Search Results - "Pedersen, Mads L."
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Computational phenotyping of brain-behavior dynamics underlying approach-avoidance conflict in major depressive disorder
Published in PLoS computational biology (10-05-2021)“…Adaptive behavior requires balancing approach and avoidance based on the rewarding and aversive consequences of actions. Imbalances in this evaluation are…”
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The Role of the Dorsal–Lateral Prefrontal Cortex in Reward Sensitivity During Approach–Avoidance Conflict
Published in Cerebral cortex (New York, N.Y. 1991) (04-03-2022)“…Abstract Approach–Avoidance conflict (AAC) arises from decisions with embedded positive and negative outcomes, such that approaching leads to reward and…”
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Associations between brain imaging and polygenic scores of mental health and educational attainment in children aged 9–11
Published in NeuroImage (Orlando, Fla.) (01-11-2022)“…Psychiatric disorders are highly heritable and polygenic, and many have their peak onset in late childhood and adolescence, a period of tremendous changes…”
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Associations between everyday activities and arterial spin labeling‐derived cerebral blood flow: A longitudinal study in community‐dwelling elderly volunteers
Published in Human brain mapping (01-06-2023)“…Cerebral blood flow (CBF) is critical for brain metabolism and function. Age‐related changes in CBF are associated with increased risk of neurocognitive…”
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Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults
Published in NeuroImage clinical (01-01-2022)“…•There is an intimate body-brain connection in ageing, and obesity is a key risk factor for poor cardiometabolic health and neurodegenerative conditions.•We…”
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Exploring the associations between physical activity level, cognitive performance, and response to computerized cognitive training among chronic stroke patients
Published in Brain and behavior (01-02-2024)“…Background Post‐stroke attentional and working memory deficits are common and represent relevant predictors of long‐term functional recovery and outcome. The…”
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Increased default-mode variability is related to reduced task-performance and is evident in adults with ADHD
Published in NeuroImage clinical (01-01-2017)“…Insufficient suppression and connectivity of the default mode network (DMN) is a potential mediator of cognitive dysfunctions across various disorders,…”
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Associations between abdominal adipose tissue, reproductive span, and brain characteristics in post-menopausal women
Published in NeuroImage clinical (01-01-2022)“…•Menopause involves decreased oestrogen and higher risk of obesity, which can impact brain health.•Body composition, oestrogen exposure, and brain health…”
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Brain disconnectome mapping derived from white matter lesions and serum neurofilament light levels in multiple sclerosis: A longitudinal multicenter study
Published in NeuroImage clinical (01-01-2022)“…•Individual disconnectome maps generated using a template of 7T MRI data.•Disconnectome maps conceptualize distal brain network aberrations.•Using lesions maps…”
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Modelling ADHD: A review of ADHD theories through their predictions for computational models of decision-making and reinforcement learning
Published in Neuroscience and biobehavioral reviews (01-12-2016)“…•The review analyses core neurobiological theories of ADHD.•Derives their predictions for computational models of decision-making and learning.•Reviews current…”
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Beyond Drift Diffusion Models: Fitting a Broad Class of Decision and Reinforcement Learning Models with HDDM
Published in Journal of cognitive neuroscience (01-09-2022)“…Computational modeling has become a central aspect of research in the cognitive neurosciences. As the field matures, it is increasingly important to move…”
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Cardiometabolic risk factors associated with brain age and accelerate brain ageing
Published in Human brain mapping (01-02-2022)“…The structure and integrity of the ageing brain is interchangeably linked to physical health, and cardiometabolic risk factors (CMRs) are associated with…”
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Simultaneous Hierarchical Bayesian Parameter Estimation for Reinforcement Learning and Drift Diffusion Models: a Tutorial and Links to Neural Data
Published in Computational brain & behavior (01-12-2020)“…Cognitive models have been instrumental for generating insights into the brain processes underlying learning and decision making. In reinforcement learning it…”
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Dissecting the cognitive phenotype of post‐stroke fatigue using computerized assessment and computational modeling of sustained attention
Published in The European journal of neuroscience (01-10-2020)“…Post‐stroke fatigue (PSF) is prevalent among stroke patients, but its mechanisms are poorly understood. Many patients with PSF experience cognitive…”
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A 10-Year Longitudinal Study of Brain Cortical Thickness in People with First-Episode Psychosis Using Normative Models
Published in Schizophrenia bulletin (05-07-2024)“…Clinical forecasting models have potential to optimize treatment and improve outcomes in psychosis, but predicting long-term outcomes is challenging and…”
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Intact responses to non-drug rewards in long-term opioid maintenance treatment
Published in Neuropsychopharmacology (New York, N.Y.) (01-07-2019)“…Disruption of non-drug reward processing in addiction could stem from long-term drug use, addiction-related psychosocial stress, or a combination of these. It…”
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Identifying multimodal signatures underlying the somatic comorbidity of psychosis: the COMMITMENT roadmap
Published in Molecular psychiatry (01-03-2021)Get full text
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Cardiometabolic risk factors associated with brain age and accelerated brain ageing
Published in Human brain mapping (01-02-2022)“…Abstract The structure and integrity of the ageing brain is interchangeably linked to physical health, and cardiometabolic risk factors (CMRs) are associated…”
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Computational Modeling of the n-Back Task in the ABCD Study: Associations of Drift Diffusion Model Parameters to Polygenic Scores of Mental Disorders and Cardiometabolic Diseases
Published in Biological psychiatry : cognitive neuroscience and neuroimaging (01-03-2023)“…Cognitive dysfunction is common in mental disorders and represents a potential risk factor in childhood. The nature and extent of associations between…”
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Assessing the Longitudinal Associations Between Decision-Making Processes and Attention Problems in Early Adolescence
Published in Journal of abnormal child psychology (01-05-2024)“…Cognitive functions and psychopathology develop in parallel in childhood and adolescence, but the temporal dynamics of their associations are poorly…”
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