Search Results - "Pedretti, Sarah"

HDL protects against myocardial ischemia reperfusion injury via miR-34b and miR-337 expression which requires STAT3 by Pedretti, Sarah, Brulhart-Meynet, Marie-Claude, Montecucco, Fabrizio, Lecour, Sandrine, James, Richard W, Frias, Miguel A

“…High density lipoprotein (HDL) protects against myocardial infarction via mechanisms that remain unclear. STAT3 (signal transducer and activator of…”
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Pharmacological Intervention to Modulate HDL: What Do We Target? by Woudberg, Nicholas J, Pedretti, Sarah, Lecour, Sandrine, Schulz, Rainer, Vuilleumier, Nicolas, James, Richard W, Frias, Miguel A

“…The cholesterol concentrations of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) have traditionally served as risk factors for cardiovascular…”
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Dose Dependent Antimicrobial Cellular Cytotoxicity-Implications for ex vivo Diagnostics by Copaescu, Ana, Choshi, Phuti, Pedretti, Sarah, Mouhtouris, Effie, Peter, Jonathan, Trubiano, Jason A

“…and diagnostics, such as interferon-γ (IFN-γ) release enzyme linked ImmunoSpot (ELISpot) and flow cytometry, are increasingly employed in the research and…”
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Skin infiltrating T-cell profile of drug reaction with eosinophilia and systemic symptoms (DRESS) reactions among HIV-infected patients by Chimbetete, Tafadzwa, Choshi, Phuti, Pedretti, Sarah, Porter, Mireille, Roberts, Riyaadh, Lehloenya, Rannakoe, Peter, Jonathan

“…Drug Reaction with Eosinophilia Systemic Symptoms (DRESS) is more common in persons living with HIV (PLHIV), and first-line anti-TB drugs (FLTDs) and…”
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Corrigendum: Dose Dependent Antimicrobial Cellular Cytotoxicity—Implications for ex vivo Diagnostics by Copaescu, Ana, Choshi, Phuti, Pedretti, Sarah, Mouhtouris, Effie, Peter, Jonathan, Trubiano, Jason A.

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Improving reconstituted HDL composition for efficient post-ischemic reduction of ischemia reperfusion injury by Brulhart-Meynet, Marie-Claude, Braunersreuther, Vincent, Brinck, Jonas, Montecucco, Fabrizio, Prost, Jean-Christophe, Thomas, Aurelien, Galan, Katia, Pelli, Graziano, Pedretti, Sarah, Vuilleumier, Nicolas, Mach, François, Lecour, Sandrine, James, Richard W, Frias, Miguel A

“…New evidence shows that high density lipoproteins (HDL) have protective effects beyond their role in reverse cholesterol transport. Reconstituted HDL (rHDL)…”
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HDL protects against ischemia reperfusion injury by preserving mitochondrial integrity by Frias, Miguel A, Pedretti, Sarah, Hacking, Damian, Somers, Sarin, Lacerda, Lydia, Opie, Lionel H, James, Richard W, Lecour, Sandrine

“…Abstract Objective High density lipoproteins (HDL) protect against ischemia reperfusion injury (IRI). However the precise mechanisms are not clearly…”
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Rooibos herbal tea reduces allergic basophil activation in adult atopic patients by Pedretti, Sarah, Peter, Jonny

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Clinical profiles and HLA haplotypes in patients with severe cutaneous adverse reactions in Lusaka, Zambia by Zulu, Andrew, Pedretti, Sarah, Choshi, Phuti, Peter, Jonathan, Ngalamika, Owen

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High density lipoprotein/sphingosine-1-phosphate-induced cardioprotection: Role of STAT3 as part of the SAFE pathway by Frias, Miguel A., Lecour, Sandrine, James, Richard W., Pedretti, Sarah

“…High density lipoprotein (HDL) cholesterol has beneficial effects beyond its atheroprotective function in reverse cholesterol transport, including…”
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HIV-Associated Immune Dysregulation in the Skin: A Crucible for Exaggerated Inflammation and Hypersensitivity by Chimbetete, Tafadzwa, Buck, Chloe, Choshi, Phuti, Selim, Rose, Pedretti, Sarah, Divito, Sherrie Jill, Phillips, Elizabeth Jane, Lehloenya, Rannakoe, Peter, Jonny

“…Skin diseases are hallmarks of progressive HIV-related immunosuppression, with severe noninfectious inflammatory and hypersensitivity conditions as common as…”
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Early Use Of Intravenous Methylprednisolone Attenuates Positive Challenge Reactions During Sequential Additive Drug Challenge by Thwala, Bukiwe, Teixeira, Nadine, Mpungose, Aneliswa, Porter, Mireille, Pedretti, Sarah, Selim, Rose, Zulu, Andrew, Ngalamika, Owen, Lehloenya, Rannakoe, Peter, Jonathan

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IFN-γ ELISpot in Severe Cutaneous Adverse Reactions to First-Line Antituberculosis Drugs in an HIV Endemic Setting by Porter, Mireille, Choshi, Phuti, Pedretti, Sarah, Chimbetete, Tafadzwa, Smith, Rhodine, Meintjes, Graeme, Phillips, Elizabeth, Lehloenya, Rannakoe, Peter, Jonny

“…Severe cutaneous adverse reactions related to first-line antituberculosis drugs are associated with high mortality and long-term morbidity. Oral sequential…”
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STAT3α interacts with nuclear GSK3beta and cytoplasmic RISK pathway and stabilizes rhythm in the anoxic-reoxygenated embryonic heart by Pedretti, Sarah, Raddatz, Eric

“…Activation of the Janus Kinase 2/Signal Transducer and Activator of Transcription 3 (JAK2/STAT3) pathway is known to play a key role in cardiogenesis and to…”
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Interplay between the SAFE and the sphingolipid pathway for cardioprotection by Cour, Martin, Pedretti, Sarah, Nduhirabandi, Frederic, Hacking, Damian, Frias, Miguel A., Hausenloy, Derek J., Lecour, Sandrine

“…Activation of both the Survivor Activating Factor Enhancement (SAFE) pathway (including Tumor Necrosis Factor-alpha (TNF-α) and Signal Transducer and Activator…”
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Dose Dependent Antimicrobial Cellular Cytotoxicity – Implications for ex vivo diagnostics by Copaescu, Ana, Choshi, Phuti, Pedretti, Sarah, Mouhtouris, Effie, Peter, Jonny, Trubiano, Jason

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PA-631 The immunopathogenic mechanisms of severe cutaneous adverse drug reactions to first line anti-tuberculosis drugs by Chosi, Phuti, Pedretti, Sarah, Lehloenya, Rannakoe, Phillips, Elizabeth, Peter, Jonathan

“…BackgroundFirst-line anti-tuberculosis drugs (FLTD) are the commonest cause of severe immune-mediated adverse drug reactions, including SJS/TEN and DRESS in…”
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STAT3[alpha] interacts with nuclear GSK3beta and cytoplasmic RISK pathway and stabilizes rhythm in the anoxic-reoxygenated embryonic heart by Pedretti, Sarah, Raddatz, Eric

“…Activation of the Janus Kinase 2/Signal Transducer and Activator of Transcription 3 (JAK2/STAT3) pathway is known to play a key role in cardiogenesis and to…”
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Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson syndrome and toxic epidermal necrolysis by Gibson, Andrew, Ram, Ramesh, Gangula, Rama, Li, Yueran, Mukherjee, Eric, Palubinsky, Amy M., Campbell, Chelsea N., Thorne, Michael, Konvinse, Katherine C., Choshi, Phuti, Deshpande, Pooja, Pedretti, Sarah, Fear, Mark W., Wood, Fiona M., O’Neil, Richard T., Wanjalla, Celestine N., Kalams, Spyros A., Gaudieri, Silvana, Lehloenya, Rannakoe J., Bailin, Samuel S., Chopra, Abha, Trubiano, Jason A., Peter, Jonny G., Mallal, Simon A., Phillips, Elizabeth J.

“…Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is a rare but life-threatening cutaneous drug reaction mediated by human leukocyte antigen…”
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Adenosine A1 receptor activation is arrhythmogenic in the developing heart through NADPH oxidase/ERK- and PLC/PKC-dependent mechanisms by Robin, Elodie, Sabourin, Jessica, Benoit, Rachel, Pedretti, Sarah, Raddatz, Eric

“…Abstract Whether adenosine, a crucial regulator of the developing cardiovascular system, can provoke arrhythmias in the embryonic/fetal heart remains…”
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