Search Results - "Pedot, Gloria"

USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth by Gierisch, Maria E., Pedot, Gloria, Walser, Franziska, Lopez-Garcia, Laura A., Jaaks, Patricia, Niggli, Felix K., Schäfer, Beat W.

“…Ewing sarcoma is the second most common pediatric bone and soft tissue tumor presenting with an aggressive behavior and prevalence to metastasize. The…”
Get full text

YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells by Bierbaumer, Lisa, Katschnig, Anna M., Radic-Sarikas, Branka, Kauer, Maximilian O., Petro, Jeffrey A., Högler, Sandra, Gurnhofer, Elisabeth, Pedot, Gloria, Schäfer, Beat W., Schwentner, Raphaela, Mühlbacher, Karin, Kromp, Florian, Aryee, Dave N. T., Kenner, Lukas, Uren, Aykut, Kovar, Heinrich

“…Ewing sarcoma (EwS) is a highly metastatic bone cancer characterized by the ETS fusion oncoprotein EWS-FLI1. EwS cells are phenotypically highly plastic and…”
Get full text

Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization by Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P, Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A, Niggli, Felix K, Schäfer, Beat W

“…Oncogenic transcription factors lacking enzymatic activity or targetable binding pockets are typically considered "undruggable". An example is provided by the…”
Get full text

CRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma by Saratov, Vadim, Ngo, Quy A., Pedot, Gloria, Sidorov, Semjon, Wachtel, Marco, Niggli, Felix K., Schäfer, Beat W.

“…As the second most common pediatric bone and soft tissue tumor, Ewing sarcoma (ES) is an aggressive disease with a pathognomonic chromosomal translocation…”
Get full text

Corrigendum to "Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization" [Neoplasia volume 27 (2022) pp. 100784/Number C] by Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P, Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A, Niggli, Felix K, Schäfer, Beat W

Get full text

Author Correction: CRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma by Saratov, Vadim, Ngo, Quy A., Pedot, Gloria, Sidorov, Semjon, Wachtel, Marco, Niggli, Felix K., Schäfer, Beat W.

Get full text

Abstract 3109: Protein stability screen to identify compounds destabilizing EWS-FLI1 in Ewing sarcoma by Pedot, Gloria, Niggli, Felix K., Schaefer, Beat W.

“…Abstract Ewing sarcoma is an aggressive pediatric bone and soft tissue tumor driven by the expression of a fusion oncoprotein named EWS-FLI1, which acts as an…”
Get full text

Abstract B19: Identification of physiologically relevant EWS-FLI1 target genes in Ewing’s sarcoma via CRISPRa screening by Saratov, Vadim, Ngo, Qui A., Pedot, Gloria, Niggli, Felix K., Schaefer, Beat W.

“…Abstract Ewing’s sarcoma is an aggressive pediatric bone and soft-tissue cancer with a pathognomonic chromosomal translocation t(11;22) resulting in expression…”
Get full text

The Chromatin Remodeler CHD4 Sustains Ewing Sarcoma Cell Survival by Controlling Global Chromatin Architecture by Graca Marques, Joana, Pavlovic, Blaz, Ngo, Quy A, Pedot, Gloria, Roemmele, Michaela, Volken, Larissa, Kisele, Samanta, Perbet, Romain, Wachtel, Marco, Schäfer, Beat W

“…Ewing sarcoma is an aggressive cancer with a defective response to DNA damage leading to an enhanced sensitivity to genotoxic agents. Mechanistically, Ewing…”
Get full text

Paracrine Placental Growth Factor Signaling in Response to Ionizing Radiation Is p53-Dependent and Contributes to Radioresistance by Kazimova, Tamara, Tschanz, Fabienne, Sharma, Ashish, Telarovic, Irma, Wachtel, Marco, Pedot, Gloria, Schäfer, Beat, Pruschy, Martin

“…Placental growth factor (PlGF) is a pro-angiogenic, N-glycosylated growth factor, which is secreted under pathologic situations. Here, we investigated the…”
Get full text

RETRACTED: Corrigendum to “Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization” [Neoplasia volume 27 (2022) pp. 100784/Number C] by Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P., Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A., Niggli, Felix K., Schäfer, Beat W.

“…This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/locate/withdrawalpolicy). This article is being…”
Get full text

RETRACTED: Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization by Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P., Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A., Niggli, Felix K., Schäfer, Beat W.

“…This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/locate/withdrawalpolicy). This article is being…”
Get full text

Retraction notice to “Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization” [Neoplasia 27 (2022) 100784] by Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P., Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A., Niggli, Felix K., Schäfer, Beat W.

Get full text

Retraction notice to Corrigendum to “Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization” [Neoplasia 31 (2022) 100805] by Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P., Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A., Niggli, Felix K., Schäfer, Beat W.

Get full text

Abstract B010: The NuRD subunit CHD4 is essential for ewing sarcoma cell survival as it regulates global chromatin architecture by Marques, Joana Graca, Pavlovic, Blaz, Ngo, Quy Ai, Pedot, Gloria, Roemmele, Michaela, Volken, Larissa, Wachtel, Marco, Schäfer, Beat W.

“…Abstract Ewing sarcoma tumorigenesis is tightly linked to epigenetic deregulation. Indeed, the aberrant fusion transcription factor and tumor driver EWS-FLI1…”
Get full text

Enhanced microbial diversity in the saliva microbiome induced by short-term probiotic intake revealed by 16S rRNA sequencing on the IonTorrent PGM platform by Dassi, Erik, Ballarini, Annalisa, Covello, Giuseppina, Quattrone, Alessandro, Jousson, Olivier, De Sanctis, Veronica, Bertorelli, Roberto, Denti, Michela Alessandra, Segata, Nicola

“…•We present here the first IonTorrent PGM profiling of the human saliva microbiome.•The saliva microbiome complexity increases after short-term probiotic…”
Get full text