Search Results - "Pearn, Armin"
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Relationships between metabolic profiles and gene expression in liver and leukocytes of dairy cows in early lactation
Published in Journal of dairy science (01-03-2021)“…Homeorhetic mechanisms assist dairy cows in the transition from pregnancy to lactation. Less successful cows develop severe negative energy balance (NEB),…”
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An organism-wide ATAC-seq peak catalog for the bovine and its use to identify regulatory variants
Published in Genome research (01-10-2023)“…We report the generation of an organism-wide catalog of 976,813 -acting regulatory elements for the bovine detected by the assay for transposase accessible…”
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Influence of the concentrate inclusion level in a grass silage–based diet on hepatic transcriptomic profiles in Holstein-Friesian dairy cows in early lactation
Published in Journal of dairy science (01-08-2023)“…Excessive negative energy balance in early lactation is linked to an increased disease risk but may be mitigated by appropriate nutrition. The liver plays…”
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Prediction of key milk biomarkers in dairy cows through milk mid-infrared spectra and international collaborations
Published in Journal of dairy science (01-03-2024)“…At the individual cow level, suboptimum fertility, mastitis, negative energy balance, and ketosis are major issues in dairy farming. These problems are…”
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Genome-wide association study and functional annotation analyses for nitrogen efficiency index and its composition traits in dairy cattle
Published in Journal of dairy science (01-05-2023)“…The aims of this study were (1) to identify genomic regions associated with a N efficiency index (NEI) and its composition traits and (2) to analyze the…”
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Estimation of genetic parameters for predicted nitrogen use efficiency and losses in early lactation of Holstein cows
Published in Journal of dairy science (01-04-2021)“…The objective of this study was to estimate genetic parameters of predicted N use efficiency (PNUE) and N losses (PNL) as proxies of N use and loss for…”
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Potential of milk mid-IR spectra to predict metabolic status of cows through blood components and an innovative clustering approach
Published in Animal (Cambridge, England) (01-03-2019)“…Unbalanced metabolic status in the weeks after calving predisposes dairy cows to metabolic and infectious diseases. Blood glucose, IGF-I, non-esterified fatty…”
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Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes
Published in BMC genomics (25-09-2021)“…Previous studies have identified many immune pathways which are consistently altered in humans and model organisms as they age. Dairy cows are often culled at…”
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Hepatic Global Transcriptomic Profiles of Holstein Cows According to Parity Reveal Age-Related Changes in Early Lactation
Published in International journal of molecular sciences (01-06-2023)“…Cows can live for over 20 years, but their productive lifespan averages only around 3 years after first calving. Liver dysfunction can reduce lifespan by…”
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Proportion of Concentrate in the Diet of Early Lactation Dairy Cows Has Contrasting Effects on Circulating Leukocyte Global Transcriptomic Profiles, Health and Fertility According to Parity
Published in International journal of molecular sciences (20-12-2022)“…The functionality of circulating leukocytes in dairy cows is suppressed after calving, with negative energy balance as a risk factor. Leukocyte transcriptomic…”
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Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis
Published in Molecular biology reports (01-05-2021)“…Bovine mastitis, an inflammatory disease of the mammary gland, is classified as subclinical or clinical. Circulating neutrophils are recruited to the udder to…”
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Only few benefits from propylene glycol drench in early lactation for cows identified as physiologically imbalanced based on milk spectra analyses
Published in Journal of dairy science (01-02-2020)“…The main objective of this study was to test the efficiency of a management system combining metabolic clustering of cows based on Fourier-transform…”
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Predicting physiological imbalance in Holstein dairy cows by three different sets of milk biomarkers
Published in Preventive veterinary medicine (01-06-2020)“…•Identifying physiological imbalance/disease risk in dairy cows for herd management.•Blood biomarkers are relevant indicators but not generally applicable…”
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Validating genomic prediction for nitrogen efficiency index and its composition traits of Holstein cows in early lactation
Published in Journal of animal breeding and genetics (1986) (01-11-2023)“…Nitrogen (N) use efficiency (NUE) is an economically important trait for dairy cows. Recently, we proposed a new N efficiency index (NEI), that simultaneously…”
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Expert-based development of a generic HACCP-based risk management system to prevent critical negative energy balance in dairy herds
Published in Preventive veterinary medicine (01-02-2020)“…The objective of this study was to develop a generic risk management system based on the Hazard Analysis and Critical Control Point (HACCP) principles for the…”
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Transcriptomic Analysis of Circulating Leukocytes Obtained during the Recovery from Clinical Mastitis Caused by Escherichia coli in Holstein Dairy Cows
Published in Animals (Basel) (21-08-2022)“…The risk and severity of clinical infection with Escherichia coli as a causative pathogen for bovine mastitis is influenced by the hosts’ phenotypic and…”
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Economic value of information from an alert system on physiological imbalance in fresh cows
Published in Preventive veterinary medicine (01-08-2020)“…Physiological imbalance is an abnormal physiological condition that cannot be directly observed but is assumed to precede subclinical and clinical diseases in…”
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Mining the Unmapped Reads in Bovine RNA-Seq Data Reveals the Prevalence of Bovine Herpes Virus-6 in European Dairy Cows and the Associated Changes in Their Phenotype and Leucocyte Transcriptome
Published in Viruses (16-12-2020)“…Microbial RNA is detectable in host samples by aligning unmapped reads from RNA sequencing against taxon reference sequences, generating a score proportional…”
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Validation of Dairy Cow Bodyweight Prediction Using Traits Easily Recorded by Dairy Herd Improvement Organizations and Its Potential Improvement Using Feature Selection Algorithms
Published in Animals (Basel) (30-04-2021)“…Knowing the body weight (BW) of a cow at a specific moment or measuring its changes through time is of interest for management purposes. The current work aimed…”
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