Search Results - "Pediatric pathology & molecular medicine"

Hemostatic Alterations in Sickle Cell Disease: Relationships to Disease Pathophysiology by Stuart, Marie J., Yamaja Setty, B. N.

“…The protean manifestations of sickle cell disease (SCD), especially, microvessel involvement in the vasoocclusive process, is classically ascribed to the…”
Get full text

Localization and Functions of SP-A and SP-D at Mucosal Surfaces by van Rozendaal, Bianca A. W. M., van Golde, Lambert M. G., Haagsman, Henk P.

“…Pulmonary surfactant protein A (SP-A) and D (SP-D), members of the collectin family, are implicated in innate host defense of the lung. Collectins consist of a…”
Get full text

Activation of Vascular Endothelial Cell Adhesion Molecule Expression by Sickle Blood Cells by Brown, Marena D., Wick, Timothy M., Eckman, James R.

“…Microvascular complications in sickle cell disease occur as a result of obstruction of small vessels by deoxygenated sickle cells. Cerebrovascular…”
Get full text

Maintenance of Differentiated Function of the Surfactant System in Human Fetal Lung Type II Epithelial Cells Cultured on Plastic by Gonzales, Linda W., Angampalli, Sree, Guttentag, Susan H., Beers, Mike F., Feinstein, Sheldon I., Matlapudi, Anjaneyulu, Ballard, Philip L.

“…We report a simplified culture system for human fetal lung type II cells that maintains surfactant expression. Type II cells isolated from explant cultures of…”
Get full text

Pulmonary Alveolar Proteinosis: A Review by deMello, Daphne E., Lin, Zhenwu

“…Pulmonary alveolar proteinosis (PAP) is a disorder that rapidly leads to respiratory failure, because the alveolar spaces fill with a lipid-rich, proteinaceous…”
Get full text

Both Human SP-A1 and SP-A2 Genes are Expressed in Small and Large Intestine by Lin, Zhenwu, Demello, Daphne, Phelps, David S., Koltun, Walter A., Page, Michael, Floros, Joanna

“…The human SP-A locus consists of two functional genes and one pseudogene, and SP-A is shown to play a role in local host defense and the regulation of…”
Get full text

Cytogenetic Findings in 36 Osteosarcoma Specimens and a Review of the Literature by Boehm, A. K., Neff, J. R., Squire, J. A., Bayani, J., Nelson, M., Bridge, J. A.

“…Tumor-specific chromosomal abnormalities have been shown to characterize certain subgroups of mesenchymal neoplasms. Identification of these abnormalities has…”
Get full text

Natural history and risk factors of atherosclerosis in children and youth: the PDAY study by Zieske, Arthur W, Malcom, Gray T, Strong, Jack P

“…The Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study was organized to document the natural history of athersclerosis and to determine the…”
Get full text

WILLIAMS SYNDROME ASSOCIATED WITH CROHN DISEASE, MULTIPLE INFECTIONS, AND CHRONIC GRANULOMATOUS DISEASE by Gilbert-Barness, Enid, Fox, Terry, Morrow, Grant, Luquette, Mark, Pomerance, Herbert H.

Get full text

Role of Epistatic (Modifier) Genes in the Modulation of the Phenotypic Diversity of Sickle Cell Anemia by Nagel, Ronald L., Steinberg, Martin H.

“…Sickle hemoglobin is the product of one mutated gene, but the disease phenotype is the product of many genes. Polymorphism among the genes responsible for the…”
Get full text

The role of fibroblast transdifferentiation in lung epithelial cell proliferation, differentiation, and repair in vitro by Torday, J S, Torres, E, Rehan, V K

“…Parathyroid hormone-related protein (PTHrP) expression is necessary for differentiation of mesenchymal lipofibroblasts, which induce epithelial type II (TII)…”
Get more information

HELICOBACTER PYLORI INFECTION IN PEDIATRIC POPULATION: EPIDEMIOLOGY, PATHOPHYSIOLOGY, AND THERAPY by Wallis-Crespo, M. Carolina, Crespo, Antonio

“…Helicobacter pylori, one of the most commonly encountered human pathogens, has been recognized in more than half of adults and children with chronic…”
Get full text

PATHOLOGY TEACH AND TELL: CASTLEMAN DISEASE by Collins, Gary L., Wallis-Crespo, M. Carolina, Gilbert-Barness, Enid

Get full text

The Role of Fine Needle Aspiration Biopsy in the Diagnosis and Management of Osteosarcoma by Kilpatrick, Scott E., Ward, William G., Bos, Gary D., Chauvenet, Allen R., Gold, Stuart H.

“…We retrospectively reviewed our experience with fine needle aspiration biopsy (FNAB) in the diagnosis and management of skeletal osteosarcoma. The…”
Get full text

AN APPROACH TO THE DIAGNOSIS OF METABOLIC DISEASES by Barness, Lewis A.

“…Inborn metabolic errors, which are not common, may have significant implications for patients. Those patients with such errors who have acute life-threatening…”
Get full text

CHARACTERIZATION OF CELLULAR PHENOTYPES AND CYTOKINE EXPRESSION IN BALT FROM CHILDREN WITH CONGENITAL HEART DISEASES by Moussallem, T. M., Guedes, F., Fernandes, E. R., Pagliari, C., Andrade, H. F., Duarte, M. I. S., Lancellotti, C. L. P.

“…The present study was performed to target and call attention to the bronchial associated lymphoid tissue (BALT), part of our immune system, from which, we…”
Get full text

In Situ Hybridization of SP-A mRNA in Adult Human Conducting Airways by Khubchandani, Kavita R., Goss, Kelli L., Engelhardt, John F., Snyder, Jeanne M.

“…In our study, surfactant protein (SP)-A was characterized in adult human trachea and bronchi. SP-A mRNA and protein were localized to serous cells in…”
Get full text

Molecular Pathology and Molecular Pharmacology of Osteosarcoma by Ladanyi, Marc, Gorlick, Richard

“…Abnormalities of many tumor suppressor genes and oncogenes have been described in osteosarcoma, but separating early or primary from secondary or late genetic…”
Get full text

PATHOLOGY TEACH AND TELL: ACROCEPHALOSYNDACTYLY TYPE I (APERT SYNDROME) by Wallis-Crespo, M. Carolina, Gilbert-Barness, Enid

Get full text

CLINICO-PATHOLOGIC CONFERENCE: 17-DAY-OLD GIRL WITH HYPOTHERMIA, DECREASED FEEDINGS, AND LIVER AND KIDNEY FAILURE by Emmanuel, Patricia J., Chamyan, Gabriel, Fisher, John E., Barness, Enid Gilbert, Pomerance, Herbert H.

Get full text