Search Results - "Pedrosa, R. C."

Molecular chaperone Hsp90 as a target for oxidant-based anticancer therapies by Beck, R, Dejeans, N, Glorieux, C, Pedrosa, R C, Vásquez, D, Valderrama, J A, Calderon, P B, Verrax, J

“…Hsp90 is a molecular chaperone involved in the stabilization of many oncoproteins that are required for the acquisition and maintenance of the so-called six…”
Get more information

Effect of different oxygen tensions on weight gain, feed conversion, and antioxidant status in piapara, Leporinus elongatus (Valenciennes, 1847) by Wilhelm Filho, D., Torres, M.A., Zaniboni-Filho, E., Pedrosa, R.C.

“…Juvenile piapara ( Leporinus elongatus) were progressively exposed to several levels of dissolved oxygen for 28 days, severe hypoxia, moderate hypoxia and…”
Get full text

Time-course variations of DNA damage and biomarkers of oxidative stress in tilapia (Oreochromis niloticus) exposed to effluents from a swine industry by LIMA, P. L, BENASSI, J. C, PEDROSA, R. C, DAL MAGRO, J, OLIVEIRA, T. B, FILHO, D. Wilhelm

“…DNA damage (Comet assay), lipoperoxidation levels (TBARS), and several biomarkers of oxidative stress such as catalase (CAT), glutathione reductase (GR),…”
Get full text

Influence of season and pollution on the antioxidant defenses of the cichlid fish acará (Geophagus brasiliensis) by Wilhelm Filho, D, Torres, M A, Tribess, T B, Pedrosa, R C, Soares, C H

“…The livers of Geophagus brasiliensis collected from both a non-polluted site and a polluted site were analyzed for different antioxidant defenses, O2…”
Get full text

USE OF COAL MINING WASTE FOR THE REMOVAL OF ACIDITY AND METAL IONS AL (III), FE (III) AND MN (II) IN ACID MINE DRAINAGE by Geremias, R., Laus, R., Macan, J. M., Pedrosa, R. C., Laranjeira, M. C. M., Silvano, J., Fávere, F. V.

“…The coal industry may generate acid mine drainage (AMD) and mining wastes, which may adversely affect the quality of the environment. In this study we propose…”
Get full text

Phenolic profile and effect of regular consumption of Brazilian red wines on in vivo antioxidant activity by Gris, E.F., Mattivi, F., Ferreira, E.A., Vrhovsek, U., Filho, D.W., Pedrosa, R.C., Bordignon-Luiz, M.T.

“…In this study, Vitis vinifera L wines cv. Cabernet Franc, Merlot, Sangiovese and Syrah, 2006 and 2007 vintages, produced in São Joaquim, a new wine-producing…”
Get full text

Albendazole as a promising molecule for tumor control by Castro, L S E P W, Kviecinski, M R, Ourique, F, Parisotto, E B, Grinevicius, V M A S, Correia, J F G, Wilhelm Filho, D, Pedrosa, R C

“…This work evaluated the antitumor effects of albendazole (ABZ) and its relationship with modulation of oxidative stress and induction of DNA damage. The…”
Get full text

Lipid lowering activity of hydrosoluble chitosan and association with Aloe vera L. and Brassica olearaceae L by Geremias, R, Pedrosa, R.C, Locatelli, C, Favere, V.T. de, Coury-Pedrosa, R, Laranjeira, M.C.M

“…The lipid lowering activity of chitosan associated with Aloe vera L. or hydrosoluble chitosan with Brassica olearaceae L. has been studied in rats. In this…”
Get full text

Evaluation of Remediation of Coal Mining Wastewater by Chitosan Microspheres Using Biomarkers by Benassi, J. C, Laus, R, Geremias, R, Lima, P. L, Menezes, C. T. B, Laranjeira, M. C. M, Wilhelm-Filho, D, Fávere, V. T, Pedrosa, R. C

“…Acidic mine waters have a marked influence on the surrounding environment and pose a serious threat through long-term environmental degradation. Therefore, it…”
Get full text

Hypolipidaemic activity of methanol extract of Aleurites moluccana by Pedrosa, R. C., Meyre-Silva, C., Cechinel-Filho, V., Benassi, J. C., Oliveira, L. F. S., Zancanaro, V., Dal Magro, J., Yunes, R. A.

“…The lipid‐lowering action of the leaves of the Aleurites moluccana methanol extract was studied in Triton W‐1339 and high‐fat‐diet fed rats. The serum lipids…”
Get full text

A Novel Combined Approach of Short-Chain Sphingolipids and Thermosensitive Liposomes for Improved Drug Delivery to Tumor Cells by Haeri, Azadeh, Pedrosa, Lilia R C, Ten Hagen, Timo L M, Dadashzadeh, Simin, Koning, Gerben A

“…Despite the advantages of liposomal drug delivery, the bioavailability of the chemotherapeutic drugs to tumor cells is limited by their slow release from…”
Get more information

Inhibition of cell proliferation and migration by oxidative stress from ascorbate-driven juglone redox cycling in human bladder-derived T24 cells by Kviecinski, M.R., Pedrosa, R.C., Felipe, K.B., Farias, M.S., Glorieux, C., Valenzuela, M., Sid, B., Benites, J., Valderrama, J.A., Verrax, J., Buc Calderon, P.

“…[Display omitted] ► The cytotoxicity of juglone is markedly increased by ascorbate. ► T24 cell death by oxidative stress is necrosis-like. ► Redox cycling by…”
Get full text

Use of Chitosan Microspheres As Remedial Material For Acidity and Iron (III) Contents Of Coal Mining Wastewaters by Fávere, V.T., Laus, R., Laranjeira, M.C.M., Martins, A.O., Pedrosa, R.C.

“…Chitosan microspheres are highly effective in neutralizing the acidity of wastewaters from coal mining. The saturation capacity for the formation of a…”
Get full text

Antiproliferative effects of phenylaminonaphthoquinones are increased by ascorbate and associated with the appearance of a senescent phenotype in human bladder cancer cells by Felipe, K.B., Benites, J., Glorieux, C., Sid, B., Valenzuela, M., Kviecinski, M.R., Pedrosa, R.C., Valderrama, J.A., Levêque, Ph, Gallez, B., Verrax, J., Buc Calderon, P.

“…•Phenylaminonaphthoquinones are redox cyclers able to form ROS.•Phenylaminonaphthoquinones plus ascorbate inhibit T24 cell growth.•Phenylaminonaphthoquinones…”
Get full text

Remediation of coal mining wastewaters using chitosan microspheres by Geremias, R., Pedrosa, R. C., Benassi, J. C., Fávere, V. T., Stolberg, J., Menezes, C. T. B., Laranjeira, M. C. M.

“…This study aimed to evaluate the potential use of chitosan and chitosan/poly(vinylalcohol) microspheres incorporating with tetrasulphonated copper (II)…”
Get full text

SFE from Bidens pilosa Linné to obtain extracts rich in cytotoxic polyacetylenes with antitumor activity by Kviecinski, M.R., Benelli, P., Felipe, K.B., Correia, J.F.G., Pich, C.T., Ferreira, S.R.S., Pedrosa, R.C.

“…Bidens pilosa L. is a plant considered medicinal by some South American cultures. It contains polyacetylenes which may be the constituents responsible for its…”
Get full text

Sera from chronic chagasic patients with complex cardiac arrhythmias depress electrogenesis and conduction in isolated rabbit hearts by FARIAS DE OLIVEIRA, S, PEDROSA, R. C, NASCIMENTO, J. H. M, CAMPOS DE CARVALHO, A. C, MASAKO OYA MASUDA

“…Immune dysfunction has long been proposed as a mechanism for the etiopathogenesis of the chronic phase of Chagas' disease. Antibodies of chagasic patients have…”
Get full text

Saliva ELISA: a method for the diagnosis of chronic Chagas disease in endemic areas by Pinho, R.T., Pedrosa, R.C., Costa-Martins, P., Castello-Branco, L.R.R

“…An indirect enzyme linked immunosorbent assay (ELISA) was applied to saliva to detect chronic infection by Trypanosoma cruzi in humans. Saliva samples from 114…”
Get full text

Time-dependent oxidative stress caused by benznidazole by Pedrosa, R C, De Bem, A F, Locatelli, C, Pedrosa, R C, Geremias, R, Wilhelm Filho, D

“…Benznidazole (BZN) is a nitroimidazole derivative which has a notable trypanocide activity, and it is the only drug used in Brazil and Argentina for the…”
Get more information

Analysis and partial epitope mapping of human T cell responses to Trypanosoma cruzi cysteinyl proteinase by Arnholdt, AC, Piuvezam, MR, Russo, DM, Lima, AP, Pedrosa, RC, Reed, SG, Scharfstein, J

“…Human infection with Trypanosoma cruzi (Chagas' disease) is usually accompanied by humoral and cellular immune responses to GP57/51, a major antigen that was…”
Get full text