Search Results - "Pedapati, Jyothi"

Inclusion of a portion of the native SNCA 3′UTR reduces toxicity of human S129A SNCA on striatal‐projecting dopamine neurons in rat substantia Nigra by Khodr, Christina E., Pedapati, Jyothi, Han, Ye, Bohn, Martha C.

“…Experimental models of Parkinson's disease (PD) created by aberrant expression of the alpha‐synuclein (SNCA) coding region have been reported. However,…”
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A microRNA embedded AAV alpha-synuclein gene silencing vector for dopaminergic neurons by Han, Ye, Khodr, Christina E, Sapru, Mohan K, Pedapati, Jyothi, Bohn, Martha C

“…Abstract Alpha-synuclein (SNCA), an abundantly expressed presynaptic protein, is implicated in Parkinson's disease (PD). Since over-expression of human SNCA…”
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Inclusion of a portion of the native SNCA 3'UTR reduces toxicity of human S129A SNCA on striatal-projecting dopamine neurons in rat substantia nigra by Khodr, Christina E, Pedapati, Jyothi, Han, Ye, Bohn, Martha C

“…Experimental models of Parkinson's disease (PD) created by aberrant expression of the alpha-synuclein (SNCA) coding region have been reported. However,…”
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An alpha-synuclein AAV gene silencing vector ameliorates a behavioral deficit in a rat model of Parkinson's disease, but displays toxicity in dopamine neurons by Khodr, Christina E, Sapru, Mohan K, Pedapati, Jyothi, Han, Ye, West, Neva C, Kells, Adrian P, Bankiewicz, Krystof S, Bohn, Martha C

“…Abstract Effects of silencing ectopically expressed hSNCA in rat substantia nigra (SN) were examined as a novel therapeutic approach to Parkinson's disease…”
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