rats were measured following…”
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