Search Results - "Peck, Konan"
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Selection of aptamers targeting the sialic acid receptor of hemagglutinin by epitope-specific SELEX
Published in Chemical communications (Cambridge, England) (14-08-2014)“…A new SELEX scheme is proposed for the selection of aptamers targeting a specific epitope of a native protein. Anti-sialic acid receptor (SAR) aptamers that…”
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2
A new nucleic acid–based agent inhibits cytotoxic T lymphocyte–mediated immune disorders
Published in Journal of allergy and clinical immunology (01-09-2013)“…Background Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and graft-versus-host disease (GVHD) are distinct immune reactions elicited by…”
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3
Early Assessment of Colorectal Cancer by Quantifying Circulating Tumor Cells in Peripheral Blood: ECT2 in Diagnosis of Colorectal Cancer
Published in International journal of molecular sciences (01-04-2017)“…Circulating tumor cells (CTCs) in peripheral blood is an indication of poor prognosis for patients with different cancer types. However, most of the available…”
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Prognosis of Non–Small Cell Lung Cancer Patients by Detecting Circulating Cancer Cells in the Peripheral Blood with Multiple Marker Genes
Published in Clinical cancer research (01-01-2005)“…Purpose: Current lung cancer staging and prognosis methods are based on imaging methods, which may not be sensitive enough for early and accurate detection of…”
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Human kallikrein 8 protease confers a favorable clinical outcome in non-small cell lung cancer by suppressing tumor cell invasiveness
Published in Cancer research (Chicago, Ill.) (15-12-2006)“…The human kallikrein 8 (KLK8) gene, a member of the human tissue kallikrein gene family, encodes a serine protease. The KLK8 protein (hK8) is known to be a…”
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Design of microarray probes for virus identification and detection of emerging viruses at the genus level
Published in BMC bioinformatics (28-04-2006)“…Most virus detection methods are geared towards the detection of specific single viruses or just a few known targets, and lack the capability to uncover the…”
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Overcoming EGFR T790M-based Tyrosine Kinase Inhibitor Resistance with an Allele-specific DNAzyme
Published in Molecular therapy. Nucleic acids (01-03-2014)“…Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are the main therapeutic agents used to treat non–small-cell lung cancer patients…”
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Acid-Induced Gene Expression in Helicobacter pylori: Study in Genomic Scale by Microarray
Published in Infection and Immunity (01-03-2001)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A multivariate prediction model for microarray cross-hybridization
Published in BMC bioinformatics (01-03-2006)“…Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the…”
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10
Matching Gene Activity with Physiological Functions
Published in Proceedings of the National Academy of Sciences - PNAS (05-03-2002)“…Matching the activity of the genes with biomechanics and physiology is an effective way to use cDNA microarray technology. Required are data on the change of…”
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AptBCis1, An Aptamer–Cisplatin Conjugate, Is Effective in Lung Cancer Leptomeningeal Carcinomatosis
Published in ACS nano (15-10-2024)“…Treatment of lung cancer leptomeningeal carcinomatosis (LM) remains challenging partly due to the biological nature of the blood–brain barrier (BBB). Cisplatin…”
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12
Genomic analysis of smooth muscle cells in three‐dimensional collagen matrix
Published in The FASEB journal (01-01-2003)“…ABSTRACT The proliferation, differentiation, and protein synthesis of vascular smooth muscle cells (SMCs) play important roles in vascular remodeling. Here, we…”
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13
Optimization of high-sensitivity fluorescence detection
Published in Analytical chemistry (Washington) (01-09-1990)“…We present general expressions for the number of photons emitted by a fluorescent chromophore as a function of the intensity and the duration of illumination…”
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14
Enhancement of Aptamer Microarray Sensitivity through Spacer Optimization and Avidity Effect
Published in Analytical chemistry (Washington) (01-03-2009)“…This work aims for ultrasensitive detection of target proteins in complex biological matrixes based on aptamer microarrays. Two extensively studied aptamers…”
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Synergistic inhibition of lung cancer cell invasion, tumor growth and angiogenesis using aptamer-siRNA chimeras
Published in Biomaterials (01-03-2014)“…Abstract Early metastasis is one of the major causes of mortality among patient with lung cancer. The process of tumor metastasis involves a cascade of events,…”
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Signal-on Protein Detection via Dye Translocation between Aptamer and Quantum Dot
Published in ACS applied materials & interfaces (18-05-2016)“…A unique interaction between the cyanine dye and negatively charged quantum dot is used to construct a signal-on biaptameric quantum dot (QD) Förster…”
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Aptamer microarray as a novel bioassay for protein–protein interaction discovery and analysis
Published in Biosensors & bioelectronics (15-04-2013)“…Aptamer microarray is investigated as a novel bioassay for protein–protein interaction (PPI) discovery and analysis. Assaying a mixture of fluorescence-labeled…”
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SCUBE3 regulation of early lung cancer angiogenesis and metastatic progression
Published in Clinical & experimental metastasis (01-08-2013)“…Signal peptide-CUB-EGF-like domain-containing protein 3 (SCUBE3) is strongly expressed in extremely invasive lung carcinoma. We showed in our previous study…”
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Aptamer Sequence Deconvolution through Microarray Technology
Published in Biophysical journal (27-01-2015)Get full text
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20
Identification and characterization of oligonucleotides that inhibit Toll‐like receptor 2‐associated immune responses
Published in The FASEB journal (01-09-2009)“…ABSTRACT Toll‐like receptors (TLRs) play important roles in the immune responses against invading microorganisms. Development of TLR antagonists is recognized…”
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