Search Results - "Pedrera, Miriam"

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses by Tan, Tiong Kit, Rijal, Pramila, Rahikainen, Rolle, Keeble, Anthony H., Schimanski, Lisa, Hussain, Saira, Harvey, Ruth, Hayes, Jack W. P., Edwards, Jane C., McLean, Rebecca K., Martini, Veronica, Pedrera, Miriam, Thakur, Nazia, Conceicao, Carina, Dietrich, Isabelle, Shelton, Holly, Ludi, Anna, Wilsden, Ginette, Browning, Clare, Zagrajek, Adrian K., Bialy, Dagmara, Bhat, Sushant, Stevenson-Leggett, Phoebe, Hollinghurst, Philippa, Tully, Matthew, Moffat, Katy, Chiu, Chris, Waters, Ryan, Gray, Ashley, Azhar, Mehreen, Mioulet, Valerie, Newman, Joseph, Asfor, Amin S., Burman, Alison, Crossley, Sylvia, Hammond, John A., Tchilian, Elma, Charleston, Bryan, Bailey, Dalan, Tuthill, Tobias J., Graham, Simon P., Duyvesteyn, Helen M. E., Malinauskas, Tomas, Huo, Jiandong, Tree, Julia A., Buttigieg, Karen R., Owens, Raymond J., Carroll, Miles W., Daniels, Rodney S., McCauley, John W., Stuart, David I., Huang, Kuan-Ying A., Howarth, Mark, Townsend, Alain R.

“…There is need for effective and affordable vaccines against SARS-CoV-2 to tackle the ongoing pandemic. In this study, we describe a protein nanoparticle…”
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A simple and rapid approach to develop recombinant avian herpesvirus vectored vaccines using CRISPR/Cas9 system by Tang, Na, Zhang, Yaoyao, Pedrera, Miriam, Chang, Pengxiang, Baigent, Susan, Moffat, Katy, Shen, Zhiqiang, Nair, Venugopal, Yao, Yongxiu

“…•Development of a rapid pipeline for generating recombinant HVT-based vaccines.•NHEJ repair pathway makes targeted insertion of the foreign gene more…”
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African Swine Fever Virus Infection and Cytokine Response In Vivo: An Update by Franzoni, Giulia, Pedrera, Miriam, Sánchez-Cordón, Pedro J

“…African swine fever (ASF) is a hemorrhagic viral disease of domestic pigs and wild suids (all ) caused by the ASF virus (ASFV). The disease is spreading…”
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Evaluation of the immunogenicity of an mRNA vectored Nipah virus vaccine candidate in pigs by Pedrera, Miriam, McLean, Rebecca K, Medfai, Lobna, Thakur, Nazia, Todd, Shawn, Marsh, Glenn, Bailey, Dalan, Donofrio, Gaetano, Muramatsu, Hiromi, Pardi, Norbert, Weissman, Drew, Graham, Simon P

“…Nipah virus (NiV) poses a significant threat to human and livestock populations across South and Southeast Asia. Vaccines are required to reduce the risk and…”
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Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans by Holzer, Barbara, Rijal, Pramila, McNee, Adam, Paudyal, Basudev, Martini, Veronica, Clark, Becky, Manjegowda, Tanuja, Salguero, Francisco J, Bessell, Emily, Schwartz, John C, Moffat, Katy, Pedrera, Miriam, Graham, Simon P, Noble, Alistair, Bonnet-Di Placido, Marie, La Ragione, Roberto M, Mwangi, William, Beverley, Peter, McCauley, John W, Daniels, Rodney S, Hammond, John A, Townsend, Alain R, Tchilian, Elma

“…Pigs are natural hosts for the same subtypes of influenza A viruses as humans and integrally involved in virus evolution with frequent interspecies…”
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Correction: Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans by Holzer, Barbara, Rijal, Pramila, McNee, Adam, Paudyal, Basudev, Martini, Veronica, Clark, Becky, Manjegowda, Tanuja, Salguero, Francisco J, Bessell, Emily, Schwartz, John C, Moffat, Katy, Pedrera, Miriam, Graham, Simon P, Noble, Alistair, Placido, Marie Bonnet-Di, La Ragione, Roberto M, Mwangi, William, Beverley, Peter, McCauley, John W, Daniels, Rodney S, Hammond, John A, Townsend, Alain R, Tchilian, Elma

“…[This corrects the article DOI: 10.1371/journal.ppat.1009330.]…”
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Characterization of the Protective Cellular Immune Response in Pigs Immunized Intradermally with the Live Attenuated African Swine Fever Virus (ASFV) Lv17/WB/Rie1 by Pedrera, Miriam, Soler, Alejandro, Simón, Alicia, Casado, Nadia, Pérez, Covadonga, García-Casado, María A, Fernández-Pacheco, Paloma, Sánchez-Cordón, Pedro J, Arias, Marisa, Gallardo, Carmina

“…Candidate vaccines against African swine fever virus (ASFV) based on naturally attenuated or genetically modified viruses have the potential to generate…”
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Bovine Herpesvirus-4-Vectored Delivery of Nipah Virus Glycoproteins Enhances T Cell Immunogenicity in Pigs by Pedrera, Miriam, Macchi, Francesca, McLean, Rebecca K, Franceschi, Valentina, Thakur, Nazia, Russo, Luca, Medfai, Lobna, Todd, Shawn, Tchilian, Elma Z, Audonnet, Jean-Christophe, Chappell, Keith, Isaacs, Ariel, Watterson, Daniel, Young, Paul R, Marsh, Glenn A, Bailey, Dalan, Graham, Simon P, Donofrio, Gaetano

“…Nipah virus (NiV) is an emergent pathogen capable of causing acute respiratory illness and fatal encephalitis in pigs and humans. A high fatality rate and…”
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Gallid herpesvirus 3 SB-1 strain as a recombinant viral vector for poultry vaccination by Sadigh, Yashar, Powers, Claire, Spiro, Simon, Pedrera, Miriam, Broadbent, Andrew, Nair, Venugopal

“…Live herpesvirus-vectored vaccines are widely used in veterinary medicine to protect against many infectious diseases. In poultry, three strains of herpesvirus…”
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Evaluation of the Delivery of a Live Attenuated Porcine Reproductive and Respiratory Syndrome Virus as a Unit Solid Dose Injectable Vaccine by Hayhurst, Ellie, Rose, Emily, Pedrera, Miriam, Edwards, Jane C, Kotynska, Natalia, Grainger, Daisy, Sadigh, Yashar, Flannery, John, Bonnet, Ludo, Ritwik, Ritwik, Dulal, Pawan, Howard, M. Keith, Graham, Simon P

“…Solid dose vaccine formulation and delivery systems offer potential advantages over traditional liquid vaccine formulations. In addition to enhanced…”
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Proteome-wide screening reveals immunodominance in the CD8 T cell response against classical swine fever virus with antigen-specificity dependent on MHC class I haplotype expression by Franzoni, Giulia, Kurkure, Nitin V, Essler, Sabine E, Pedrera, Miriam, Everett, Helen E, Bodman-Smith, Kikki B, Crooke, Helen R, Graham, Simon P

“…Vaccination with live attenuated classical swine fever virus (CSFV) vaccines induces a rapid onset of protection which has been associated with virus-specific…”
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Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell-cell fusion by Thakur, Nazia, Conceicao, Carina, Isaacs, Ariel, Human, Stacey, Modhiran, Naphak, McLean, Rebecca K, Pedrera, Miriam, Tan, Tiong Kit, Rijal, Pramila, Townsend, Alain, Taylor, Geraldine, Young, Paul R, Watterson, Daniel, Chappell, Keith J, Graham, Simon P, Bailey, Dalan

“…Although enveloped viruses canonically mediate particle entry through virus-cell fusion, certain viruses can spread by cell-cell fusion, brought about by…”
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Generating Recombinant Avian Herpesvirus Vectors with CRISPR/Cas9 Gene Editing by Tang, Na, Zhang, Yaoyao, Pedrera, Miriam, Chang, Pengxiang, Baigent, Susan, Moffat, Katy, Shen, Zhiqiang, Nair, Venugopal, Yao, Yongxiu

“…Herpesvirus of turkeys (HVT) is an ideal viral vector for the generation of recombinant vaccines against a number of avian diseases, such as avian influenza…”
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Correction: Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans by Barbara Holzer, Pramila Rijal, Adam McNee, Basudev Paudyal, Veronica Martini, Becky Clark, Tanuja Manjegowda, Francisco J. Salguero, Emily Bessell, John C. Schwartz, Katy Moffat, Miriam Pedrera, Simon P. Graham, Alistair Noble, Marie Bonnet-Di Placido, Roberto M. La Ragione, William Mwangi, Peter Beverley, John W. McCauley, Rodney S. Daniels, John A. Hammond, Alain R. Townsend, Elma Tchilian

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Inhibition of v- rel -Induced Oncogenesis through microRNA Targeting by Yao, Yongxiu, Zhang, Yaoyao, Tang, Na, Pedrera, Miriam, Shen, Zhiqiang, Nair, Venugopal

“…Several studies have shown that microRNA-targeting is an effective strategy for the selective control of tissue-tropism and pathogenesis of both DNA and RNA…”
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CD1− and CD1+ porcine blood dendritic cells are enriched for the orthologues of the two major mammalian conventional subsets by Edwards, Jane C., Everett, Helen E., Pedrera, Miriam, Mokhtar, Helen, Marchi, Emanuele, Soldevila, Ferran, Kaveh, Daryan A., Hogarth, Philip J., Johns, Helen L., Nunez-Garcia, Javier, Steinbach, Falko, Crooke, Helen R., Graham, Simon P.

“…Conventional dendritic cells (cDC) are professional antigen-presenting cells that induce immune activation or tolerance. Two functionally specialised…”
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Evaluation of hydrophobic chitosan-based particulate formulations of porcine reproductive and respiratory syndrome virus vaccine candidate T cell antigens by Mokhtar, Helen, Biffar, Lucia, Somavarapu, Satyanarayana, Frossard, Jean-Pierre, McGowan, Sarah, Pedrera, Miriam, Strong, Rebecca, Edwards, Jane C., Garcia-Durán, Margarita, Rodriguez, Maria Jose, Stewart, Graham R., Steinbach, Falko, Graham, Simon P.

“…•Novel biomimetic particulate formulations of PRRSV antigens evaluated in pigs.•Antibody responses elicited by both crude and defined PRRSV antigen…”
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The use of infrared thermography as a non-invasive method for fever detection in sheep infected with bluetongue virus by Pérez de Diego, Ana C., Sánchez-Cordón, Pedro J., Pedrera, Miriam, Martínez-López, Beatriz, Gómez-Villamandos, José C., Sánchez-Vizcaíno, José M.

“…Fever, which is closely linked to viraemia, is considered to be both the main and the earliest clinical sign in sheep infected with bluetongue virus (BTV). The…”
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The Non-structural Protein 5 and Matrix Protein Are Antigenic Targets of T Cell Immunity to Genotype 1 Porcine Reproductive and Respiratory Syndrome Viruses by Mokhtar, Helen, Pedrera, Miriam, Frossard, Jean-Pierre, Biffar, Lucia, Hammer, Sabine E, Kvisgaard, Lise K, Larsen, Lars E, Stewart, Graham R, Somavarapu, Satyanarayana, Steinbach, Falko, Graham, Simon P

“…The porcine reproductive and respiratory syndrome virus (PRRSV) is the cause of one of the most economically important diseases affecting swine worldwide…”
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Pulmonary intravascular macrophages regulate the pathogenetic mechanisms of pulmonary lesions during acute courses of classical swine fever by Núñez, Alejandro, Sánchez‐Cordón, Pedro J., Pedrera, Miriam, Gómez‐Villamandos, Jose C., Carrasco, Librado

“…Classical swine fever (CSF) is a highly contagious and often fatal viral disease of domestic pigs and wild boar. Pulmonary oedema and haemorrhages in lung…”
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