Search Results - "Pedersen, Daniel"
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1
Bitopic Ligands and Metastable Binding Sites: Opportunities for G Protein-Coupled Receptor (GPCR) Medicinal Chemistry
Published in Journal of medicinal chemistry (25-05-2017)“…G protein-coupled receptors (GPCRs) belong to a large superfamily of membrane receptors mediating a variety of physiological functions. As such they are…”
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2
Scanning, Contextual Factors, and Association With Performance in English Premier League Footballers: An Investigation Across a Season
Published in Frontiers in psychology (06-10-2020)“…Scanning in football (soccer) denotes an active head movement where a player's face is temporarily directed away from the ball to gather information in…”
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3
Minimal important difference in postoperative morphine consumption after hip and knee arthroplasty using nausea, vomiting, sedation and dizziness as anchors
Published in Acta anaesthesiologica Scandinavica (01-05-2024)“…Morphine-sparing effects are often used to evaluate non-opioid analgesic interventions. The exact effect that would warrant the implementation of these…”
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4
Greening the synthesis of peptide therapeutics: an industrial perspective
Published in RSC advances (24-11-2020)“…Solid-phase peptide synthesis (SPPS) is generally the method of choice for the chemical synthesis of peptides, allowing routine synthesis of virtually any type…”
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Delirium diagnostic tools in the postoperative setting: A scoping review protocol
Published in Acta anaesthesiologica Scandinavica (01-11-2024)“…Background Delirium is an acute and fluctuating disturbance in attention, awareness, and cognition, commonly observed in hospital settings, particularly among…”
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Effect of dexamethasone on intraoperative remifentanil dose in total knee arthroplasty surgery under general anaesthesia
Published in Acta anaesthesiologica Scandinavica (01-10-2022)“…Background The effects of glucocorticoids may include both genomic and rapid nongenomic effects. The potential rapid analgesic effect during surgery has not…”
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‘A tragic destiny overtook him’1: Misunderstanding the Introduction to Schleiermacher's The Christian Faith and his Letters to Lücke
Published in International journal of systematic theology : IJST (01-10-2022)“…In this article I address some important related criticisms of the Introduction to Schleiermacher's The Christian Faith and his Letters to Lücke which have…”
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Associations of dexamethasone's effect on morphine consumption after total knee arthroplasty—Subgroup analyses
Published in Acta anaesthesiologica Scandinavica (01-04-2024)“…The DEXamethasone twice for pain treatment after Total Knee Arthroplasty (DEX‐2‐TKA) trial showed that adding one and two doses of 24 mg intravenous…”
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The PANSAID randomized clinical trial: A pre‐planned 1‐year follow‐up regarding harm
Published in Acta anaesthesiologica Scandinavica (01-08-2020)“…Background Limiting harm from postoperative pain treatment is important. However, long‐term follow‐up from acute pain trials are rare. The aim of the study was…”
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Minimal important difference in opioid consumption based on adverse event reduction—A study protocol
Published in Acta anaesthesiologica Scandinavica (01-02-2023)“…Background The patient‐relevant minimal important difference for opioid consumption remains undetermined, despite its frequent use as primary outcome in trials…”
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Prolonged effects of dexamethasone following total knee arthroplasty: A pre-planned sub-study of the DEX-2-TKA trial
Published in Acta anaesthesiologica Scandinavica (01-01-2024)“…The DEX-2-TKA trial demonstrated that one and two doses of 24 mg intravenous dexamethasone reduced opioid consumption and pain after total knee arthroplasty…”
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12
Electronic Health Lifestyle Coaching Among Diabetes Patients in a Real-Life Municipality Setting: Observational Study
Published in JMIR diabetes (12-03-2019)“…Internet and mobile interventions aiming to promote healthy lifestyle have attracted much attention because of their scalability and accessibility, low costs,…”
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13
Improving neuromuscular monitoring and reducing residual neuromuscular blockade via e‐learning: A multicentre interrupted time‐series study (INVERT study)
Published in Acta anaesthesiologica Scandinavica (01-05-2022)“…Background Neuromuscular monitoring should be applied routinely to avoid residual neuromuscular block. However, anaesthetists often refrain from applying it,…”
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14
Azide- and Alkyne-Derivatised α-Amino Acids
Published in European journal of organic chemistry (01-08-2012)“…With the emergence of the copper‐catalysed Huisgen cycloaddition the use of azide‐ and alkyne‐derivatised α‐amino acids has found widespread use within most…”
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DEX‐2‐TKA—DEXamethasone twice for pain treatment after Total Knee Arthroplasty: A protocol for a randomized, blinded, three‐group multicentre clinical trial
Published in Acta anaesthesiologica Scandinavica (01-02-2020)“…Background Multimodal analgesia is considered the leading principle for post‐operative pain treatment, but no gold standard after total knee arthroplasty (TKA)…”
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16
1,2,3-Triazoles in Peptidomimetic Chemistry
Published in European Journal of Organic Chemistry (01-05-2011)“…The ability to synthesise small peptidomimetics that mimic the secondary structure of proteins is an ever expanding area of research directed at sourcing new…”
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Collaboration for Evidence‐based Practice and Research in Anaesthesia (CEPRA): A consortium initiative for perioperative research
Published in Acta anaesthesiologica Scandinavica (01-07-2023)“…Evidence in perioperative care is insufficient. There is an urgent need for large perioperative research programmes, including pragmatic randomised trials,…”
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DEX‐2‐TKA ‐ DEXamethasone twice for pain treatment after Total Knee Arthroplasty: Detailed statistical analysis plan for a randomized, blinded, three‐group multicentre clinical trial
Published in Acta anaesthesiologica Scandinavica (01-07-2020)“…Background Optimization of post‐operative pain treatment is of upmost importance. Multimodal analgesia is the main post‐operative pain treatment principle, but…”
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Pain treatment after total hip arthroplasty: Detailed statistical analysis plan for the RECIPE randomised clinical trial
Published in Acta anaesthesiologica Scandinavica (01-03-2023)“…Background The RECIPE trial systematically investigates the effects of different combinations of paracetamol, ibuprofen and dexamethasone for pain treatment…”
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Side Chain Cyclized Aromatic Amino Acids: Great Tools as Local Constraints in Peptide and Peptidomimetic Design
Published in Journal of medicinal chemistry (22-12-2016)“…Constraining the conformation of flexible peptides is a proven strategy to increase potency, selectivity, and metabolic stability. The focus has mostly been on…”
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