Search Results - "Pediatric pharmacology (New York, N.Y.)"

Effect of cyclophosphamide on oocyte and follicle number in Sprague-Dawley rats, C57BL/6N and DBA/2N mice by Shiromizu, K, Thorgeirsson, S S, Mattison, D R

“…Oocyte and follicle destruction produced by cyclophosphamide was investigated in Sprague-Dawley (SD) rats, and inbred C57BL/6N (B6) and DBA/2N (D2) mice…”
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Can captopril cause fetal and neonatal renal failure? by Rothberg, A D, Lorenz, R

“…We present a case of neonatal renal failure following a pregnancy complicated by hypertension treated with captopril. Clinical investigations showed…”
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Pediatric dosing of acetaminophen by Temple, A R

“…Acetaminophen (paracetamol, APAP) is one of the safest and most widely used analgesic-antipyretics in children. When compared to other analgesic-antipyretics,…”
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Vancomycin pharmacokinetics in premature infants by Gross, J R, Kaplan, S L, Kramer, W G, Mason, Jr, E O

“…Vancomycin pharmacokinetics were studied in nine premature infants. Infants weighing less than 1,000 gm had significantly larger volumes of drug distribution…”
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Gentamicin kinetics in the neonate by Miranda, J C, Schimmel, M M, James, L S, Spinelli, W, Rosen, T S

“…Gentamicin serum levels were measured and elimination half-life was calculated in a group of neonates with postconceptual ages ranging between 25-42 weeks…”
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Optimization of gentamicin therapy in very low birth weight infants by Koren, G, Leeder, S, Harding, E, Jacques, D, MacLeod, S M

“…In order to optimize gentamicin (G) therapy we studied G pharmacokinetics in 48 preterm infants (gest. age 31.6 +/- 3.4, range 25-37 wk; birth weight 1.5 +/-…”
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Pharmacokinetics of intravenous clindamycin in newborn infants by Koren, G, Zarfin, Y, Maresky, D, Spiro, T E, MacLeod, S M

“…We studied 12 newborn infants (gestational ages 26-39 wk [mean +/- SD, 30.6 +/- 4.7]; birth weight 640-2700 g, [mean, 1,322 +/- 688]; postnatal age 1-24 days…”
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Continuous nasogastric administration of activated charcoal for the treatment of theophylline intoxication by Ohning, B L, Reed, M D, Blumer, J L

“…Two adolescents with serum theophylline concentrations in excess of 100 mg/L were treated with continuous nasogastric infusion of activated charcoal after an…”
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The pharmacokinetics of phenytoin in perfused human placenta by Shah, Y G, Miller, R K

“…In vivo phenytoin (PHT) and its metabolites are present in the fetal plasma. In order to determine the transfer kinetics and biotransformation characteristics…”
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Drug-metabolizing enzymes in human foetal liver: partial resolution of multiple cytochromes P 450 by Cresteil, T, Beaune, P, Kremers, P, Flinois, J P, Leroux, J P

“…Cytochrome P 450 concentration, related monooxygenase activities (towards aniline, p-nitroanisole, benzphetamine, ethoxycoumarin, benzo(a)pyrene, testosterone,…”
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Pharmacokinetics of dexamethasone in children by Richter, O, Ern, B, Reinhardt, D, Becker, B

“…A pharmacokinetic data analysis of plasma level data for dexamethasone obtained from children with various diseases and healthy adults was performed. A total…”
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Knowledge of medical students, pediatric residents, and pediatricians about the cost of some medications by Weber, M L, Auger, C, Cléroux, R

“…Medical students, pediatric residents, and pediatricians were asked to evaluate the cost of commonly prescribed medications. Their estimations varied…”
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In-utero gentamicin-induced nephrotoxicity in rats by Mallié, J P, Gerard, H, Gerard, A

“…Aminosides lead to a well-known nephrotoxicity. The possibility of the developing kidney being altered in utero after the pregnant mother's administration has…”
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Assessment of biotransformation during transfer of propoxyphene and acetaminophen across the isolated perfused human placenta by Weigand, U W, Chou, R C, Maulik, D, Levy, G

“…The purpose of this investigation was to assess the extent of biotransformation of drugs by the human placenta during their transfer from the maternal to the…”
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Placental transfer of anticonvulsants (phenobarbital, phenytoin, valproic acid) and the elimination from neonates by Ishizaki, T, Yokochi, K, Chiba, K, Tabuchi, T, Wagatsuma, T

“…In six full-term newborn infants born to epileptic mothers, the cord-to-maternal concentration ratios of anticonvulsants and the plasma disappearance of the…”
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Effects of prostacyclin on the fetal pulmonary circulation by Cassin, S, Winikor, I, Tod, M, Philips, J, Frisinger, J, Jordan, J, Gibbs, C

“…The effects of prostacyclin (PGI2) and its metabolite, 6-keto-PGF1 alpha, on pulmonary and systemic circulations of anesthetized, unventilated fetal goats and…”
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Effects of indomethacin on digoxin pharmacokinetics in preterm infants by Koren, G, Zarfin, Y, Perlman, M, MacLeod, S M

“…Indomethacin is commonly coadministered with digoxin for the treatment of patent ductus arteriosus (PDA) in preterm infants. The combination of digoxin that is…”
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A multicenter comparison of related pharmacologic features of cephalexin and dicloxacillin given for two months to young children with cystic fibrosis by Harrison, C J, Marks, M I, Welch, D F, Sharma, B B, Baker, D, Dice, J

“…Twenty-one cystic fibrosis patients under 3 years of age were enrolled in an open multicenter study to assess the feasibility of the study design and to…”
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Ontogeny of ovarian glutathione and sensitivity to primordial oocyte destruction by cyclophosphamide by Mattison, D R, Shiromizu, K, Pendergrass, J A, Thorgeirsson, S S

“…Ovarian reduced glutathione concentration (microgram/mg wet ovarian weight) develops from levels of less than 0.2 microgram/mg in newborn Osborn Mendel rats to…”
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Pharmacokinetics and metabolism of trimethoprim in neonatal and young pigs by Friis, C, Gyrd-Hansen, N, Nielsen, P, Nordholm, L, Rasmussen, F

“…The pharmacokinetics and metabolism of trimethoprim (TMP) was studied in newborn, 1 and 8-week-old piglets after intravenous administration of 5 mg/kg. Kinetic…”
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