Search Results - "Pediongco, Troi"
-
1
Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality
Published in Cell reports (Cambridge) (17-09-2019)“…Mucosal-associated invariant T (MAIT) cells are MR1-restricted innate-like T cells conserved across mammalian species, including mice and humans. By sequencing…”
Get full text
Journal Article -
2
MAIT cells contribute to protection against lethal influenza infection in vivo
Published in Nature communications (09-11-2018)“…Mucosal associated invariant T (MAIT) cells are evolutionarily-conserved, innate-like lymphocytes which are abundant in human lungs and can contribute to…”
Get full text
Journal Article -
3
MAIT cells protect against pulmonary Legionella longbeachae infection
Published in Nature communications (22-08-2018)“…Mucosal associated invariant T (MAIT) cells recognise conserved microbial metabolites from riboflavin synthesis. Striking evolutionary conservation and…”
Get full text
Journal Article -
4
Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection
Published in Nature communications (16-07-2021)“…Mucosal-associated Invariant T (MAIT) cells are recognized for their antibacterial functions. The protective capacity of MAIT cells has been demonstrated in…”
Get full text
Journal Article -
5
CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells
Published in The Journal of experimental medicine (05-09-2022)“…Mucosal-associated invariant T (MAIT) cells detect microbial infection via recognition of riboflavin-based antigens presented by the major histocompatibility…”
Get full text
Journal Article -
6
MAIT cell-MR1 reactivity is highly conserved across multiple divergent species
Published in The Journal of biological chemistry (01-06-2024)“…Mucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells that recognize small molecule metabolites presented by major…”
Get full text
Journal Article -
7
Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection
Published in The Journal of immunology (1950) (01-03-2018)“…Mucosal-associated invariant T (MAIT) cells produce inflammatory cytokines and cytotoxic granzymes in response to by-products of microbial riboflavin…”
Get full text
Journal Article -
8
Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo
Published in Frontiers in immunology (31-08-2023)“…Mucosal-associated invariant T (MAIT) cells are a population of innate-like T cells, which mediate host immunity to microbial infection by recognizing…”
Get full text
Journal Article -
9
The balance of interleukin‐12 and interleukin‐23 determines the bias of MAIT1 versus MAIT17 responses during bacterial infection
Published in Immunology and cell biology (01-08-2022)“…Mucosal‐associated invariant T (MAIT) cells are a major subset of innate‐like T cells mediating protection against bacterial infection through recognition of…”
Get full text
Journal Article -
10
RIPK3 controls MAIT cell accumulation during development but not during infection
Published in Cell death & disease (11-02-2023)“…Cell death mechanisms in T lymphocytes vary according to their developmental stage, cell subset and activation status. The cell death control mechanisms of…”
Get full text
Journal Article -
11
Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells
Published in Nature immunology (01-04-2017)“…Mucosal-associated invariant T cells recognize vitamin-B-derived ligands presented via the major-histocompatibility-complex-like molecule MR1. Rossjohn and…”
Get full text
Journal Article -
12
The role of mucosal-associated invariant T cells in visceral leishmaniasis
Published in Frontiers in immunology (15-09-2022)“…Mucosal-associated invariant T (MAIT) cells are restricted by MR1 and are known to protect against bacterial and viral infections. Our understanding of the…”
Get full text
Journal Article