Search Results - "Pearson, T.C."

Fc‐Silent Anti‐CD154 Domain Antibody Effectively Prevents Nonhuman Primate Renal Allograft Rejection by Kim, S. C., Wakwe, W., Higginbotham, L. B., Mathews, D. V., Breeden, C. P., Stephenson, A. C., Jenkins, J., Strobert, E., Price, K., Price, L., Kuhn, R., Wang, H., Yamniuk, A., Suchard, S., Farris, A. B., Pearson, T. C., Larsen, C. P., Ford, M. L., Suri, A., Nadler, S., Adams, A. B.

“…The advent of costimulation blockade provides the prospect for targeted therapy with improved graft survival in transplant patients. Perhaps the most effective…”
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Detection of contaminated hazelnuts and ground red chili pepper flakes by multispectral imaging by Kalkan, H., Beriat, P., Yardimci, Y., Pearson, T.C.

“…► Aflatoxin contaminated food items can be detected by multispectral imaging. ► Aflatoxin level of the food lot can be decreased by elimination of the detected…”
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Donor‐Directed MHC Class I Antibody Is Preferentially Cleared from Sensitized Recipients of Combined Liver/Kidney Transplants by Dar, W., Agarwal, A., Watkins, C., Gebel, H. M., Bray, R. A., Kokko, K. E., Pearson, T. C., Knechtle, S. J.

“…For patients with chronic renal and liver diseases, simultaneous liver and kidney transplantation (SLKT) is the best therapeutic option. The role of a…”
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CTLA4Ig Prevents Alloantibody Formation Following Nonhuman Primate Islet Transplantation Using the CD40‐Specific Antibody 3A8 by Badell, I. R., Russell, M. C., Cardona, K., Shaffer, V. O., Turner, A. P., Avila, J. G., Cano, J. A., Leopardi, F. V., Song, M., Strobert, E. A., Ford, M. L., Pearson, T. C., Kirk, A. D., Larsen, C. P.

“…Islet transplantation to treat type 1 diabetes has been limited in part by toxicities of current immunosuppression and recipient humoral sensitization…”
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Transplant Tolerance in Non‐Human Primates: Progress, Current Challenges and Unmet Needs by Kean, L. S., Gangappa, S., Pearson, T. C., Larsen, C. P.

“…Given the significant morbidity associated with current post‐transplant immunosuppressive regimens, induction of immune tolerance continues to be an important…”
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NK Cells Rapidly Reject Allogeneic Bone Marrow in the Spleen Through a Perforin‐ and Ly49D‐Dependent, but NKG2D‐Independent Mechanism by Hamby, K., Trexler, A., Pearson, T. C., Larsen, C. P., Rigby, M. R., Kean, L. S.

“…We have used a sensitive and specific in vivo killing assay to monitor the kinetics, anatomic location and mechanisms controlling NK‐mediated rejection of…”
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Expanded Nonhuman Primate Tregs Exhibit a Unique Gene Expression Signature and Potently Downregulate Alloimmune Responses by Anderson, A., Martens, C. L., Hendrix, R., Stempora, L. L., Miller, W. P., Hamby, K., Russell, M., Strobert, E., Blazar, B. R., Pearson, T. C., Larsen, C. P., Kean, L. S.

“…We have established two complementary strategies for purifying naturally occurring regulatory T cells (Tregs) from rhesus macaques in quantities that would be…”
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Surgical Complications in 275 Human Immunodeficiency Virus (HIV) Infected Liver and/or Kidney Transplant Recipients by Harbell, J, Nissen, N, Olthoff, K, Florman, S.S, Hanto, D.W, Light, J, Bartlett, S.T, Tzakis, A.G, Pearson, T.C, Barin, B, Fung, J, Stock, P.G

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Spectral Properties and Effect of Drying Temperature on Almonds with Concealed Damage by Pearson, T.C.

“…The feasibility of using near infrared light transmission, obtained after drying, to predict if an almond would develop concealed damage after roasting was…”
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Belatacept Combined With Transient Calcineurin Inhibitor Therapy Prevents Rejection and Promotes Improved Long‐Term Renal Allograft Function by Adams, A. B., Goldstein, J., Garrett, C., Zhang, R., Patzer, R. E., Newell, K. A., Turgeon, N. A., Chami, A. S., Guasch, A., Kirk, A. D., Pastan, S. O., Pearson, T. C., Larsen, C. P.

“…Belatacept, a T cell costimulation blocker, demonstrated superior renal function, lower cardiovascular risk, and improved graft and patient survival in renal…”
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Engraftment of Adult Porcine Islet Xenografts in Diabetic Nonhuman Primates Through Targeting of Costimulation Pathways by Cardona, K., Milas, Z., Strobert, E., Cano, J., Jiang, W., Safley, S.A, Gangappa, S., Hering, B.J, Weber, C.J, Pearson, T.C, Larsen, C.P

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Renal Transplantation Using Belatacept Without Maintenance Steroids or Calcineurin Inhibitors by Kirk, A. D., Guasch, A., Xu, H., Cheeseman, J., Mead, S. I., Ghali, A., Mehta, A. K., Wu, D., Gebel, H., Bray, R., Horan, J., Kean, L. S., Larsen, C. P., Pearson, T. C.

“…Kidney transplantation remains limited by toxicities of calcineurin inhibitors (CNIs) and steroids. Belatacept is a less toxic CNI alternative, but existing…”
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Experience with a Novel Efalizumab‐Based Immunosuppressive Regimen to Facilitate Single Donor Islet Cell Transplantation by Turgeon, N. A., Avila, J. G., Cano, J. A., Hutchinson, J. J., Badell, I. R., Page, A. J., Adams, A. B., Sears, M. H., Bowen, P. H., Kirk, A. D., Pearson, T. C., Larsen, C. P.

“…Islet transplantation is an experimental therapy for selected patients with type 1 diabetes (T1DM). It remains limited by immunosuppressive drug toxicity,…”
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Development of a calibration to predict maize seed composition using single kernel near infrared spectroscopy by Baye, Tesfaye M., Pearson, Tom C., Settles, A. Mark

“…The relative composition of protein, oil, and starch in the maize kernel has a large genetic component. Predictions of kernel composition based on…”
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Racial Disparities in Kidney Graft Survival: Does Donor Quality Explain the Difference? by Patzer, R. E., Pearson, T. C.

“…Deceased donor kidney quality explains little of the racial differences in allograft survival, and opportunities remain to address racial disparities in kidney…”
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Organ Donation and Utilization, 1995–2004: Entering the Collaborative Era by Marks, W. H., Wagner, D., Pearson, T. C., Orlowski, J. P., Nelson, P. W., McGowan, J. J., Guidinger, M. K., Burdick, J.

“…Continued progress in organ donation will help enable transplantation to alleviate the increasing incidence of end‐stage organ disease. This article discusses…”
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Miles to Go by Kirk, A. D., Knechtle, S. J., Larsen, C. P., Newell, K. A., Pearson, T. C.

“…The authors outline ways in which transplant research will need to reinvent itself to address the root causes of late allograft loss. See article by Lodhi et…”
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NK Cells Mediate Costimulation Blockade‐Resistant Rejection of Allogeneic Stem Cells During Nonmyeloablative Transplantation by Kean, L. S., Hamby, K., Koehn, B., Lee, E., Coley, S., Stempora, L., Adams, A. B., Heiss, E., Pearson, T. C., Larsen, C. P.

“…Although T‐cell CD28/CD40 costimulation blockade represents a powerful mechanism to promote immune tolerance during murine allotransplantation, it has not yet…”
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Reduction of aflatoxin and fumonisin contamination in yellow corn by high-speed dual-wavelength sorting by Pearson, T.C, Wicklow, D.T, Pasikatan, M.C

“…A high-speed dual-wavelength sorter was tested for removing corn contaminated in the field with aflatoxin and fumonisin. To achieve accurate sorting, single…”
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Hyperhemolytic transfusion reaction in sickle cell disease by Win, Nay, Doughty, Heidi, Telfer, Paul, Wild, Barbara J., Pearson, T.C.

“…BACKGROUND: An atypical form of life‐threatening hemolytic transfusion reaction (HTR) in patients with sickle cell disease (SCD) has been well described in the…”
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