Search Results - "Peddanna, Kotha"
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Designing, docking and molecular dynamics simulation studies of novel cloperastine analogues as anti-allergic agents: homology modeling and active site prediction for the human histamine H1 receptor
Published in RSC advances (29-01-2020)“…The present study predicts a three-dimensional model for the histamine H1 receptor and the design of antihistamine inhibitors using cloperastine as the core…”
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Exogenous oxygen is required for prostanoid induction under brain ischemia as evidence for a novel regulatory mechanism
Published in Journal of lipid research (01-11-2023)“…Previously, we and others reported a rapid and dramatic increase in brain prostanoids (PG), including prostaglandins, prostacyclins, and thromboxanes, under…”
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Electroacupuncture prevents cocaine-induced conditioned place preference reinstatement and attenuates ΔFosB and GluR2 expression
Published in Scientific reports (01-07-2021)“…Acupuncture has been used for treating drug addiction since the 1970s, but little is known about the mechanisms by which acupuncture affects drug cue-induced…”
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Nephroprotective Effects of Mycophenolate Mofetil and Glibenclamide on Streptozotocin-induced Diabetic Renal Injury in Rats: An Experimental Study
Published in Saudi journal of kidney diseases and transplantation (01-11-2023)“…Diabetic renal injury is a microvascular complication associated with inflammation and oxidative stress, culminating in renal dysfunction. Conventionally, it…”
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Evaluation of biochemical mechanisms of anti-diabetic functions of Anisomeles malabarica
Published in Biomedicine & pharmacotherapy (01-04-2019)“…Anisomeles malabarica (AM) is an aromatic plant traditionally used for the treatment of diabetes mellitus in India. Following bioassay guided fractionation, we…”
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Anti-Diabetic Potential of the Leaves of Anisomeles malabarica in Streptozotocin Induced Diabetic Rats
Published in Cellular physiology and biochemistry (01-01-2017)“…Background/Aims: Diabetes mellitus is a pandemic metabolic disorder that is affecting a majority of populations in recent years. There is a requirement for new…”
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Electroacupuncture improves TBI dysfunction by targeting HDAC overexpression and BDNF-associated Akt/GSK-3β signaling
Published in Frontiers in cellular neuroscience (09-08-2022)“…Background: Acupuncture or electroacupuncture (EA) appears to be a potential treatment in acute clinical traumatic brain injury (TBI); however, it remains…”
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Synthesis, Biological Evaluation, and Molecular Docking Studies of Some Spiro-5-Cyanopyrimidine Derivatives
Published in Russian journal of bioorganic chemistry (01-11-2021)“…A simple, convenient, environmentally benign method has been developed for the synthesis of spiro-5-cyanopyrimidines by multi-component condensation of cyclic…”
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Ceric ammonium nitrate (CAN) catalyzed synthesis and α-glucosidase activity of some novel tetrahydropyridine phosphonate derivatives
Published in Phosphorus, sulfur, and silicon and the related elements (03-08-2019)“…A simple and highly efficient multicomponent one-pot synthesis of a series of pharmaceutically interesting functionalized tetrahydropyridine phosphonate…”
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Analgesic Efficacy of Acupuncture on Chronic Pelvic Pain: A Systemic Review and Meta-Analysis Study
Published in Healthcare (Basel) (01-03-2023)“…Chronic pelvic pain (CPP) is the pain occurred in the pelvic region longer than six months. The monotherapy of medicine may not adequate for the pain…”
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One-pot green synthesis and cytotoxicity of new α-aminophosphonates
Published in Research on chemical intermediates (01-12-2017)“…A novel series of α -aminophosphonates containing the trifluoromethyl aniline moiety were obtained in high yields by condensation of 2-methyl-3-trifluoromethyl…”
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Antihistamine promotes electroacupuncture analgesia in healthy human subjects: A pilot study
Published in Journal of Traditional and Complementary Medicine (01-09-2022)“…Background and aim: We have previously reported that histamine H_1 receptor antagonists facilitate electroacupuncture (EA) analgesia in experimental animals…”
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Understandings of acupuncture application and mechanisms
Published in American journal of translational research (01-01-2022)“…Acupuncture involves the stimulation of acupoints, which are located at specific sites of the human body, by insertion of fine metal needles, followed by…”
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One-pot synthesis of thiazolo[3,2-a]pyrimidine derivatives, their cytotoxic evaluation and molecular docking studies
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (15-04-2020)“…An economical, simple and efficient one-pot method has been developed for the synthesis of thiazolo[3,2-a]pyrimidine hydrobromide derivatives…”
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Efficacy of Cyanotis tuberosa (Roxb.) Schult. &Schult. f. root tubers' active fraction as anti-diabetic, antihyperlipidemic and antioxidant in Streptozotocin-induced diabetic rats
Published in Journal of ethnopharmacology (01-03-2022)“…Cyanotis tuberosa (Roxb.) Schult. &Schult.f. is traditionally used as ethnomedicine for curing several ailments like diabetes, liver problems, ulcers, etc. The…”
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Antidiabetic activity of root tubers of Asparagus gonoclados Baker in streptozotocin induced diabetic rats
Published in Journal of ethnopharmacology (05-10-2019)“…Asparagus gonoclados Baker is a traditional folk remedy used for diabetes, diuretic, galactogogue, gastric ulcer activities etc. The present investigation was…”
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Antihyperglycemic Activity of Asparagus gonoclados Root Tubers in Streptozotocininduced Diabetic Rats
Published in The FASEB journal (01-04-2018)“…Diabetes mellitus is the most common metabolic disorder affecting more than 422 million people worldwide. The available pharmacological approaches for the…”
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Antidiabetic Activity of Root Tubers of Cyanotis tuberosa in Streptozotocin Induced Diabetic Rats
Published in The FASEB journal (01-04-2019)“…Diabetes mellitus arising due to insufficient insulin production or its action or both is characterized by hyperglycemia. According to WHO it ranks as the…”
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12-Hydroxyeicosatetraenoic acid is the only enzymatically produced HETE increased under brain ischemia
Published in Prostaglandins, leukotrienes and essential fatty acids (01-03-2024)“…•12-HETE is the only enzymatically produced HETE in the ischemic brain as demonstrated by chiral chromatography-mass spectrometry analysis.•Other HETE are…”
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