Search Results - "Pearson, S.‐A."

What proportion of patients with chronic noncancer pain are prescribed an opioid medicine? Systematic review and meta‐regression of observational studies by Mathieson, S., Wertheimer, G., Maher, C.G., Christine Lin, C.‐W., McLachlan, A.J., Buchbinder, R., Pearson, S.‐A., Underwood, M.

“…Guidelines now discourage opioid analgesics for chronic noncancer pain because the benefits frequently do not outweigh the harms. We aimed to determine the…”
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Too much or not enough? A comment on discrepancies in published estimates of opioid use in Australia by Karanges, E. A., Pearson, S.-A.

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De novo and recurrent metastatic breast cancer – A systematic review of population-level changes in survival since 1995 by Lord, SJ, Bahlmann, K, O'Connell, DL, Kiely, BE, Daniels, B, Pearson, SA, Beith, J, Bulsara, MK, Houssami, N

“…Advances in breast cancer (BC) care have reduced mortality, but their impact on survival once diagnosed with metastasis is less well described. This systematic…”
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Positive spillover effects of prescribing requirements: increased cardiac testing in patients treated with trastuzumab for HER2+ metastatic breast cancer by Lu, C. Y., Srasuebkul, P., Drew, A. K., Ward, R. L., Pearson, S.-A.

“…Background Cardiotoxicity is a concern in patients on trastuzumab therapy, and cardiac function assessment is a recommended practice. In 2006, trastuzumab was…”
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Implementing a web-based oncology protocol system in Australia: evaluation of the first 3 years of operation by Hains, I. M., Ward, R. L., Pearson, S.-A.

“…Background:  EviQ is a web‐based oncology protocol system launched across Australia in 2005 (http://www.eviq.org.au). We evaluated eviQ use at the…”
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Demographic, social and lifestyle risk factors for cancer registry-notified cancer of unknown primary site (CUP) by Vajdic, C.M., Perez-Concha, O., Dobbins, T., Ward, R.L., Schaffer, A.L., van Leeuwen, M.T., Rhee, J.J., Laaksonen, M.A., Craigen, G., Pearson, S.A.

“…•Older age and smoking increase risk of CUP independent of overall health.•Novel association between low educational attainment and increased risk of CUP.•No…”
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Governance approval for multisite, non-interventional research: what can Harmonisation of Multi-Centre Ethical Review learn from the New South Wales experience? by Vajdic, C. M., Meagher, N. S., Hicks, S. C., Faedo, M., Ward, R. L., Pearson, S.-A.

“…Background:  In 2007, New South Wales Health mandated the separation of ethical and scientific review from research governance at all New South Wales public…”
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Health-related predictors of cancer registry-notified cancer of unknown primary site (CUP) by Vajdic, C.M., Perez-Concha, O., Rhee, J.J., Dobbins, T., Ward, R.L., Schaffer, A.L., van Leeuwen, M.T., Laaksonen, M.A., Craigen, G., Pearson, S.A.

“…•A large prospective cohort with linked administrative health records.•The risk of CUP was increased in people with poor self-rated overall health.•CUP risk…”
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The quality of web-based oncology guidelines and protocols: how do international sites stack up? by Langton, J M, Drew, A K, Mellish, L, Olivier, J, Ward, R L, Pearson, S-A

“…Background: The Internet is a popular medium for disseminating information relevant to oncology practitioners. Despite the widespread use of web-based…”
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Graduate entry to medical school? Testing some assumptions by Rolfe, I E, Ringland, C, Pearson, S‐A

“…Background  Debate abounds regarding the most appropriate candidates to admit to medical school. This paper examines whether there is any advantage to…”
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Information sources used by New South Wales cancer clinicians: a qualitative study by Tan, E. L., Stark, H., Lowinger, J. S., Ringland, C., Ward, R., Pearson, S.-A.

“…Background: This study identified (i) information sources used by cancer clinicians to guide pharmacological treatments, (ii) utilization of, and opinions…”
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Patterns of analgesic and anti-inflammatory medicine use by Australian veterans by Pearson, S.-A., Ringland, C., Kelman, C., Mant, A., Lowinger, J., Stark, H., Nichol, G., Day, R., Henry, D.

“…Background: We examined analgesic and anti‐inflammatory medicine use by Australian veterans before and after the introduction of selective Cox‐2 inhibitors…”
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Serious Offenders: Using Evidence to Predict and Manage the Risk by Pearson, Dominic A.S., McDougall, Cynthia

“…In response to the risk of serious further offences, an evidence‐based approach is needed in risk management. A recent joint prison–probation inspection of the…”
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A binary adenoviral vector system for expressing high levels of the proapoptotic gene bax by KAGAWA, S, PEARSON, S. A, JI, L, XU, K, MCDONNELL, T. J, SWISHER, S. G, ROTH, J. A, FANG, B

“…The bax gene plays a critical role in signaling apoptosis and expression through gene transfer may be valuable in the treatment of a variety of…”
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Graduate entry to medical school? Testing some assumptions by Rolfe, I E, Ringland, C, Pearson, S-A

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Disinvestment and Value-Based Purchasing Strategies for Pharmaceuticals: An International Review by Parkinson, Bonny, Sermet, Catherine, Clement, Fiona, Crausaz, Steffan, Godman, Brian, Garner, Sarah, Choudhury, Moni, Pearson, Sallie-Anne, Viney, Rosalie, Lopert, Ruth, Elshaug, Adam G.

“…Pharmaceutical expenditure has increased rapidly across many Organisation for Economic Cooperation and Development (OECD) countries over the past three…”
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Factors Limiting Adenovirus-mediated Gene Transfer into Human Lung and Pancreatic Cancer Cell Lines by Pearson, A S, Koch, P E, Atkinson, N, Xiong, M, Finberg, R W, Roth, J A, Fang, B

“…Adenoviral vectors are a widely used means of gene transfer. However, transgene expression after adenoviral administration varies among different carcinoma…”
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The detection of telomerase activity in patients with adenocarcinoma of the pancreas by fine needle aspiration by Pearson, A S, Chiao, P, Zhang, L, Zhang, W, Larry, L, Katz, R L, Evans, D B, Abbruzzese, J L

“…Telomerase activation in differentiated cells is associated with cell immortalization. Detection of telomerase expression in cancer provides a potential…”
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Which common clinical conditions should medical students be able to manage by graduation? A perspective from Australian interns by Rolfe, I.E., Pearson, S.-A., Sanson-Fisher, R.W., Ringland, C., Bayley, S., Hart, A., Kelly, S.

“…The objectives of the study were to report the development of a core curriculum that details the clinical conditions medical students should be able to manage…”
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Identifying incident cancer cases in dispensing claims: A validation study using Australia's Repatriation Pharmaceutical Benefits Scheme (PBS) data by Daniels, B, Tervonen, H E, Pearson, S-A

“…Dispensing claims are used commonly as proxy measures in pharmacoepidemiological studies; however, their validity is often untested. To assess the performance…”
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