Search Results - "Pedró, Laura"

De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis by Laval, Thomas, Pedró-Cos, Laura, Malaga, Wladimir, Guenin-Macé, Laure, Pawlik, Alexandre, Mayau, Véronique, Yahia-Cherbal, Hanane, Delos, Océane, Frigui, Wafa, Bertrand-Michel, Justine, Guilhot, Christophe, Demangel, Caroline

“…Successful control of (Mtb) infection by macrophages relies on immunometabolic reprogramming, where the role of fatty acids (FAs) remains poorly understood…”
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Antibiotics shaping bacterial genome: deletion of an IS91 flanked virulence determinant upon exposure to subinhibitory antibiotic concentrations by Pedró, Laura, Baños, Rosa C, Aznar, Sonia, Madrid, Cristina, Balsalobre, Carlos, Juárez, Antonio

“…The nucleoid-associated proteins Hha and YdgT repress the expression of the toxin α-hemolysin. An Escherichia coli mutant lacking these proteins overexpresses…”
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First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosis by Palde, Prakash B., Bhaskar, Ashima, Pedró Rosa, Laura E., Madoux, Franck, Chase, Peter, Gupta, Vinayak, Spicer, Timothy, Scampavia, Louis, Singh, Amit, Carroll, Kate S.

“…Development of effective therapies to eradicate persistent, slowly replicating M. tuberculosis (Mtb) represents a significant challenge to controlling the…”
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Comparative profiling of HLA-DR and HLA-DQ associated factor VIII peptides presented by monocyte-derived dendritic cells by Peyron, Ivan, Hartholt, Robin B, Pedró-Cos, Laura, van Alphen, Floris, Brinke, Anja Ten, Lardy, Neubury, Meijer, Alexander B, Voorberg, Jan

“…The development of anti-factor VIII antibodies is a major complication of the treatment of patients with hemophilia A. Generation of high affinity anti-factor…”
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Luminescent Trimethoprim–Polyaminocarboxylate Lanthanide Complex Conjugates for Selective Protein Labeling and Time-Resolved Bioassays by Reddy, D. Rajasekhar, Pedró Rosa, Laura E, Miller, Lawrence W

“…Labeling proteins with long-lifetime emitting lanthanide (III) chelate reporters enables sensitive, time-resolved luminescence bioaffinity assays. Heterodimers…”
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Multiparameter Flow Cytometry Analysis of the Human Spleen Applied to Studies of Plasma-Derived EVs From Plasmodium vivax Patients by Gualdrón-López, Melisa, Díaz-Varela, Míriam, Toda, Haruka, Aparici-Herraiz, Iris, Pedró-Cos, Laura, Lauzurica, Ricardo, Lacerda, Marcus V G, Fernández-Sanmartín, Marco Antonio, Fernandez-Becerra, Carmen, Del Portillo, Hernando A

“…The spleen is a secondary lymphoid organ with multiple functions including the removal of senescent red blood cells and the coordination of immune responses…”
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Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication by Thenin-Houssier, Suzie, de Vera, Ian Mitchelle S, Pedro-Rosa, Laura, Brady, Angela, Richard, Audrey, Konnick, Briana, Opp, Silvana, Buffone, Cindy, Fuhrmann, Jakob, Kota, Smitha, Billack, Blase, Pietka-Ottlik, Magdalena, Tellinghuisen, Timothy, Choe, Hyeryun, Spicer, Timothy, Scampavia, Louis, Diaz-Griffero, Felipe, Kojetin, Douglas J, Valente, Susana T

“…The human immunodeficiency virus type 1 (HIV-1) capsid plays crucial roles in HIV-1 replication and thus represents an excellent drug target. We developed a…”
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Selective Antifolates for Chemically Labeling Proteins in Mammalian Cells by Pedró Rosa, Laura E, Reddy, D. Rajasekhar, Queener, Sherry F, Miller, Lawrence W

“…Antifolate labels: Molecules that bind specifically and with high affinity to proteins can be developed into powerful tools for chemical biology. The…”
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Facteurs de prédiction de réadmission précoce et mortalité dans l’insuffisance cardiaque dans le Service de Médecine Interne de l’Hôpital Universitaire San Carlos, Espagne by Villalba, Noel Lorenzo, Ballesteros, Belén Chiva, Álvarez, Laura De Pedro, Mainar, Pamen Delgado, Sánchez, Ángel Nieto, Martínez, Javier Marco, Manuel, Elpidio Calvo, Bailon, Manuel Méndez

“…IntroductionL’insuffisance cardiaque (IC) est un problème de santé en Espagne dont l’incidence croissante est en rapport avec le vieillissement de la…”
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Antibiotics shaping bacterial genome: deletion of an IS91 flanked virulence determinant upon exposure to suinhibitory antibiotic concentrations by Pedró, Laura, Baños Molina, Rosa Carmen, Aznar Vicente, Sonia, Madrid Xufré, Cristina, Balsalobre Parra, Carlos, Juárez Giménez, Antonio

“…The nucleoid-associated proteins Hha and YdgT repress the expression of the toxin α-hemolysin. An Escherichia coli mutant lacking these proteins overexpresses…”
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Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening by Pedró-Rosa, Laura, Buckner, Frederick S, Ranade, Ranae M, Eberhart, Christina, Madoux, Franck, Gillespie, J Robert, Koh, Cho Yeow, Brown, Steven, Lohse, Jacqueline, Verlinde, Christophe L M, Fan, Erkang, Bannister, Thomas, Scampavia, Louis, Hol, Wim G J, Spicer, Timothy, Hodder, Peter

“…Improved therapies for the treatment of Trypanosoma brucei, the etiological agent of the neglected tropical disease human African trypanosomiasis, are urgently…”
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Predictive factors of early readmission and mortality in patients with heart failure hospitalized in the Department of Internal Medicine of the San Carlos University Hospital, Spain by Villalba, Noel Lorenzo, Ballesteros, Belén Chiva, Álvarez, Laura De Pedro, Mainar, Pamen Delgado, Sánchez, Ángel Nieto, Martínez, Javier Marco, Manuel, Elpidio Calvo, Bailon, Manuel Méndez

“…Heart failure (HF) is a health problem in Spain where the prevalence rate for this disease is correlated with aging. Heart failure-related mortality and…”
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Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment by Wang, Leiming, Cheng, Chiang-Min, Qin, Jun, Xu, Mafei, Kao, Chung-Yang, Shi, Jingjing, You, Erli, Gong, Wanchun, Rosa, Laura Pedro, Chase, Peter, Scampavia, Louis, Madoux, Franck, Spicer, Timothy, Hodder, Peter, Xu, H Eric, Tsai, Sophia Y, Tsai, Ming-Jer

“…The orphan nuclear receptor COUP-TFII is expressed at a low level in adult tissues, but its expression is increased and shown to promote progression of…”
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Level of understanding and consumption of ultra-processed food in a Mediterranean population: A cross-sectional study by Pedro-Botet, Laura, Muns, Maria D., Solà, Rosa, Fontané, Laia, Climent, Elisenda, Benaiges, David, Flores-Le Roux, Juana A., Pedro-Botet, Juan

“…Since the population may not be aware of ultra-processed food (UPF) consumption as a result of ignorance or non-recognition, this study aimed to ascertain the…”
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Strategy from the inside out: lessons in creating organic growth by Irvin, Jill, Pedro, Laura, Gennaro, Paul

“…Over the past decade, many companies acquired their way to growth by developing and managing a portfolio of businesses, treating each as an autonomous unit…”
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Structure-based drug design against Trypanosoma brucei methionyl-tRNA synthetase by Koh, Cho Yeow, Nguyen, Jasmine, Shibata, Sayaka, Zhang, Zhongsheng, Ranade, Ranae, Gillespie, J. Robert, Hodder, Peter, Pedro-Rosa, Laura, Bannister, Thomas, Buckner, Frederick, Verlinde, Christophe, Fan, Erkang, Hol, Wim

“…Abstract only Infection by the protozoan parasite Trypanosoma brucei causes human African trypanosomiasis, commonly known as sleeping sickness. The disease is…”
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Strategy from the inside out: lessons in creating organic growth by Irvin, Jill, Pedro, Laura, Gennaro, Paul

“…Over the past decade, many companies acquired their way to growth by developing and managing a portfolio of businesses, treating each as an autonomous unit…”
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Antifolates as Tools for Chemical Biology by Pedro-Rosa, Laura E

“…Small molecule ligands and receptor protein pairs that associate to the exclusion of all other environmental components can be used as powerful biotechnology…”
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Strategy from the inside out lessons in creating organic growth by Irvin, Jill, Pedro, Laura, Gennaro, Paul

“…Over the past decade, many companies acquired their way to growth by developing and managing a portfolio of businesses, treating each as an autonomous unit…”
Get full text

Antifolates as Tools for Chemical Biology by Pedro-Rosa, Laura E

“…Small molecule ligands and receptor protein pairs that associate to the exclusion of all other environmental components can be used as powerful biotechnology…”
Get full text