Search Results - "Peat, Tyler"

The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription by Malik, Navdeep, Yan, Hualong, Moshkovich, Nellie, Palangat, Murali, Yang, Howard, Sanchez, Vanesa, Cai, Zhuo, Peat, Tyler J., Jiang, Shunlin, Liu, Chengyu, Lee, Maxwell, Mock, Beverly A., Yuspa, Stuart H., Larson, Daniel, Wakefield, Lalage M., Huang, Jing

“…Translation and transcription are frequently dysregulated in cancer. These two processes are generally regulated by distinct sets of factors. The CBFB gene,…”
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Efficacy, Tolerability, and Pharmacokinetics of Combined Targeted MEK and Dual mTORC1/2 Inhibition in a Preclinical Model of Mucosal Melanoma by Wei, Bih-Rong, Hoover, Shelley B, Peer, Cody J, Dwyer, Jennifer E, Adissu, Hibret A, Shankarappa, Priya, Yang, Howard, Lee, Maxwell, Peat, Tyler J, Figg, William D, Simpson, R Mark

“…Melanomas arising in the mucous membranes are a rare and aggressive subtype. New treatment approaches are needed, yet accumulating sufficient evidence to…”
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Fatty acid oxidation is required for embryonic stem cell survival during metabolic stress by Yan, Hualong, Malik, Navdeep, Kim, Young-Im, He, Yunlong, Li, Mangmang, Dubois, Wendy, Liu, Huaitian, Peat, Tyler J, Nguyen, Joe T, Tseng, Yu-Chou, Ayaz, Gamze, Alzamzami, Waseem, Chan, King, Andresson, Thorkell, Tessarollo, Lino, Mock, Beverly A, Lee, Maxwell P, Huang, Jing

“…Metabolic regulation is critical for the maintenance of pluripotency and the survival of embryonic stem cells (ESCs). The transcription factor Tfcp2l1 has…”
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Pathology in Practice by Peat, Tyler J, Miller, Margaret A

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Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma by Peat, Tyler J., Gaikwad, Snehal M., Dubois, Wendy, Gyabaah-Kessie, Nana, Zhang, Shuling, Gorjifard, Sayeh, Phyo, Zaw, Andres, Megan, Hughitt, V. Keith, Simpson, R. Mark, Miller, Margaret A., Girvin, Andrew T., Taylor, Andrew, Williams, Daniel, D'Antonio, Nelson, Zhang, Yong, Rajagopalan, Adhithi, Flietner, Evan, Wilson, Kelli, Zhang, Xiaohu, Shinn, Paul, Klumpp-Thomas, Carleen, McKnight, Crystal, Itkin, Zina, Chen, Lu, Kazandijian, Dickran, Zhang, Jing, Michalowski, Aleksandra M., Simmons, John K., Keats, Jonathan, Thomas, Craig J., Mock, Beverly A.

“…Drug resistance and disease progression are common in multiple myeloma (MM) patients, underscoring the need for new therapeutic combinations. A high-throughput…”
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Improving science-based invasive species management with physiological knowledge, concepts, and tools by Lennox, Robert, Choi, Kevin, Harrison, Philip M, Paterson, James E, Peat, Tyler B, Ward, Taylor D, Cooke, Steven J

“…Biological invasions are a prominent factor contributing to global biodiversity loss. As a result, managing invasive species is a priority for many…”
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Hypomorphic mTOR Downregulates CDK6 and Delays Thymic Pre-T LBL Tumorigenesis by Gary, Joy M., Simmons, John K., Xu, Jinfei, Zhang, Shuling, Peat, Tyler J., Watson, Nicholas, Gamache, Benjamin J., Zhang, Ke, Kovalchuk, Alexander L., Michalowski, Aleksandra M., Chen, Jin-Qiu, Thaiwong, Tuddow, Kiupel, Matti, Gaikwad, Snehal, Etienne, Maudeline, Simpson, R. Mark, Dubois, Wendy, Testa, Joseph R., Mock, Beverly A.

“…PI3K/AKT/mTOR pathway hyperactivation is frequent in T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LBL). To model inhibition of mTOR, pre–T-cell…”
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Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression by Chen, Jichun, Zhang, Shuling, Feng, Xingmin, Wu, Zhijie, Dubois, Wendy, Thovarai, Vishal, Ahluwalia, Sonia, Gao, Shouguo, Chen, Jinguo, Peat, Tyler, Sen, Shurjo K, Trinchieri, Giorgio, Young, Neal S, Mock, Beverly A

“…Specific-pathogen-free (SPF) mice have improved hematopoietic characteristics relative to germ-free mice, however, it is not clear whether improvements in…”
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Pax8, Napsin A, and CD10 as Immunohistochemical Markers of Canine Renal Cell Carcinoma by Peat, Tyler J., Edmondson, Elijah F., Miller, Margaret A., DuSold, Dee M., Ramos-Vara, José A.

“…Pax8, napsin A, and CD10 are useful immunohistochemical markers of human renal cell carcinoma (RCC); however, their diagnostic utility in canine RCC is…”
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Dose-Related Induction of Hepatic Preneoplastic Lesions by Diethylnitrosamine in C57BL/6 Mice by Kushida, Masahiko, Kamendulis, Lisa M., Peat, Tyler J., Klaunig, James E.

“…The C57BL/6 mouse strain (or derivation of this strain) is used as a background for many transgenic mouse models. This strain has a relatively low…”
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Characteristic lipid profiles of canine non-Hodgkin's lymphoma from surgical biopsy tissue sections and fine needle aspirate smears by desorption electrospray ionization--mass spectrometry by Jarmusch, Alan K, Kerian, Kevin S, Pirro, Valentina, Peat, Tyler, Thompson, Craig A, Ramos-Vara, José A, Childress, Michael O, Cooks, R Graham

“…Canine non-Hodgkin's lymphoma (NHL) is a heterogeneous group of cancers representing approximately 15% of all canine cancers. Further, canine NHL mimics human…”
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Seasonal thermal ecology of adult walleye (Sander vitreus) in Lake Huron and Lake Erie by Peat, Tyler B., Hayden, Todd A., Gutowsky, Lee F.G., Vandergoot, Christopher S., Fielder, David G., Madenjian, Charles P., Murchie, Karen J., Dettmers, John M., Krueger, Charles C., Cooke, Steven J.

“…The purpose of this study was to characterize thermal patterns and generate occupancy models for adult walleye from lakes Erie and Huron with internally…”
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A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco‐associated cancers, lung and bladder cancer, by targeting NF‐κB and generating reactive oxygen species by Shanmugam, Rajasubramaniam, Kusumanchi, Praveen, Appaiah, Hitesh, Cheng, Liang, Crooks, Peter, Neelakantan, Sundar, Peat, Tyler, Klaunig, James, Matthews, William, Nakshatri, Harikrishna, Sweeney, Christopher J.

“…Dimethylaminoparthenolide (DMAPT) is a water soluble parthenolide analog with preclinical activity in hematologic malignancies. Using non–small lung cancer…”
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Cooperative Drug Combinations Target Oncogenes and Tumor Suppressors in Cancer by Peat, Tyler J

“…Multiple myeloma (MM)is a neoplasm involving plasma cells in the bone marrow. Drug resistance and progression are common, underscoring the need for new drug…”
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Cover Image, Volume 59, Issue 2 by Li, Jun, Dubois, Wendy, Thovarai, Vishal, Wu, Zhijie, Feng, Xingmin, Peat, Tyler, Zhang, Shuling, Sen, Shurjo K., Trinchieri, Giorgio, Chen, Jichun, Mock, Beverly A., Young, Neal S.

“…The cover image is based on the Original Article Atienuation of immune‐mediated bone marrow damage in conventionally‐housed mice by Beverly Mock, Tyler Peat,…”
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Attenuation of immune‐mediated bone marrow damage in conventionally housed mice by Li, Jun, Dubois, Wendy, Thovarai, Vishal, Wu, Zhijie, Feng, Xingmin, Peat, Tyler, Zhang, Shuling, Sen, Shurjo K., Trinchieri, Giorgio, Chen, Jichun, Mock, Beverly A., Young, Neal S.

“…In humans, bone marrow (BM) failure syndromes, both constitutional and acquired, predispose to myeloid malignancies. We have modeled acquired immune aplastic…”
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