Search Results - "Pearson, R.B."

771: Targeting MYC-driven growth and proliferation in prostate cancer by Rebello, R, Drygin, D, Cameron, D, Risbridger, G.P, Pearson, R.B, Hannan, R.D, Furic, L

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70: Proffered Paper: Inhibition of RNA Polymerase I transcription by CX-5461 as a completely new approach to treat highly refractory haematological malignancies by Hannan, R, Hein, N, O’Brien, S.E, Drygin, D, Cullinane, C, Matthews, G, Johnstone, R.W, Pearson, R.B, McArthur, G, Harrison, S

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The Akt kinase signals directly to endothelial nitric oxide synthase by Michell, B.J., Griffiths, J.E., Mitchelhill, K.I., Rodriguez-Crespo, I., Tiganis, T., Bozinovski, S., de Montellano, P.R.Ortiz, Kemp, B.E., Pearson, R.B.

“…Endothelial nitric oxide synthase (eNOS) is an important modulator of angiogenesis and vascular tone [1]. It is stimulated by treatment of endothelial cells in…”
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594 A novel form of cellular senescence induced by hyper-activation of the PI3K/Akt pathway by Astle, M.V, Hannan, R.D, Pearson, R.B

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The characterisation of PKB isoform specific signalling by Lee, R.S, Hannan, K.M, Hannan, R.D, Pearson, R.B

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Investigating the role of serum and glucocorticoid inducible kinase 3 in promoting cell transformation by Bruhn, M.A, Riddell, K, Abbott, C.A, Pearson, R.B, Sheppard, K.E, Hannan, R.D

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AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy by Astle, M V, Hannan, K M, Ng, P Y, Lee, R S, George, A J, Hsu, A K, Haupt, Y, Hannan, R D, Pearson, R B

“…The phosphatidylinositol 3-kinase (PI3K)/AKT and RAS oncogenic signalling modules are frequently mutated in sporadic human cancer. Although each of these…”
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The calmodulin binding domain of chicken smooth muscle myosin light chain kinase contains a pseudosubstrate sequence by Kemp, B.E., Pearson, R.B., Guerriero, V, Bagchi, I.C., Means, A.R.

“…Smooth muscle myosin light chain kinase contains a 64 residue sequence that binds calmodulin in a Ca2+-dependent manner (Guerriero, V., Jr., Russo, M. A., and…”
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Antimicrobial use practices, attitudes and responsibilities in UK farm animal veterinary surgeons by Coyne, L.A., Latham, S.M., Dawson, S., Donald, I.J., Pearson, R.B., Smith, R.F., Williams, N.J., Pinchbeck, G.L.

“…Increasing levels of antimicrobial resistance in human and veterinary medicine have raised concerns around the issue of overprescribing and the indiscriminate…”
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Dysregulation of RNA polymerase I transcription during disease by Hannan, K.M., Sanij, E., Rothblum, L.I., Hannan, R.D., Pearson, R.B.

“…Transcription of the ribosomal RNA genes by the dedicated RNA polymerase I enzyme and subsequent processing of the ribosomal RNA are fundamental control steps…”
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Intraoperative Hemorrhage During Patent Ductus Arteriosus Ligation in Dogs by Hunt, Geraldine B., Simpson, David J., Beck, Jason A., Goldsmid, Sarah E., Lawrence, Darien, Pearson, Martin R.B., Bellenger, Christopher R.

“…Objective— To determine the prevalence of intraoperative hemorrhage in a consecutive series of dogs undergoing patent ductus arteriosus (PDA) ligation at a…”
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PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity by Gilan, O, Diesch, J, Amalia, M, Jastrzebski, K, Chueh, A C, Verrills, N M, Pearson, R B, Mariadason, J M, Tulchinsky, E, Hannan, R D, Dhillon, A S

“…The proto-oncogene c-Jun is a component of activator protein-1 (AP-1) transcription factor complexes that regulates processes essential for embryonic…”
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PR55[alpha]-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity by Gilan, O, Diesch, J, Amalia, M, Jastrzebski, K, Chueh, A.C, Verrills, N.M, Pearson, R.B, Mariadason, J.M, Tulchinsky, E, Hannan, R.D, Dhillon, A.S

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Phosphorylation site sequence of smooth muscle myosin light chain ( Mr = 20 000) by Pearson, R.B., Jakes, R., John, M., Kendrick-Jones, J., Kemp, B.E.

“…The amino terminal sequence of the myosin light chain ( M r = 20 000) isolated from chicken gizzards was found to be…”
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Protein kinase-dependent phosphorylation of the Menkes copper P-type ATPase by Voskoboinik, I, Fernando, R, Veldhuis, N, Hannan, K.M, Marmy-Conus, N, Pearson, R.B, Camakaris, J

“…The Menkes copper-translocating P-type ATPase (ATP7A; MNK) is a key regulator of copper homeostasis in humans. It has a dual role in supplying copper to…”
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633 Specific activation of Akt3 in ovarian cancer by Cristiano, B.E., Cornus, N.Marmy, Hannan, K.M., Campbell, I., Pearson, R.B.

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Tachycardia-induced cardiomyopathy in a young Boxer dog with supraventricular tachycardia due to an accessory pathway. [Erratum: 2006 Dec., v. 84, no. 12, p. 417.] by Foster, S.F, Hunt, G.B, Thomas, S.P, Ross, D.L, Pearson, M.R.B, Malik, R

“…A 1‐year‐old male Boxer dog presented with sustained supraventricular tachycardia and tachycardia‐induced cardiomyopathy. Conversion to sinus rhythm was…”
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Quantum-Chromodynamic β Function at Intermediate and Strong Coupling by Kogut, John B., Pearson, Robert B., Shigemitsu, Junko

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The immunosuppressant rapamycin induces inactivation of p70s6k through dephosphorylation of a novel set of sites by FERRARI, S, PEARSON, R. B, SIEGMANN, M, KOZMA, S. C, THOMAS, G

“…The immunosuppressant rapamycin selectively abolishes phosphorylation and activation of p70s6k/p85s6k at concentrations that either block or suppress cell…”
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Hadron masses in quantum chromodynamics on the transverse lattice by Bardeen, William A., Pearson, Robert B., Rabinovici, Eliezer

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