Search Results - "Peel, Emma"
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Platypus and echidna genomes reveal mammalian biology and evolution
Published in Nature (London) (29-04-2021)“…Egg-laying mammals (monotremes) are the only extant mammalian outgroup to therians (marsupial and eutherian animals) and provide key insights into mammalian…”
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2
Tasmanian devil cathelicidins exhibit anticancer activity against Devil Facial Tumour Disease (DFTD) cells
Published in Scientific reports (04-08-2023)“…The Tasmanian devil ( Sarcophilus harrisii ) is endangered due to the spread of Devil Facial Tumour Disease (DFTD), a contagious cancer with no current…”
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3
Multi-omics resources for the Australian southern stuttering frog (Mixophyes australis) reveal assorted antimicrobial peptides
Published in Scientific reports (18-02-2024)“…The number of genome-level resources for non-model species continues to rapidly expand. However, frog species remain underrepresented, with up to 90% of frog…”
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4
Koala cathelicidin PhciCath5 has antimicrobial activity, including against Chlamydia pecorum
Published in PloS one (14-04-2021)“…Devastating fires in Australia over 2019-20 decimated native fauna and flora, including koalas. The resulting population bottleneck, combined with significant…”
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5
Bioluminescent murine models of bacterial sepsis and scald wound infections for antimicrobial efficacy testing
Published in PloS one (16-07-2018)“…There are very few articles in the literature describing continuous models of bacterial infections that mimic disease pathogenesis in humans and animals…”
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6
Metapopulation management of a critically endangered marsupial in the age of genomics
Published in Global ecology and conservation (01-11-2021)“…The value of genetic management is increasingly recognised in natural resource management particularly in relation to threatened species conservation and…”
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A reference genome for the critically endangered woylie, Bettongia penicillata ogilbyi
Published in GigaByte (Hong Kong, China) (10-12-2021)“…Biodiversity is declining globally, and Australia has one of the worst extinction records for mammals. The development of sequencing technologies means that…”
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A reference genome, mitochondrial genome and associated transcriptomes for the critically endangered swift parrot ( Lathamus discolor) [version 1; peer review: awaiting peer review]
Published in F1000 research (2024)“…Abstract* The swift parrot ( Lathamus discolor) is a Critically Endangered migratory parrot that breeds in Tasmania and winters on the Australian mainland…”
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9
Genome assembly of the numbat ( Myrmecobius fasciatus ), the only termitivorous marsupial
Published in GigaByte (Hong Kong, China) (17-03-2022)“…The numbat ( ) is an endangered Australian marsupial, and the last surviving member of the Myrmecobiidae family. The numbat regularly undergoes torpor and is…”
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10
Characterisation of defensins across the marsupial family tree
Published in Developmental and comparative immunology (01-09-2024)“…Defensins are antimicrobial peptides involved in innate immunity, and gene number differs amongst eutherian mammals. Few studies have investigated defensins in…”
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11
Lessons learnt from the Tasmanian devil facial tumour regarding immune function in cancer
Published in Mammalian genome (01-12-2018)“…Genetic and genomic technologies have facilitated a greater understanding of the Tasmanian devil immune system and the origins, evolution and spread of devil…”
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12
The Value of Reference Genomes in the Conservation of Threatened Species
Published in Genes (25-10-2019)“…Conservation initiatives are now more crucial than ever-over a million plant and animal species are at risk of extinction over the coming decades. The genetic…”
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13
Adaptation and conservation insights from the koala genome
Published in Nature genetics (01-08-2018)“…The koala, the only extant species of the marsupial family Phascolarctidae, is classified as ‘vulnerable’ due to habitat loss and widespread disease. We…”
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14
Annotation of immune genes in the extinct thylacine (Thylacinus cynocephalus)
Published in Immunogenetics (New York) (01-06-2021)“…Advances in genome sequencing technology have enabled genomes of extinct species to be sequenced. However, given the fragmented nature of these genome…”
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15
Marsupial and monotreme cathelicidins display antimicrobial activity, including against methicillin-resistant Staphylococcus aureus
Published in Microbiology (Society for General Microbiology) (01-10-2017)“…With the growing demand for new antibiotics to combat increasing multi-drug resistance, a family of antimicrobial peptides known as cathelicidins has emerged…”
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16
Best genome sequencing strategies for annotation of complex immune gene families in wildlife
Published in Gigascience (30-10-2022)“…Abstract Background The biodiversity crisis and increasing impact of wildlife disease on animal and human health provides impetus for studying immune genes in…”
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17
Genomic insights into a contagious cancer in Tasmanian devils
Published in Trends in genetics (01-09-2015)“…Highlights • Utilisation of genetics and genomics techniques has driven our understanding of a contagious cancer in Tasmanian devils. • Karyotyping and…”
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18
Significant decline in anticancer immune capacity during puberty in the Tasmanian devil
Published in Scientific reports (16-03-2017)“…Tasmanian devils ( Sarcophilus harrisii ) are at risk of extinction in the wild due to Devil Facial Tumour Disease (DFTD), a rare contagious cancer. The…”
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19
A reference genome, mitochondrial genome and associated transcriptomes for the critically endangered swift parrot ( Lathamus discolor) [version 2; peer review: 2 approved with reservations]
Published in F1000 research (01-01-2024)“…Abstract* The swift parrot ( Lathamus discolor) is a Critically Endangered migratory parrot that breeds in Tasmania and winters on the Australian mainland…”
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20
Structure-activity analysis of peptidic Chlamydia HtrA inhibitors
Published in Bioorganic & medicinal chemistry (15-09-2019)“…[Display omitted] Chlamydia trachomatis high temperature requirement A (CtHtrA) is a serine protease that performs proteolytic and chaperone functions in…”
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