Search Results - "Pedersen, F"

The Acidic Tumor Microenvironment as a Driver of Cancer by Boedtkjer, Ebbe, Pedersen, Stine F

“…Acidic metabolic waste products accumulate in the tumor microenvironment because of high metabolic activity and insufficient perfusion. In tumors, the acidity…”
Get full text

The SLC9A-C Mammalian Na + /H + Exchanger Family: Molecules, Mechanisms, and Physiology by Pedersen, S F, Counillon, L

“…Na /H exchangers play pivotal roles in the control of cell and tissue pH by mediating the electroneutral exchange of Na and H across cellular membranes. They…”
Get full text

Biophysics and Physiology of the Volume-Regulated Anion Channel (VRAC)/Volume-Sensitive Outwardly Rectifying Anion Channel (VSOR) by Pedersen, Stine F., Okada, Yasunobu, Nilius, Bernd

“…The volume-regulated anion channel (VRAC), also known as the volume-sensitive outwardly rectifying (VSOR) anion channel or the volume-sensitive organic…”
Get full text

Physiology of Cell Volume Regulation in Vertebrates by Hoffmann, Else K, Lambert, Ian H, Pedersen, Stine F

“…Department of Biology, University of Copenhagen, Copenhagen, Denmark The ability to control cell volume is pivotal for cell function. Cell volume perturbation…”
Get full text

Roles of pH in control of cell proliferation by Flinck, M., Kramer, S. H., Pedersen, S. F.

“…Precise spatiotemporal regulation of intracellular pH (pHi) is a prerequisite for normal cell function, and changes in pHi or pericellular pH (pHe) exert…”
Get full text

Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy by Boedtkjer, E, Bunch, L, Pedersen, S F

“…The Na⁺/H⁺-exchanger 1, NHE1 (SLC9A1) and the electroneutral Na⁺,HCO₃⁻ cotransporter NBCn1 (SLC4A7) are coexpressed in a wide range of tissues. Under normal…”
Get more information

TGF-β1 regulates the expression and transcriptional activity of TAZ protein via a Smad3-independent, myocardin-related transcription factor-mediated mechanism by Miranda, Maria Zena, Bialik, Janne Folke, Speight, Pam, Dan, Qinghong, Yeung, Tony, Szászi, Katalin, Pedersen, Stine F., Kapus, András

“…Hippo pathway transcriptional coactivators TAZ and YAP and the TGF-β1 (TGFβ) effector Smad3 regulate a common set of genes, can physically interact, and…”
Get full text

Characterising organic matter in recirculating aquaculture systems with fluorescence EEM spectroscopy by Hambly, A.C., Arvin, E., Pedersen, L.-F., Pedersen, P.B., Seredyńska-Sobecka, B., Stedmon, C.A.

“…The potential of recirculating aquaculture systems (RAS) in the aquaculture industry is increasingly being acknowledged. Along with intensified application,…”
Get full text

Analysis of a power grid using a Kuramoto-like model by Filatrella, G., Nielsen, A. H., Pedersen, N. F.

“… We show that there is a link between the Kuramoto paradigm and another system of synchronized oscillators, namely an electrical power distribution grid of…”
Get full text

Nanoplastics impact the zebrafish (Danio rerio) transcriptome: Associated developmental and neurobehavioral consequences by Pedersen, Adam F., Meyer, Danielle N., Petriv, Anna-Maria V., Soto, Abraham L., Shields, Jeremiah N., Akemann, Camille, Baker, Bridget B., Tsou, Wei-Ling, Zhang, Yongli, Baker, Tracie R.

“…Microplastics (MPs) are a ubiquitous pollutant detected not only in marine and freshwater bodies, but also in tap and bottled water worldwide. While MPs have…”
Get full text

The identification of a volume-regulated anion channel: an amazing Odyssey by Pedersen, S. F., Klausen, T. K., Nilius, B.

“…The volume‐regulated anion channel (VRAC) plays a pivotal role in cell volume regulation in essentially all cell types studied. Additionally, VRAC appears to…”
Get full text

Scaling properties of adsorption energies for hydrogen-containing molecules on transition-metal surfaces by Abild-Pedersen, F, Greeley, J, Studt, F, Rossmeisl, J, Munter, T R, Moses, P G, Skúlason, E, Bligaard, T, Nørskov, J K

“…Density functional theory calculations are presented for CHx, x=0,1,2,3, NHx, x=0,1,2, OHx, x=0,1, and SHx, x=0,1 adsorption on a range of close-packed and…”
Get full text

Operando XAS Study of the Surface Oxidation State on a Monolayer IrOx on RuOx and Ru Oxide Based Nanoparticles for Oxygen Evolution in Acidic Media by Pedersen, Anders F, Escudero-Escribano, Maria, Sebok, Bela, Bodin, Anders, Paoli, Elisa, Frydendal, Rasmus, Friebel, Daniel, Stephens, Ifan E L, Rossmeisl, Jan, Chorkendorff, Ib, Nilsson, Anders

“…Herein we present surface sensitive operando XAS L-edge measurements on IrOx/RuO2 thin films as well as mass-selected RuOx and Ru nanoparticles. We observed…”
Get full text

The Interplay between Dysregulated Ion Transport and Mitochondrial Architecture as a Dangerous Liaison in Cancer by Pedersen, Stine F., Flinck, Mette, Pardo, Luis A.

“…Transport of ions and nutrients is a core mitochondrial function, without which there would be no mitochondrial metabolism and ATP production. Both ion…”
Get full text

Undocumented water column sink for cadmium in open ocean oxygen-deficient zones by Janssen, David J., Conway, Tim M., John, Seth G., Christian, James R., Kramer, Dennis I., Pedersen, Tom F., Cullen, Jay T.

“…Cadmium (Cd) is a micronutrient and a tracer of biological productivity and circulation in the ocean. The correlation between dissolved Cd and the major algal…”
Get full text

Intracellular pH gradients in migrating cells by Martin, Christine, Pedersen, Stine F, Schwab, Albrecht, Stock, Christian

“…Cell polarization along the axis of movement is required for migration. The localization of proteins and regulators of the migratory machinery to either the…”
Get more information

Using the lower limit of normal for the FEV1/FVC ratio reduces the misclassification of airway obstruction by Swanney, M P, Ruppel, G, Enright, P L, Pedersen, O F, Crapo, R O, Miller, M R, Jensen, R L, Falaschetti, E, Schouten, J P, Hankinson, J L, Stocks, J, Quanjer, P H

“…The prevalence of airway obstruction varies widely with the definition used. To study differences in the prevalence of airway obstruction when applying four…”
Get more information

Acoustic Emission-Based Condition Monitoring and Remaining Useful Life Prediction of Hydraulic Cylinder Rod Seals by Pedersen, Jørgen F., Schlanbusch, Rune, Meyer, Thomas J. J., Caspers, Leo W., Shanbhag, Vignesh V.

“…The foremost reason for unscheduled maintenance of hydraulic cylinders in industry is caused by wear of the hydraulic seals. Therefore, condition monitoring…”
Get full text

Regulation and roles of bicarbonate transporters in cancer by Gorbatenko, Andrej, Olesen, Christina W, Boedtkjer, Ebbe, Pedersen, Stine F

“…A unifying feature of solid tumors is a markedly altered pH profile compared to normal tissues. This reflects that solid tumors, despite completely different…”
Get full text

Disrupting Na+,HCO3–-cotransporter NBCn1 (Slc4a7) delays murine breast cancer development by Lee, S, Axelsen, T V, Andersen, A P, Vahl, P, Pedersen, S F, Boedtkjer, E

“…Increased metabolism and insufficient blood supply cause acidic waste product accumulation in solid cancers. During carcinogenesis, cellular acid extrusion is…”
Get full text