Search Results - "Peeper, D.S."

Oncogene-Induced Cell Senescence — Halting on the Road to Cancer by Mooi, W.J, Peeper, D.S

“…This review of oncogene-induced cell senescence describes a physiological mechanism that provides protection against cancer. The mechanisms underlying the…”
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The (re)discovery of tumor-intrinsic determinants of immune sensitivity by functional genetic screens by Vredevoogd, D.W., Apriamashvili, G., Peeper, D.S.

“…Functional genetic screens by CRISPR-Cas9 allow for the unbiased discovery of proteins causally involved in complex biological processes. In recent years, this…”
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A Twist – Snail axis critical for TrkB-induced metastasis by Geiger, T.R, Smit, M.A, Peeper, D.S

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A‐ and B‐type cyclins differentially modulate substrate specificity of cyclin‐cdk complexes by Peeper, D.S., Parker, L.L., Ewen, M.E., Toebes, M., Hall, F.L., Xu, M., Zantema, A., Eb, A.J., Piwnica‐Worms, H.

“…Both cyclins A and B associate with and thereby activate cyclin‐dependent protein kinases (cdks). We have investigated which component in the cyclin‐cdk…”
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Zeb1 is required for TrkB-induced epithelial-mesenchymal transition, anoikis resistance and metastasis by Smit, M A, Peeper, D S

“…Anoikis (detachment-induced apoptosis) prevents the survival of cells at inappropriate sites of the body and can therefore act as a barrier to metastasis. In a…”
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in benign and malignant human tumours by Michaloglou, C, Vredeveld, L.C.W, Mooi, W.J, Peeper, D.S

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