Search Results - "Pedersen, Marianne T."

Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis by Rasmussen, Kasper D, Jia, Guangshuai, Johansen, Jens V, Pedersen, Marianne T, Rapin, Nicolas, Bagger, Frederik O, Porse, Bo T, Bernard, Olivier A, Christensen, Jesper, Helin, Kristian

“…DNA methylation is tightly regulated throughout mammalian development, and altered DNA methylation patterns are a general hallmark of cancer. The…”
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Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids by Sampaziotis, Fotios, Justin, Alexander W, Tysoe, Olivia C, Sawiak, Stephen, Godfrey, Edmund M, Upponi, Sara S, Gieseck, Richard L, de Brito, Miguel Cardoso, Berntsen, Natalie Lie, Gómez-Vázquez, María J, Ortmann, Daniel, Yiangou, Loukia, Ross, Alexander, Bargehr, Johannes, Bertero, Alessandro, Zonneveld, Mariëlle C F, Pedersen, Marianne T, Pawlowski, Matthias, Valestrand, Laura, Madrigal, Pedro, Georgakopoulos, Nikitas, Pirmadjid, Negar, Skeldon, Gregor M, Casey, John, Shu, Wenmiao, Materek, Paulina M, Snijders, Kirsten E, Brown, Stephanie E, Rimland, Casey A, Simonic, Ingrid, Davies, Susan E, Jensen, Kim B, Zilbauer, Matthias, Gelson, William T H, Alexander, Graeme J, Sinha, Sanjay, Hannan, Nicholas R F, Wynn, Thomas A, Karlsen, Tom H, Melum, Espen, Markaki, Athina E, Saeb-Parsy, Kourosh, Vallier, Ludovic

“…Repair of defects in the common bile duct is hampered by a lack of healthy donor tissue. Developing human extrahepatic cholangiocyte organoids and testing them…”
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TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells by Rasmussen, Kasper D, Berest, Ivan, Keβler, Sandra, Nishimura, Koutarou, Simón-Carrasco, Lucía, Vassiliou, George S, Pedersen, Marianne T, Christensen, Jesper, Zaugg, Judith B, Helin, Kristian

“…The epigenetic regulator is frequently mutated in hematological diseases. Mutations have been shown to arise in hematopoietic stem cells early in disease…”
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Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma by Asmar, Fazila, Punj, Vasu, Christensen, Jesper, Pedersen, Marianne T, Pedersen, Anja, Nielsen, Anders B, Hother, Christoffer, Ralfkiaer, Ulrik, Brown, Peter, Ralfkiaer, Elisabeth, Helin, Kristian, Grønbæk, Kirsten

“…The discovery that the Ten-Eleven Translocation (TET) hydroxylases cause DNA demethylation has fundamentally changed the notion of how DNA methylation is…”
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Molecular Regulation of MHC Class I Chain-Related Protein A Expression after HDAC-Inhibitor Treatment of Jurkat T Cells by Andresen, Lars, Jensen, Helle, Pedersen, Marianne T, Hansen, Karen A, Skov, Soren

“…In this study, we characterize the molecular signal pathways that lead to MHC class I chain-related protein A (MICA) expression after histone deacetylase…”
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Tu1266 IMPAIRED VITAMIN D RECEPTOR EXPRESSION AND SIGNALING IN ULCERATIVE COLITIS INTESTINAL EPITHELIAL CELLS by Kellermann, Lauge, Maciag, Grzegorz, Hansen, Stine L., Pedersen, Marianne T., Bergenheim, Fredrik, Riis, Lene, Jensen, Kim, Nielsen, Ole H.

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10: REDUCED COLONIC VITAMIN D RECEPTOR SIGNALING IN FLARING ULCERATIVE COLITIS DUE TO A SPECIFIC LOSS OF CRYPT TOP EPITHELIAL CELLS by Kellermann, Lauge, Bergenheim, Fredrik Olof, Hansen, Stine L., Maciag, Grzegorz, Johansen, Jens Vilstrup, Teves, Joji M., Bressan, Raul B., Baattrup, Astrid M., Pedersen, Marianne T., Riis, Lene, Jensen, Kim, Nielsen, Ole Haagen

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Arimoclomol increases the transcription of lysosomal genes, including NPC1 and NPC2, to facilitate lysosomal function by Petersen, Nikolaj H.T., Klein, Pontus, Valacca, Cristina, Bie, Anne, Magnoni, Raffaella, Pedersen, Marianne T., Lampp, Andrea C., Fog, Cathrine K., Kirkegaard, Thomas T.

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Arimoclomol increases the transcription of lysosomal genes, including and , to facilitate lysosomal function by Petersen, Nikolaj H.T., Klein, Pontus, Valacca, Cristina, Bie, Anne, Magnoni, Raffaella, Pedersen, Marianne T., Lampp, Andrea C., Fog, Cathrine K., Kirkegaard, Thomas T.

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Su1996 - Loading and Tracking Intestinal Organoids with Fluorescent Plga Nanoparticles by Bergenheim, Fredrik H., Seidelin, Jakob B., Pedersen, Marianne T., Yin, Xiaolei, Mead, Benjamin E., Karp, Jeffrey M., Nielsen, Ole H.

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TET Proteins and Histone Modifications in Hematopoiesis by Helin, Kristian, Rasmusssen, Kasper D., Pedersen, Marianne T., Jia, Guangshuai, Williams, Kristine, Johansen, Jens V., Cloos, Paul A.C., Bernard, Olivier A., Christensen, Jesper

“…DNA methylation has been implicated in numerous biological processes including long-term gene silencing, and the development of various diseases, including…”
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DNMT3AR882H mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice by Scourzic, L, Couronné, L, Pedersen, M T, Della Valle, V, Diop, M, Mylonas, E, Calvo, J, Mouly, E, Lopez, C K, Martin, N, Fontenay, M, Bender, A, Guibert, S, Dubreuil, P, Dessen, P, Droin, N, Pflumio, F, Weber, M, Gaulard, P, Helin, K, Mercher, T, Bernard, O A

“…TEN-ELEVEN-TRANSLOCATION-2 ( TET2 ) and DNA-METHYLTRANSFERASE-3A ( DNMT3A ), both encoding proteins involved in regulating DNA methylation, are mutated in…”
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