Search Results - "Pearson, Erika L"
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Ipa1 Is an RNA Polymerase II Elongation Factor that Facilitates Termination by Maintaining Levels of the Poly(A) Site Endonuclease Ysh1
Published in Cell reports (Cambridge) (12-02-2019)“…The yeast protein Ipa1 was recently discovered to interact with the Ysh1 endonuclease of the pre-mRNA cleavage and polyadenylation (C/P) machinery, and Ipa1…”
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Journal Article -
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Ipa1 Is an RNA Polymerase II Elongation Factor that Facilitates Termination by Maintaining Levels of the Poly(A) Site Endonuclease Ysh1
Published in Cell reports (Cambridge) (04-08-2020)Get full text
Journal Article -
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A Defective mRNA Cleavage and Polyadenylation Complex Facilitates Expansions of Transcribed (GAA)n Repeats Associated with Friedreich’s Ataxia
Published in Cell reports (Cambridge) (05-09-2017)“…Expansions of microsatellite repeats are responsible for numerous hereditary diseases in humans, including myotonic dystrophy and Friedreich’s ataxia. Whereas…”
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Journal Article -
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Unravelling the means to an end: RNA polymerase II transcription termination
Published in Nature reviews. Molecular cell biology (01-05-2011)“…Key Points RNA polymerase II (Pol II) transcribes all eukaryotic protein-coding genes and most non-coding RNA genes. The final step of transcription is…”
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Journal Article -
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Dismantling Promoter-driven RNA Polymerase II Transcription Complexes in Vitro by the Termination Factor Rat1
Published in The Journal of biological chemistry (05-07-2013)“…Proper RNA polymerase II (Pol II) transcription termination is essential to generate stable transcripts, to prevent interference at downstream loci, and to…”
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Journal Article -
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Regulation of transcription elongation via interactions of RNA polymerase with sequence elements and accessory factors
Published 2008“…RNA polymerase (RNAP) is the enzyme responsible for catalyzing the first step in a cascade of events leading towards gene expression. Since the dissemination…”
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Dissertation -
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Regulation of transcription elongation via interactions of RNA polymerase with sequence elements and accessory factors
Published in Dissertation Abstracts International. Vol. 69, no. 11, suppl. B, 157 p. 2008 (01-01-2008)“…RNA polymerase (RNAP) is the enzyme responsible for catalyzing the first step in a cascade of events leading towards gene expression. Since the dissemination…”
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Book Chapter