Search Results - "Peek, Mary E"
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Cytotoxic effects of cytoplasmic-targeted and nuclear-targeted gold and silver nanoparticles in HSC-3 cells – A mechanistic study
Published in Toxicology in vitro (01-06-2015)“…[Display omitted] •Nuclear-targeted NPs showed increased uptake and cytotoxicity in HSC-3 cells.•Nuclear-targeted AuNP exposure induced a quiescent cellular…”
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Pyoverdine, the Major Siderophore in Pseudomonas aeruginosa, Evades NGAL Recognition
Published in Interdisciplinary Perspectives on Infectious Diseases (2012)“…Pseudomonas aeruginosa is the most common pathogen that persists in the cystic fibrosis lungs. Bacteria such as P. aeruginosa secrete siderophores…”
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Determination of soluble and membrane protein structures by X-ray crystallography
Published in Methods in molecular biology (Clifton, N.J.) (2013)“…X-ray crystallography is a technique used to determine the atomic-detail structure of a biological macromolecule. The method relies on the ability to generate…”
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Structure of a DNA−Porphyrin Complex
Published in Biochemistry (Easton) (05-03-1996)“…We report the 2.4 Å resolution X-ray structure of a complex in which a small molecule flips a base out of a DNA helical stack. The small molecule is a…”
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Effects of cationic charge on three-dimensional structures of intercalative complexes: structure of a bis-intercalated DNA complex solved by MAD phasing
Published in Current medicinal chemistry (01-01-2000)“…We characterize intercalative complexes as either "high charge" and "low charge". In low charge complexes, stacking interactions appear to dominate stability…”
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